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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl200854632-37</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11053</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Применение римонабанта при сахарном диабете 2-го типа</article-title><trans-title-group xml:lang="en"><trans-title>Use of rimonabant in type 2 diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шварц</surname><given-names>В</given-names></name><name name-style="western" xml:lang="en"><surname>Shvarts</surname><given-names>V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2008</year></pub-date><volume>54</volume><issue>6</issue><issue-title>ТОМ 54, №6 (2008)</issue-title><fpage>32</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шварц В., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Шварц В.</copyright-holder><copyright-holder xml:lang="en">Shvarts V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11053">https://www.probl-endojournals.ru/jour/article/view/11053</self-uri><abstract/><trans-abstract xml:lang="en"/></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO. Diabetes Action Now - An Initiative of the WHO and the International Diabetes Federation. - Geneva, 2004. - P. 8.</mixed-citation><mixed-citation xml:lang="en">WHO. Diabetes Action Now - An Initiative of the WHO and the International Diabetes Federation. - Geneva, 2004. - P. 8.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Liebl A., Spannheimer A., Reitberger U. et al. Diabetes und StoffwechseI. - 2002. - Bd 11, N 2. - S. 55-61.</mixed-citation><mixed-citation xml:lang="en">Liebl A., Spannheimer A., Reitberger U. et al. Diabetes und StoffwechseI. - 2002. - Bd 11, N 2. - S. 55-61.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Jacob S., Balletshofer В., Haring H. U. Diabetologie Kompakt. -Stuttgart, 2004. - S. 240-249.</mixed-citation><mixed-citation xml:lang="en">Jacob S., Balletshofer В., Haring H. U. Diabetologie Kompakt. -Stuttgart, 2004. - S. 240-249.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Haffner S. M, Lehto S., Ronnemaa T. et al. // N. Engl. J. Med. - 1998. - Vol. 339. - P. 229-234.</mixed-citation><mixed-citation xml:lang="en">Haffner S. M, Lehto S., Ronnemaa T. et al. // N. Engl. J. Med. - 1998. - Vol. 339. - P. 229-234.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Grundy S. M., Cleeman J. L, Daniels S. R. et al. // Circula-tion. - 2005. - Vol. 112. - P. 2735-2752.</mixed-citation><mixed-citation xml:lang="en">Grundy S. M., Cleeman J. L, Daniels S. R. et al. // Circula-tion. - 2005. - Vol. 112. - P. 2735-2752.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lakka H. M., Laaksonen D. E, Laaka T. A. et al. // J. A. M. A. - 2002. - Vol. 288. - P. 2709-2716.</mixed-citation><mixed-citation xml:lang="en">Lakka H. M., Laaksonen D. E, Laaka T. A. et al. // J. A. M. A. - 2002. - Vol. 288. - P. 2709-2716.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Holman R. А, Thorne К. I., Farmer A. J. et al. // J. Engl. J. Med. - 2007. - Vol. 357. - P. 1716-1730.</mixed-citation><mixed-citation xml:lang="en">Holman R. А, Thorne К. I., Farmer A. J. et al. // J. Engl. J. Med. - 2007. - Vol. 357. - P. 1716-1730.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Lee M, Aronne L. J. // Am. J. Cardiol. - 2007. - Vol. 99. -P. 68B-79B.</mixed-citation><mixed-citation xml:lang="en">Lee M, Aronne L. J. // Am. J. Cardiol. - 2007. - Vol. 99. -P. 68B-79B.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Di Marzo V., Bifulco M., De Petrocellis L. // Nat. Rev. Drug Discav. - 2004. - Vol. 3. - P, 771-784.