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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl11391</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11391</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Процесс репарации трофических язв у больных сахарным диабетом</article-title><trans-title-group xml:lang="en"><trans-title>The process of repair of trophic ulcers in patients with diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мыскина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Myskina</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Токмакова</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Tokmakova</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анциферов</surname><given-names>М. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Antsiferov</surname><given-names>M. B.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;Эндокринологический научный центр РАМН&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinology Research Center RAMS&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>15</day><month>04</month><year>2004</year></pub-date><volume>50</volume><issue>2</issue><issue-title>ТОМ 50, №2 (2004)</issue-title><fpage>34</fpage><lpage>38</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мыскина Н.А., Токмакова А.Ю., Анциферов М.Б., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Мыскина Н.А., Токмакова А.Ю., Анциферов М.Б.</copyright-holder><copyright-holder xml:lang="en">Myskina N.A., Tokmakova A.Y., Antsiferov M.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11391">https://www.probl-endojournals.ru/jour/article/view/11391</self-uri><abstract><p>В последние 30 лет отмечается резкий рост заболеваемости сахарным диабетом (СД), особенно в промышленно развитых странах, и распространенность его имеет тенденцию к дальнейшему увеличению [<xref ref-type="bibr" rid="cit3">3</xref>]. Основной причиной инвалидизации и гибели больных являются поздние осложнения этого заболевания. Среди них особенно важно вы-делить развивающийся синдром диабетической стопы (СДС), который определяется как инфекция, язва и/или деструкция глубоких тканей, связанная с неврологическими нарушениями и снижением магистрального кровотока в артериях нижних конечностей различной степени тяжести (Международное соглашение по диабетической стопе, Нидерланды, 1999 г.)</p></abstract><trans-abstract xml:lang="en"><p>In the last 30 years, there has been a sharp increase in the incidence of diabetes mellitus (DM), especially in industrialized countries, and its prevalence tends to further increase [<xref ref-type="bibr" rid="cit3">3</xref>]. The main cause of disability and death of patients are late complications of this disease. Among them, it is especially important to identify developing diabetic foot syndrome (DFS), which is defined as infection, ulcer and / or destruction of deep tissues, associated with neurological disorders and decreased main blood flow in the arteries of the lower extremities of varying degrees severity (International Diabetic Foot Agreement, Netherlands, 1999)</p></trans-abstract><kwd-group xml:lang="ru"><kwd>процесс репарации</kwd><kwd>трофические язвы</kwd><kwd>сахарный диабет</kwd></kwd-group><kwd-group xml:lang="en"><kwd>repair process</kwd><kwd>trophic ulcers</kwd><kwd>diabetes mellitus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аничков Н. Н., Волкова К. Г., Гаршин В. Г. // Морфология заживления ран. — М., 1951. — С. 98-127.</mixed-citation><mixed-citation xml:lang="en">Аничков Н. Н., Волкова К. Г., Гаршин В. 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