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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl200551650-53</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-10830</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Полинеоплазия: рак щитовидной железы и ракмолочной железы - частота, причины, механизмы развития</article-title><trans-title-group xml:lang="en"><trans-title>Polineoplasia: thyroid cancer and breast cancer: incidence, causes, mechanisms of development</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зотов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zotov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра онкологии</p></bio><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;Национальный медицинский университет&lt;/p&gt;</institution><country>Украина</country></aff><aff xml:lang="en"><institution>&lt;p&gt;National Medical University&lt;/p&gt;</institution><country>Ukraine</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2005</year></pub-date><volume>51</volume><issue>6</issue><issue-title>ТОМ 51, №6 (2005)</issue-title><fpage>50</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зотов А.С., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Зотов А.С.</copyright-holder><copyright-holder xml:lang="en">Zotov A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/10830">https://www.probl-endojournals.ru/jour/article/view/10830</self-uri><abstract><p>Драматическая ситуация с заболеваемостью и смертностью от рака молочной железы (РМЖ), сложившаяся в последние десятилетия минувшего века в индустриально развитых странах мира, придала этому заболеванию статус не только медицинской, но и социальной проблемы. Общество реагировало на это адекватно: ряд предпринятых мер по противораковой пропаганде, ранней диагностике, разработке и широкому применению эффективных методов лечения позволил переломить неблагоприятную тенденцию в смертности при одновременном признании ограниченности возможностей современной медицины в предотвращении РМЖ. Мировые тенденции к повышению продолжительности жизни после излечения РМЖ привели к росту числа пациенток, заболевших впоследствии второй злокачественной опухолью. Пристальное внимание исследователей привлекает сочетание РМЖ и рака щитовидной железы (РЩЖ).</p></abstract><trans-abstract xml:lang="en"><p>The dramatic situation with the incidence and mortality from breast cancer that has developed in the last decades of the past century in the industrialized countries of the world has given this disease the status of not only a medical, but also a social problem. The society reacted to this adequately: a number of measures taken for anti-cancer propaganda, early diagnosis, development and widespread use of effective methods of treatment allowed us to reverse the unfavorable trend in mortality while recognizing the limited possibilities of modern medicine in preventing breast cancer. World trends in increasing life expectancy after curing breast cancer have led to an increase in the number of patients subsequently ill with a second malignant tumor. The attention of researchers is attracted by the combination of breast cancer and thyroid cancer.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак щитовидной железы</kwd><kwd>рак молочной железы</kwd><kwd>полинейоплазия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thyroid cancer</kwd><kwd>breast cancer</kwd><kwd>polineoplasia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Агеев И.С., Великолуг А.Н., Жданова Т.Р., Жукова В.М. // Рос. онкол. журн. - 1997. - № 3. - С. 41-42.</mixed-citation><mixed-citation xml:lang="en">Агеев И.С., Великолуг А.Н., Жданова Т.Р., Жукова В.М. // Рос. онкол. журн. - 1997. - № 3. - С. 41-42.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бехтерева С.А. // Вестн. хир. - 1996. - № 4. - С. 18-21.</mixed-citation><mixed-citation xml:lang="en">Бехтерева С.А. // Вестн. хир. - 1996. - № 4. - С. 18-21.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Демина Н.А. // Вопр. онкол. - 1979. - № 5. - С. 47-50. 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