</mixed-citation><mixed-citation xml:lang="en">Di Marzo V., Bifulco M., De Petrocellis L. // Nat. Rev. Drug Discav. - 2004. - Vol. 3. - P, 771-784.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kirkham T. C, Williams C. M, Fezza F. et al. // Br. J. Phar-macol. - 2002. - Vol. 136. - P. 550-557.</mixed-citation><mixed-citation xml:lang="en">Kirkham T. C, Williams C. M, Fezza F. et al. // Br. J. Phar-macol. - 2002. - Vol. 136. - P. 550-557.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Wang J., Ueda N. // Curr. Opin. Nephrol. Hypertens. - 2008. -Vol. 17. - P. 1-10.</mixed-citation><mixed-citation xml:lang="en">Wang J., Ueda N. // Curr. Opin. Nephrol. Hypertens. - 2008. -Vol. 17. - P. 1-10.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Mechoulam R. Cannabis as a Therapeutic Agent. - Boca Ra-ton, I986.</mixed-citation><mixed-citation xml:lang="en">Mechoulam R. Cannabis as a Therapeutic Agent. - Boca Ra-ton, I986.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Plasse T. F., Gorter R. W., Krasnow S. H. et al. // Pharmacol. Biochem. Behav. - 1991. - Vol. 40. - P. 695-700.</mixed-citation><mixed-citation xml:lang="en">Plasse T. F., Gorter R. W., Krasnow S. H. et al. // Pharmacol. Biochem. Behav. - 1991. - Vol. 40. - P. 695-700.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Rowland N. E., Mukherjee M., Robertson K. // Psychopharma-cology (Berl.). - 2001. - Bd 159. - S. 111-116.</mixed-citation><mixed-citation xml:lang="en">Rowland N. E., Mukherjee M., Robertson K. // Psychopharma-cology (Berl.). - 2001. - Bd 159. - S. 111-116.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Hildebrant A. L, Kelly-Sullivan D. M, Bloack S. C. // Eur. J. Pharmacol. - 2003. - Vol. 462. - P. 125-132.</mixed-citation><mixed-citation xml:lang="en">Hildebrant A. L, Kelly-Sullivan D. M, Bloack S. C. // Eur. J. Pharmacol. - 2003. - Vol. 462. - P. 125-132.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Pagotto U. // Lancet. - 2005. - Vol. 365. - P. 1363-1364.</mixed-citation><mixed-citation xml:lang="en">Pagotto U. // Lancet. - 2005. - Vol. 365. - P. 1363-1364.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Schumm-Draeger P., Heinzl S. // AMT. - 2007. - Vol. 25, N 5. - P. 158-165.</mixed-citation><mixed-citation xml:lang="en">Schumm-Draeger P., Heinzl S. // AMT. - 2007. - Vol. 25, N 5. - P. 158-165.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Pi-Sunyer F. X., Aronne L. J., Heshmati H. M. et al. // J. A. M. A. - 2006. - Vol. 295. - P. 761-775.</mixed-citation><mixed-citation xml:lang="en">Pi-Sunyer F. X., Aronne L. J., Heshmati H. M. et al. // J. A. M. A. - 2006. - Vol. 295. - P. 761-775.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Despres J. P., Golay A., Sjostrom L. // N. Engl. J. Med. 2005. -Vol. 353. - P. 2121-2134.</mixed-citation><mixed-citation xml:lang="en">Despres J. P., Golay A., Sjostrom L. // N. Engl. J. Med. 2005. -Vol. 353. - P. 2121-2134.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Van Gaal J. K. // Lancet. - 2005. - Vol. 365. - P. 1389-1397.</mixed-citation><mixed-citation xml:lang="en">Van Gaal J. K. // Lancet. - 2005. - Vol. 365. - P. 1389-1397.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Scheen A. J., Finer N.. Hollander P. et al. // Lancet. - 2006. -Vol. 368. - P. 1660-1672.</mixed-citation><mixed-citation xml:lang="en">Scheen A. J., Finer N.. Hollander P. et al. // Lancet. - 2006. -Vol. 368. - P. 1660-1672.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Hollander P. // Am. J. Med. - 2007. - Vol. 120, N 2. -Suppl. 1. - P. 18-32.