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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl200753518-21</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-10966</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая эндокринология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical endocrinology</subject></subj-group></article-categories><title-group><article-title>Ассоциации зобной эндемии и латентного дефицита железа в Западно-Сибирском регионе</article-title><trans-title-group xml:lang="en"><trans-title>Association of goiter endemic and latent iron deficiency in Western Siberia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Туровинина</surname><given-names>Е. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Turovinina</surname><given-names>E. F.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суплотова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Suplotova</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Южакова</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuzhakova</surname><given-names>N. Yu.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суплотов</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Suplotov</surname><given-names>S. N.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шарухо</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharukho</surname><given-names>G. V.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ГОУ ВПО Тюменская государственная медицинская академия&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Tyumen State Medical Academy&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>&lt;p&gt;Территориальное управление Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека по Тюменской области&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Territorial Administration of the Federal Service for Supervision of Consumer Rights Protection and Human Well-Being in the Tyumen Region&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>15</day><month>10</month><year>2007</year></pub-date><volume>53</volume><issue>5</issue><issue-title>ТОМ 53, №5 (2007)</issue-title><fpage>18</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Туровинина Е.Ф., Суплотова Л.А., Южакова И.Ю., Суплотов С.Н., Шарухо Г.В., 2007</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="ru">Туровинина Е.Ф., Суплотова Л.А., Южакова И.Ю., Суплотов С.Н., Шарухо Г.В.</copyright-holder><copyright-holder xml:lang="en">Turovinina E.F., Suplotova L.A., Yuzhakova N.Y., Suplotov S.N., Sharukho G.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/10966">https://www.probl-endojournals.ru/jour/article/view/10966</self-uri><abstract><p>Цель исследования - изучение распространенности и ассоциации латентного дефицита железа и зобной эндемии у детей препубертатного возраста в Западно-Сибирском регионе. В период с 2005 по 2006 г. обследовано 2238 школьников препубертатного возраста (8-12 лет), проживающих в 3 субъектах Тюменской области. Исследованы традиционные критерии йододефицитных состояний (ЙДС): йодурия, частота зоба пальпаторно и УЗИ. Сывороточный ферритин определен методом иммуноферментного анализа ELISA наборами DRG-Dlagnostlcs (США). Установлено, что в Западно-Сибирском регионе на фоне программы профилактики ЙДС отмечается нормализация медианы йодурии, составившей 117 мкг/л. Тяжесть зобной эндемии в 2006 г. с учетом нормативов ВОЗ (2003 г.) расценивается как умеренная в южных районах области и тяжелая в автономных округах. По критерию сывороточного ферритина ниже 15 мкг/л у школьников повсеместно выявлена высокая частота латентного дефицита железа. Отсюда следует вывод, что ассоциация между сывороточным ферритином и объемами щитовидной железы обусловлена сочетанием двух значимых для популяции состояний: тяжелой зобной эндемии и частого латентного дефицита.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of the investigation was to study the prevalence of latent iron deficiency and goiter endemic and their association in prepubertal children in Western Siberia. A total of 2238 prepubertal children (8-12 years) living in 3 subjects of the Tyumen Region were examined in 2005-2006. The classical criteria for Iodine deficiency (ID), such as iodurla, the frequency of goiter at palpation and ultrasonography, were studied. Serum ferritln was determined by enzyme-linked immunosorbent assay using the DRG-Diagnostics ПРОБЛЕМЫ ЭНДОКРИНОЛОГИИ. 2007. Т. 53, № 5. kits (USA). There was normalization of the median ioduria, which was 117,', in the implementation of the ID prevention program in Western Siberia. By taking into account the 2003 WHO standards, the severity of goiter endemic in 2006 is regarded as moderate in the southern districts of the region and as severe in its autonomous areas. In terms of a serum ferritin level of less than 15 a high frequency of latent iron deficiency was found in the everywhere. Hence it follows that the association of the serum ferritin levels with the thyroid volumes is caused by a concomitance of two significant conditions: severe goiter endemic and frequent latent iron deficiency.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>зобная эндемия</kwd><kwd>латентный дефицит железа</kwd></kwd-group><kwd-group xml:lang="en"><kwd>goiter endemic</kwd><kwd>latent iron deficiency</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Суплотова Л. А. 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