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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl20085433-7</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11010</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая эндокринология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical endocrinology</subject></subj-group></article-categories><title-group><article-title>Диабетон MB в лечении сахарного диабета 2-го типа</article-title><trans-title-group xml:lang="en"><trans-title>Diabeton MR in the treatment of type 2 diabetes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишкова</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishkova</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ФГУ Государственный научно-исследовательский центр профилактической медицины Росздрава&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p style="text-align: left;"&gt;State Research Center for Preventive Medicine of Roszdrav&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2008</year></pub-date><volume>54</volume><issue>3</issue><issue-title>ТОМ 54, №3 (2008)</issue-title><fpage>3</fpage><lpage>7</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шишкова В.Н., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Шишкова В.Н.</copyright-holder><copyright-holder xml:lang="en">Shishkova V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11010">https://www.probl-endojournals.ru/jour/article/view/11010</self-uri><abstract><p>Сахарный диабет 2-го типа (СД2) признан неинфекционной эпидемией современности. Поданным ВОЗ, в 2007 г. в мире насчитывалось около 246 млн больных СД, эксперты прогнозируют, что к 2025 г. их будет около 380 млн, из которых более 90% составят больные СД2. Возраст больных на момент дебюта СД2 постепенно уменьшается, отмечается тревожное повышение риска развития этого заболевания у молодых людей, подростков и детей. Изучение патофизиологических основ развития СД2 дало возможность представления будущих масштабов его распространенности и их причин.</p></abstract><trans-abstract xml:lang="en"><p>Type 2 diabetes mellitus (T2DM) is recognized as a non-infectious epidemic of our time. According to the WHO, in 2007 there were about 246 million patients with diabetes in the world, experts predict that by 2025 there will be about 380 million, of which more than 90% will be patients with type 2 diabetes [<xref ref-type="bibr" rid="cit23">23</xref>]. The age of patients at the time of the onset of T2DM is gradually decreasing, there is an alarming increase in the risk of developing this disease in young people, adolescents and children [<xref ref-type="bibr" rid="cit1">1</xref>]. The study of the pathophysiological basis for the development of T2DM made it possible to present the future extent of its prevalence and their causes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>нарушение толерантности к глюкозе</kwd><kwd>инфаркт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes</kwd><kwd>impaired glucose tolerance</kwd><kwd>heart attack</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И. И., Ремизов О. В., Петеркова В. А. // Сахарный диабет. - 2001. - № 4. - С. 26-31.</mixed-citation><mixed-citation xml:lang="en">Дедов И. И., Ремизов О. В., Петеркова В. 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