</mixed-citation><mixed-citation xml:lang="en">Hollander P. // Am. J. Med. - 2007. - Vol. 120, N 2. -Suppl. 1. - P. 18-32.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Scheen A. J. H. // Best Pract. Res. Clin. Endocrinol. Metab. -2007. - Vol. 21, N 4. - P. 535-553.</mixed-citation><mixed-citation xml:lang="en">Scheen A. J. H. // Best Pract. Res. Clin. Endocrinol. Metab. -2007. - Vol. 21, N 4. - P. 535-553.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Iranmanesh A., Rosenstock J., Hollander P. // Diabet. Med. - 2006.- Vol. 23. - P. 200-410. - Abstr. 637b.</mixed-citation><mixed-citation xml:lang="en">Iranmanesh A., Rosenstock J., Hollander P. // Diabet. Med. - 2006.- Vol. 23. - P. 200-410. - Abstr. 637b.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Pfeiffer A. F„ Bramlage P. // Diabetologe. - 2007. - Bd 3, N 4. - S. 270-277.</mixed-citation><mixed-citation xml:lang="en">Pfeiffer A. F„ Bramlage P. // Diabetologe. - 2007. - Bd 3, N 4. - S. 270-277.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Kunos G. // Am. J. Med. - 2007. - Vol. 120, N 9. - Suppl. 1. - P. S18-S24.</mixed-citation><mixed-citation xml:lang="en">Kunos G. // Am. J. Med. - 2007. - Vol. 120, N 9. - Suppl. 1. - P. S18-S24.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Lange J. H., Coolen H. K. // J. Med. Chem. - 2004. -Vol. 47. - P. 627-643.</mixed-citation><mixed-citation xml:lang="en">Lange J. H., Coolen H. K. // J. Med. Chem. - 2004. -Vol. 47. - P. 627-643.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Christopoulos A., Coles P., Lay M. J. et al. // Br. J. Pharmacol. -2001. - Vol. 132. - P. 1281-1291.</mixed-citation><mixed-citation xml:lang="en">Christopoulos A., Coles P., Lay M. J. et al. // Br. J. Pharmacol. -2001. - Vol. 132. - P. 1281-1291.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Xie X. O., Pavlopoulos S., DiMegtio D. M. et al. // J. Med. Chem. - 1998. - Vol. 41. - P. 167-174.</mixed-citation><mixed-citation xml:lang="en">Xie X. O., Pavlopoulos S., DiMegtio D. M. et al. // J. Med. Chem. - 1998. - Vol. 41. - P. 167-174.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Cota D., Marsicano G., Lutz B. et al. // Int. J. Obes. Relat. Metab. Disord. - 2003. - Vol. 27. - P. 289-301.</mixed-citation><mixed-citation xml:lang="en">Cota D., Marsicano G., Lutz B. et al. // Int. J. Obes. Relat. Metab. Disord. - 2003. - Vol. 27. - P. 289-301.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Harrold J. A., Elliott J. C., King P. J. et al. // Brain Res. - 2002.- Vol. 952. - P. 232-238.</mixed-citation><mixed-citation xml:lang="en">Harrold J. A., Elliott J. C., King P. J. et al. // Brain Res. - 2002.- Vol. 952. - P. 232-238.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Horvath T. L. // J. Clin. Invest. - 2003. - Vol. 112. -P. 323-326.</mixed-citation><mixed-citation xml:lang="en">Horvath T. L. // J. Clin. Invest. - 2003. - Vol. 112. -P. 323-326.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Trayhurn P., Bing C. // Biol. Sci. - 2006. - Vol.361, N 1471. - P. 1237-1249.</mixed-citation><mixed-citation xml:lang="en">Trayhurn P., Bing C. // Biol. Sci. - 2006. - Vol.361, N 1471. - P. 1237-1249.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Di Marzo V., Goparaju S. K., Wang L. et al. // Nature. - 2001. - Vol. 410. - P. 822-825.</mixed-citation><mixed-citation xml:lang="en">Di Marzo V., Goparaju S. K., Wang L. et al. // Nature. - 2001. - Vol. 410. - P. 822-825.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Pischon Т., Girman С. J., Hotamisligil G. S. et al. // J. A. M. A. - 2004. - Vol. 291. - P. 1730-1737.