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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl20065246-8</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-10869</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая эндокринология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical endocrinology</subject></subj-group></article-categories><title-group><article-title>Распространенность ретинопатии среди больных сахарным диабетом 2-го типа</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of retinopathy in patients with type 2 diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Метревели</surname><given-names>Д С</given-names></name><name name-style="western" xml:lang="en"><surname>Metrevell</surname><given-names>D S</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сулханишвили</surname><given-names>М З</given-names></name><name name-style="western" xml:lang="en"><surname>Sulkhanlshvili</surname><given-names>M Z</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маргвелашвили</surname><given-names>М З</given-names></name><name name-style="western" xml:lang="en"><surname>Margvelashvilt</surname><given-names>M Z</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Кафедра эндокринологии (зав. - проф. Д. С. Метревели) Государственной медицинской академии Грузии, Тбилиси</institution></aff><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2006</year></pub-date><volume>52</volume><issue>4</issue><issue-title>ТОМ 52, №4 (2006)</issue-title><fpage>6</fpage><lpage>8</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Метревели Д.С., Сулханишвили М.З., Маргвелашвили М.З., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Метревели Д.С., Сулханишвили М.З., Маргвелашвили М.З.</copyright-holder><copyright-holder xml:lang="en">Metrevell D.S., Sulkhanlshvili M.Z., Margvelashvilt M.Z.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/10869">https://www.probl-endojournals.ru/jour/article/view/10869</self-uri><abstract/><trans-abstract xml:lang="en"><p>The fact that diabetic retinopathy (DP) exists at the preclinical stage of evolution of type 2 diabetes mellitus (DM-2) cannot be' explained in the context of the commonly accepted theory of the etiopathogenesis of diabetic microangiopathy. The purpose of the study was to explore the prevalence of DR among patients with new-onset DM-2 and to analyze the possible causes of development of this complication at an early stage of the disease. The prevalence of DR among patients with new-onset DM-2 was found to be 16.4%. In the new-onset DM-2 patients aged above 45 years, the odds ratio for DR. is 2.6 times greater than that in those aged under 45 years. Based on the results of the study, the authors suggest that there are pathogenetic mechanisms responsible for the initiation of diabetic microvascular pathology to the stabilization of hyperglycemia at the stage of decreased glucose tolerance.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>распространенность</kwd><kwd>сахарный диабет 2-го типа</kwd><kwd>диабетическая ретинопатия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>prevalence</kwd><kwd>diabetic retinopathy</kwd><kwd>type 2 diabetes mellltus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И. И., Шестакова М. В., Миленькая Т. М. Сахарный диабет: ретинопатия, нефропатия. - М., 2001.</mixed-citation><mixed-citation xml:lang="en">Дедов И. И., Шестакова М. В., Миленькая Т. М. 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