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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl200753234-40</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-10929</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Иммуновоспалительные механизмы в формировании диабетической нефропатии</article-title><trans-title-group xml:lang="en"><trans-title>Immune inflammatory mechanisms in the development of diabetic nephropathy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бондарь</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bondar</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Климонтов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Klimontov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;Новосибирский государственный медицинский университет&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Novosibirsk State Medical University&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>15</day><month>04</month><year>2007</year></pub-date><volume>53</volume><issue>2</issue><issue-title>ТОМ 53, №2 (2007)</issue-title><fpage>34</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бондарь И.А., Климонтов В.В., 2007</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="ru">Бондарь И.А., Климонтов В.В.</copyright-holder><copyright-holder xml:lang="en">Bondar I.A., Klimontov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/10929">https://www.probl-endojournals.ru/jour/article/view/10929</self-uri><abstract><p>Диабетическую нефропатию долгое время относили к неиммунным и невоспалительным поражениям почек, считая основной причиной ее развития метаболические и гемодинамические факторы. Однако в последние годы установлено влияние воспаления на развитие диабетического нефросклероза. Это послужило основанием к дальнейшему развитию концепции патогенеза диабетической нефропатии, разработке методов ее диагностики и лечения.</p></abstract><trans-abstract xml:lang="en"><p>Diabetic nephropathy has long been attributed to non-immune and non-inflammatory lesions of the kidneys, considering metabolic and hemodynamic factors to be the main reason for its development. However, in recent years, the effect of inflammation on the development of diabetic nephrosclerosis has been established. This served as the basis for the further development of the concept of the pathogenesis of diabetic nephropathy, the development of methods for its diagnosis and treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нефропатия</kwd><kwd>сахарный диабет</kwd><kwd>воспаление</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nephropathy</kwd><kwd>diabetes</kwd><kwd>inflammation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">дарь И. А. Клинические, метаболические и иммунные особенности развития и прогрессирования поздних осложнений сахарного диабета: Автореф. дис. ... Д-ра мед. наук. - Новосибирск, 1997.</mixed-citation><mixed-citation xml:lang="en">дарь И. А. Клинические, метаболические и иммунные особенности развития и прогрессирования поздних осложнений сахарного диабета: Автореф. дис. ... 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