</mixed-citation><mixed-citation xml:lang="en">Pischon Т., Girman С. J., Hotamisligil G. S. et al. // J. A. M. A. - 2004. - Vol. 291. - P. 1730-1737.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Spranger J., Kroke A., Mohlig M. et al. // Lancet. - 2003. - Vol. 361. - P. 226-228.</mixed-citation><mixed-citation xml:lang="en">Spranger J., Kroke A., Mohlig M. et al. // Lancet. - 2003. - Vol. 361. - P. 226-228.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Kralisch S., Sommer G., Deckert C. M. et al. // Minerva Endo-crinol. - 2007. - Vol. 32. N 3. - P. 161-171.</mixed-citation><mixed-citation xml:lang="en">Kralisch S., Sommer G., Deckert C. M. et al. // Minerva Endo-crinol. - 2007. - Vol. 32. N 3. - P. 161-171.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Sun Y., Asnicar M, Smith R. G. // Neuroendocrinology. - 2007.- Vol. 83. N 3. - P. 215-228.</mixed-citation><mixed-citation xml:lang="en">Sun Y., Asnicar M, Smith R. G. // Neuroendocrinology. - 2007.- Vol. 83. N 3. - P. 215-228.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Wiedmer P., Nogueiras R., Brogtio F. et al. // Nat. Clin. Pract. Endocrinol. Metab. - 2007. - Vol. 3, N 10. - P. 705-712.</mixed-citation><mixed-citation xml:lang="en">Wiedmer P., Nogueiras R., Brogtio F. et al. // Nat. Clin. Pract. Endocrinol. Metab. - 2007. - Vol. 3, N 10. - P. 705-712.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Higgins S. C., Gueorguiev M., Korbonits M. // Ann. Med. - 2007. - Vol. 39. N 2. - P. 116-136.</mixed-citation><mixed-citation xml:lang="en">Higgins S. C., Gueorguiev M., Korbonits M. // Ann. Med. - 2007. - Vol. 39. N 2. - P. 116-136.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Whitson B. A., Leslie D. В., Kellogg T. A. et al. // J. Surg. Res. -2007. - Vol. 141, N 1. - P. 31-39.</mixed-citation><mixed-citation xml:lang="en">Whitson B. A., Leslie D. В., Kellogg T. A. et al. // J. Surg. Res. -2007. - Vol. 141, N 1. - P. 31-39.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Tucci S. A., Rogers E. K., Korbonits M, Kirkham Т. С // Br. J. Pharmacol. - 2004. - Vol. 143. - P. 520-533.</mixed-citation><mixed-citation xml:lang="en">Tucci S. A., Rogers E. K., Korbonits M, Kirkham Т. С // Br. J. Pharmacol. - 2004. - Vol. 143. - P. 520-533.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Di Marzo V., Matias I. // Nature Neurosci. - 2005. - Vol. 8, N 5. - P. 585-590.</mixed-citation><mixed-citation xml:lang="en">Di Marzo V., Matias I. // Nature Neurosci. - 2005. - Vol. 8, N 5. - P. 585-590.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Matias I., Gonthier M. P., Orlando P. et al. // J. Clin. Endo-crinol. Metab. - 2006. - Vol. 91. N 8. - P. 3171-3180.</mixed-citation><mixed-citation xml:lang="en">Matias I., Gonthier M. P., Orlando P. et al. // J. Clin. Endo-crinol. Metab. - 2006. - Vol. 91. N 8. - P. 3171-3180.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Jones J. D., Carney S. Т., Vrana К. Е. et al. // Neuropharma-cology. - 2007.</mixed-citation><mixed-citation xml:lang="en">Jones J. D., Carney S. Т., Vrana К. Е. et al. // Neuropharma-cology. - 2007.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Bequet F., Uzabiaga F., Desbazeille M. et al. // Eur. J. Neuros-ci. - 2007. - Vol.26. N 12. - P. 3458-3464.</mixed-citation><mixed-citation xml:lang="en">Bequet F., Uzabiaga F., Desbazeille M. et al. // Eur. J. Neuros-ci. - 2007. - Vol.26. N 12. - P. 3458-3464.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Pagano C, Pilon C, Calcagno A. et al. // J. Clin. Endocrinol. Metab. - 2007. - Vol.92, N 12. - P. 4810-4819.