problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl198531472-75problendo-10501Research ArticleСтатьиArticlesПоглощение липопротеидов плазмы крови стероидпродуцирующими органами у крысPlasma lipoprotein absorption by steroid-producing organs in the ratПоляковЛ МPolyakovL M-ПанинЛ ЕPaninL E-Научно-исследовательский институт экспериментальной и клинической медицины;Научно-исследовательский институт биохимии СО РАМНResearch Center for Clinical and Experimental Medicine or Scientific Centre of Clinical and Experimental Medicine under the Siberian Branch of the Russian Academy of Medical Sciences;Scientific Research Institute of Biochemistry of Siberian Branch of Russian Academy of Medical Sciences198515121985314ТОМ 31, №4 (1985)7275Copyright © Поляков Л.М., Панин Л.Е., 19851985Поляков Л.М., Панин Л.Е.Polyakov L.M., Panin L.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/10501

A study was made of the blood plasma iodinated lipoprotein (LP) absorption by the organs and tissues of rats following i.v. injection. The adrenals and ovaries were shown to effectively absorb high density lipoproteins (HDL) as compared to the liver, spleen, kidneys, heart and lungs. HDL absorption reached its maximum 30 min after LP injection. Six hours later the adrenal tissue radioactivity level decreased by 30% and after 12 h 3-fold. The time-course of HDL absorption by the ovaries was characterized by a slow increase in radioactivity after 6 h and a gradual decrease of the label index after 12 h. Differences in HDL absorption by the adrenals and ovaries reflected some functional features of these steroid producing organs.

lipoproteincorticosteronelow density lipoproteinhigh density lipoproteinvery low density lipoproteinReferences

The authors declare that there are no conflicts of interest present.