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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl199844219-21</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11239</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Заболевания щитовидной железы при комплексном лечении лимфогранулематоза</article-title><trans-title-group xml:lang="en"><trans-title>Thyroid diseases in the complex treatment of lymphogranulomatosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балашов</surname><given-names>A. T.</given-names></name><name name-style="western" xml:lang="en"><surname>Balashov</surname><given-names>A. T.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мясников</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Myasnikov</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;Петрозаводский государственный университет; Республиканская больница Республики Карелия&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Petrozavodsk State University; Republican Hospital of the Republic of Karelia&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>1998</year></pub-date><pub-date pub-type="epub"><day>23</day><month>09</month><year>1998</year></pub-date><volume>44</volume><issue>2</issue><fpage>19</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Балашов A.T., Мясников А.А., 1998</copyright-statement><copyright-year>1998</copyright-year><copyright-holder xml:lang="ru">Балашов A.T., Мясников А.А.</copyright-holder><copyright-holder xml:lang="en">Balashov A.T., Myasnikov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11239">https://www.probl-endojournals.ru/jour/article/view/11239</self-uri><abstract><p>Обследовано 212 больных лимфогранулематозом в различные сроки после комплексного лечения. Гипотиреоидный статус констатирован у 19,8% больных, гиперплазия щитовидной железы — у 5,4%. Установлено отсутствие влияния полихимиотерапии на частоту выявляемых осложнений. Приведены данные о зависимости частоты и тяжести гипотиреозов, развившихся после комплексной терапии лимфогранулематоза, от возраста больных на момент облучения, введения йодсодержащих рентгеноконтрастных препаратов, дозы облучения на щитовидную железу. Определены показания к заместительной терапии тиреоидными гормонами.</p><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>A total of 212 patients with Hodgkin ’s disease were examined in different periods after multiple-modality treatment. Hypothyroid status was established in 19.8%) and thyroid hyperplasia in 5.4%o patients. Polychemotherapy did not affect the incidence of complications. The incidence and severity of hypothyrosis after multiple-modality treatment of Hodgkin ’s disease depend on the patient's age by the moment of radiation exposure, administration of iodine-containing x-ray contrast agents, and dose of the thyroid exposure. Indications for substitution therapy with thyroid hormones are defined.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лимфогранулематоз</kwd><kwd>щитовидная железа</kwd><kwd>полихимиотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lymphogranulomatosis</kwd><kwd>thyroid gland</kwd><kwd>polychemotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мясников А. А., Лившиц А. X., Менделеев И. М. // Тер. арх. — 1988. - № 5. - С. 59-62.</mixed-citation><mixed-citation xml:lang="en">Мясников А. А., Лившиц А. X., Менделеев И. 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