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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl198228170-73</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-10472</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Влияние глюкокортикоидов и катехоламинов на состояние лизосомального аппарата тканей кроликов с экспериментальным диабетом</article-title><trans-title-group xml:lang="en"><trans-title>Effect of glucocorticoids and catecholamines on the state of the tissue lysosomal apparatus in rabbits with experimental diabetes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панин</surname><given-names>Л Е</given-names></name><name name-style="western" xml:lang="en"><surname>Panin</surname><given-names>L E</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Климентьева</surname><given-names>Т К</given-names></name><name name-style="western" xml:lang="en"><surname>Klimenteva</surname><given-names>T K</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маянская</surname><given-names>Н Н</given-names></name><name name-style="western" xml:lang="en"><surname>Mayanskaya</surname><given-names>N N</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт экспериментальной и клинической медицины</institution></aff><aff xml:lang="en"><institution>Research Center for Clinical and Experimental Medicine or Scientific Centre of Clinical and Experimental Medicine under the Siberian Branch of the Russian Academy of Medical Sciences</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>1982</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>1982</year></pub-date><volume>28</volume><issue>1</issue><issue-title>ТОМ 28, №1 (1982)</issue-title><fpage>70</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Панин Л.Е., Климентьева Т.К., Маянская Н.Н., 1982</copyright-statement><copyright-year>1982</copyright-year><copyright-holder xml:lang="ru">Панин Л.Е., Климентьева Т.К., Маянская Н.Н.</copyright-holder><copyright-holder xml:lang="en">Panin L.E., Klimenteva T.K., Mayanskaya N.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/10472">https://www.probl-endojournals.ru/jour/article/view/10472</self-uri><abstract><p>Administration to rabbits of hydrocortisone (8 mg/kg) and adrenaline (0.3 ml of 0.1% solution) during mild dithizone diabetes simulated hormonal reconstructions of the body exposed to stress. Activation of the cellular lysosomal apparatus occurs in such hormonal situation. In the liver this in manifested by an increase in the acid phosphatase, cathepside D, and beta-glucosidase free activity and by reduction in the resistance of lysosomal membranes to the effect of osmotic shock. Increase in the total acid hydrolase activity was detected in the cardiac and skeletal muscles.</p></abstract><kwd-group xml:lang="en"><kwd>liver</kwd><kwd>adrenaline</kwd><kwd>hydrocortisone</kwd><kwd>lysosomal membranes</kwd><kwd>lysosomal apparatus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bessey О. A., Lowry О. Н., Brock М.J.//J. biol. Chem., 1946, v. 164, p. 321-323.</mixed-citation><mixed-citation xml:lang="en">Bessey О. A., Lowry О. Н., Brock М.J.//J. biol. 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