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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl200955635-40</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11154</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Значение метода селективного забора крови из нижних каменистых синусов в дифференциальной диагностике АКТГ-зависимого гиперкортицизма</article-title><trans-title-group xml:lang="en"><trans-title>Significance of the method of selective blood collection from the inferior petrosal sinuses for differential diagnosis of ACTH-dependent hypercorticism</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дедов</surname><given-names>Иван Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Dedov</surname><given-names>I I</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отделение нейроэндокринологии и остеопатийдоктор мед. наук, профессор, акад. РАН и РАМН, директор</p></bio><email xlink:type="simple">dedov@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белая</surname><given-names>Жанна Евгеньевна</given-names></name><name name-style="western" xml:lang="en"><surname>Belaya</surname><given-names>Z E</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, ст. науч. сотр. отделения нейроэндокринологии и остеопатий ФГУ ЭНЦ</p></bio><email xlink:type="simple">janne-be@mtu-net.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ситкин</surname><given-names>Иван Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Sitkin</surname><given-names>I I</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отделение нейроэндокринологии и остеопатийканд. мед. наук, ст. науч. сотр. отделения рентгенодиагностики и ангиографии ФГУ ЭНЦ</p></bio><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марова</surname><given-names>Евгения Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Marova</surname><given-names>E I</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отделение нейроэндокринологии и остеопатийдоктор мед. наук, профессор, гл. науч. сотр. отделения нейроэндокринологии и остеопатий ФГУ ЭНЦ</p></bio><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пржиялковская</surname><given-names>Елена Георгиевна</given-names></name><name name-style="western" xml:lang="en"><surname>Przhiyalkovskaya</surname><given-names>E G</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отделение нейроэндокринологии и остеопатийаспирант отделения нейроэндокринологии и остеопатий ФГУ ЭНЦ</p></bio><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ремизов</surname><given-names>Олег Валерьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Remizov</surname><given-names>O V</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отделение нейроэндокринологии и остеопатийдоктор мед. наук, зав. отделением нейроэндокринологии и остеопатий ФГУ ЭНЦ</p></bio><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рожинская</surname><given-names>Людмила Яковлевна</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhinskaya</surname><given-names>L Y</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отделение нейроэндокринологии и остеопатийдоктор мед. наук, зав. отделением нейроэндокринологии и остеопатий ФГУ ЭНЦ</p></bio><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ФГУ Эндокринологический научный центр Росмедтехнологий&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinology Research Centre&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2009</year></pub-date><volume>55</volume><issue>6</issue><issue-title>ТОМ , №6 (2009)</issue-title><fpage>35</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дедов И.И., Белая Ж.Е., Ситкин И.И., Марова Е.И., Пржиялковская Е.Г., Ремизов О.В., Рожинская Л.Я., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Дедов И.И., Белая Ж.Е., Ситкин И.И., Марова Е.И., Пржиялковская Е.Г., Ремизов О.В., Рожинская Л.Я.</copyright-holder><copyright-holder xml:lang="en">Dedov I.I., Belaya Z.E., Sitkin I.I., Marova E.I., Przhiyalkovskaya E.G., Remizov O.V., Rozhinskaya L.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11154">https://www.probl-endojournals.ru/jour/article/view/11154</self-uri><abstract><p>В обзоре литературы обсуждается мировой опыт использования селективного забора крови из нижних каменистых синусов для дифференциальной диагностики АКТГ-зависимого гиперкортицизма. Описаны история развития метода, основные показания и противопоказания, информативность диагностического вмешательства, возможные причины ложноотрицательных и ложноположительных результатов, а также осложнения методики, которые когда-либо были зарегистрированы. В обзоре уделяется отдельное внимание преимуществам и недостаткам альтернативных методов забора крови, а также рассматриваются фармакологические препараты, используемые для увеличения возможностей метода.</p></abstract><trans-abstract xml:lang="en"><p>This review paper was designed to discuss the accumulated worldwide experience with selective collection of blood from the inferior petrose sinuses for the purpose of differential diagnostics of ACTH-dependent hypercorticism. The history of the development of the method is described, principal indications and contraindications to its clinical application are considered with reference to the informative value of this diagnostic tool. Possible causes of false positive and false negative results as well as complications ever reported as associated with the diagnostic procedure are discussed. Much attention is given to the comparative analysis of advantages and disadvantages of alternative techniques for blood collection and to the use of pharmaceutical agents that may increase efficiency of the method under consideration.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гиперкортицизм</kwd><kwd>АКТГ</kwd><kwd>диагностика</kwd><kwd>селективный забор крови</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypercorticism</kwd><kwd>ACTH</kwd><kwd>diagnosis</kwd><kwd>selective collection of blood</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aniszewski J. P., Young M. F., Thompson G. B. et al. // Wld J. Surg. - 2001. - Vol. 25. - P. 934-940.</mixed-citation><mixed-citation xml:lang="en">Aniszewski J. 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