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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl11621</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11621</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В помощь практикующему врачу</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>For practitioners</subject></subj-group></article-categories><title-group><article-title>Альдостерон и функция сердечно-сосудистой системы&#13;
(к 50-летию открытия альдостерона)</article-title><trans-title-group xml:lang="en"><trans-title>Aldosterone and cardiovascular function&#13;
(to the 50th anniversary of the discovery of aldosterone)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гончаров</surname><given-names>П. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Goncharov</surname><given-names>P. P.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;ГУ Эндокринологический научный центр РАМН&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinological Research Center of RAMS&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2004</year></pub-date><volume>50</volume><issue>6</issue><issue-title>ТОМ 50, №6 (2004)</issue-title><fpage>29</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гончаров П.П., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Гончаров П.П.</copyright-holder><copyright-holder xml:lang="en">Goncharov P.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11621">https://www.probl-endojournals.ru/jour/article/view/11621</self-uri><abstract><p>В работе Т. Addison [<xref ref-type="bibr" rid="cit3">3</xref>], опубликованной за 100 лет до открытия альдостерона (1954 г.), описывался синдром с летальным исходом, обусловленный де­струкцией коры надпочечников, вызванной тубер­кулезным процессом. Она явилась стимулом для интенсивного изучения физиологии адреналовых желез. Конец 30-х годов увенчался принципиаль­ным успехом: из коркового слоя надпочечников была выделена глюкокортикоидная группа стерои­дов и расшифрована их химическая структура. Признания заслуживает прежде всего швейцарская группа ученых — проф. Reichstein и его сотрудники Wettstein, Neher и Euw. Группа проф. Kendall (США) также успешно провела аналогичную рабо­ту и опубликовала аналогичные результаты не­сколько позднее.</p></abstract><trans-abstract xml:lang="en"><p>T. Addison [<xref ref-type="bibr" rid="cit3">3</xref>], published 100 years before the discovery of aldosterone (1954), described a fatal syndrome caused by destruction of the adrenal cortex caused by the tuberculosis process. It was an incentive for an intensive study of the physiology of the adrenal glands. The end of the 30s was crowned with fundamental success: a glucocorticoid group of steroids was isolated from the cortical layer of the adrenal glands and their chemical structure was deciphered. Recognition deserves first of all the Swiss group of scientists - prof. Reichstein and its employees Wettstein, Neher and Euw. Group prof. Kendall (USA) also successfully carried out similar work and published similar results a little later.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Альдостерон</kwd><kwd>сердечно-сосудистая система</kwd><kwd>физиология адреналовых желез</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Aldosterone</kwd><kwd>the cardiovascular system</kwd><kwd>physiology of adrenal glands</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гончаров Н. ГГ, Колесникова Г. С., Тодуа Т. И. и др. // Пробл. эндокринол. - 2001. - № 5. - С. 24-28.</mixed-citation><mixed-citation xml:lang="en">Гончаров Н. ГГ, Колесникова Г. С., Тодуа Т. И. и др. // Пробл. эндокринол. - 2001. - № 5. - С. 24-28.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гончаров Н. П., Колесникова Г. 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