</mixed-citation><mixed-citation xml:lang="en">Pagano C, Pilon C, Calcagno A. et al. // J. Clin. Endocrinol. Metab. - 2007. - Vol.92, N 12. - P. 4810-4819.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Bensaid M., Gary-Bobo M, Esclangon A. et al. // Mol. Phar-macol. - 2003. - Vol. 63. - P. 903-914.</mixed-citation><mixed-citation xml:lang="en">Bensaid M., Gary-Bobo M, Esclangon A. et al. // Mol. Phar-macol. - 2003. - Vol. 63. - P. 903-914.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Gonthier M. P., Hoareau L., Festy F. et al. // Obesity. - 2007. -Vol. 15. N 4. - P. 837-845.</mixed-citation><mixed-citation xml:lang="en">Gonthier M. P., Hoareau L., Festy F. et al. // Obesity. - 2007. -Vol. 15. N 4. - P. 837-845.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Cota D., Marsicano G., Tschop M. et al. // J. Clin. Invest. - 2003.- Vol. 112. - P. 423-431.</mixed-citation><mixed-citation xml:lang="en">Cota D., Marsicano G., Tschop M. et al. // J. Clin. Invest. - 2003.- Vol. 112. - P. 423-431.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Jbilo O., Ravinet-Trillou C, Amone M. et al. // FASEB J. - 2005. - Vol. 19. - P. 1567-1569.</mixed-citation><mixed-citation xml:lang="en">Jbilo O., Ravinet-Trillou C, Amone M. et al. // FASEB J. - 2005. - Vol. 19. - P. 1567-1569.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Bramlage P., Bocking W., Kirch W. // Dtsch. Med. Wschr. -2005. - Bd 130. - S. 665-668.</mixed-citation><mixed-citation xml:lang="en">Bramlage P., Bocking W., Kirch W. // Dtsch. Med. Wschr. -2005. - Bd 130. - S. 665-668.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Costa В. // Br. J. Pharmacol. - 2007. - Vol. 150. - P. 535- 537.</mixed-citation><mixed-citation xml:lang="en">Costa В. // Br. J. Pharmacol. - 2007. - Vol. 150. - P. 535- 537.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Gomez A, Navarro M., Ferrer B. et al. // J. Neurosci. - 2002. -Vol. 22.-P. 9612-9617.</mixed-citation><mixed-citation xml:lang="en">Gomez A, Navarro M., Ferrer B. et al. // J. Neurosci. - 2002. -Vol. 22.-P. 9612-9617.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Landi V., Groci Т., Rinaldi-Carmona M. et al. // Eur. J. Phar-macol. - 2002. - Vol. 450. - P. 77-83.</mixed-citation><mixed-citation xml:lang="en">Landi V., Groci Т., Rinaldi-Carmona M. et al. // Eur. J. Phar-macol. - 2002. - Vol. 450. - P. 77-83.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Bramlage P., Muhlen I., Randeva H. et al. // Exp. Clin. Endo-crinol. Diabet. - 2006. - Vol. 114. - P. 75-81.</mixed-citation><mixed-citation xml:lang="en">Bramlage P., Muhlen I., Randeva H. et al. // Exp. Clin. Endo-crinol. Diabet. - 2006. - Vol. 114. - P. 75-81.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Gelfand Е. V., Cannon С. Р. // J. Am. Coll. Cardiol. - 2006. -Vol. 47.-P. 1919-1926.</mixed-citation><mixed-citation xml:lang="en">Gelfand Е. V., Cannon С. Р. // J. Am. Coll. Cardiol. - 2006. -Vol. 47.-P. 1919-1926.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Okamoto Y., Kroke A., Mohlig M. et al. // Circulation. - 2002. - Vol. 106. - P. 2767-2770.</mixed-citation><mixed-citation xml:lang="en">Okamoto Y., Kroke A., Mohlig M. et al. // Circulation. - 2002. - Vol. 106. - P. 2767-2770.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Yamauchi Т., Kamon J., Waki H. et al. // J. Biol. Chern. - 2003. - Vol. 278. - P. 2462-2468.</mixed-citation><mixed-citation xml:lang="en">Yamauchi Т., Kamon J., Waki H. et al. // J. Biol. Chern. - 2003. - Vol. 278. - P. 2462-2468.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
