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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl200854146-50</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-10998</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Дискуссия</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Discussion</subject></subj-group></article-categories><title-group><article-title>Верхний референсный уровень ТТГ - достаточно ли аргументов для его изменения</article-title><trans-title-group xml:lang="en"><trans-title>The upper reference level of TSH: are there sufficient arguments for its change</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фадеев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fadeyev</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ФГУ Эндокринологический научный центр Росмсдтехнологий&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinolgy Research Centre of Rosmedtechnology&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>15</day><month>02</month><year>2008</year></pub-date><volume>54</volume><issue>1</issue><issue-title>ТОМ 54, №1 (2008)</issue-title><fpage>46</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фадеев В.В., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Фадеев В.В.</copyright-holder><copyright-holder xml:lang="en">Fadeyev V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/10998">https://www.probl-endojournals.ru/jour/article/view/10998</self-uri><abstract><p>Статья посвящена рассмотрению вопроса о верхнем референсном уровне ТТГ и аргументов для его изменения, являясь откликом на статью Л. Н. Самсоновой и Э. П. Касаткиной "Нормативы уровня ТТГ: современное состояние проблемы".</p></abstract><trans-abstract xml:lang="en"><p>The article is devoted to the discussion of the issue associated with the upper reference level of TSH and the arguments for its change, being the response to the article edited by L. N. Samsonova and E. P. Kasatkina "TSH level standards: current state of the problem".</p></trans-abstract><kwd-group xml:lang="ru"><kwd>верхний референсный уровень</kwd><kwd>ТТГ</kwd><kwd>аргументы</kwd><kwd>изменения</kwd><kwd>отклик</kwd></kwd-group><kwd-group xml:lang="en"><kwd>upper reference level</kwd><kwd>TSH</kwd><kwd>arguments</kwd><kwd>change</kwd><kwd>response</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Фадеев В. В. // Клин. тиреоидол. - 2004. - N 3. - С. 5- 9.</mixed-citation><mixed-citation xml:lang="en">Фадеев В. 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