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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl11666</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11666</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая эндокринология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical endocrinology</subject></subj-group></article-categories><title-group><article-title>Содержание соматотропного гормона и кортизола при проведении инсулинового теста у участников ликвидации аварии на Чернобыльской АЭС</article-title><trans-title-group xml:lang="en"><trans-title>The content of growth hormone and cortisol during an insulin test in participants in the liquidation of the Chernobyl accident</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арапова</surname><given-names>С. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Arapova</surname><given-names>S. D.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Молитвословова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Molitvoslovova</surname><given-names>N. N.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колесникова</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolesnikova</surname><given-names>G. S.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гончаров</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Goncharov</surname><given-names>N. P.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Marova</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панкова</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pankova</surname><given-names>S. S.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;Эндокринологический научный центр РАМН&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinology Research Center RAMS&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>1998</year></pub-date><pub-date pub-type="epub"><day>01</day><month>10</month><year>1998</year></pub-date><volume>44</volume><issue>6</issue><issue-title>ТОМ 44, №6 (1998)</issue-title><fpage>30</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Арапова С.Д., Молитвословова Н.Н., Колесникова Г.С., Гончаров Н.П., Марова Е.И., Панкова С.С., 1998</copyright-statement><copyright-year>1998</copyright-year><copyright-holder xml:lang="ru">Арапова С.Д., Молитвословова Н.Н., Колесникова Г.С., Гончаров Н.П., Марова Е.И., Панкова С.С.</copyright-holder><copyright-holder xml:lang="en">Arapova S.D., Molitvoslovova N.N., Kolesnikova G.S., Goncharov N.P., Marova E.I., Pankova S.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11666">https://www.probl-endojournals.ru/jour/article/view/11666</self-uri><abstract><p>Проведено изучение гипоталамо-гипофизарно-надпочечниковой системы у 25 участников ликвидации последствий аварии на Чернобыльской АЭС (ликвидаторов) с помощью пробы с инсулином и определения секреции соматотропного гормона (СТГ) и кортизола во время теста. У всех ликвидаторов введение инсулина вызывало достоверное снижение уровня сахара в крови. Исходные уровни кортизола и СТГ были в пределах нормальных значений. Во время пробы у обследованных лиц не отмечено достоверного повышения уровня кортизола. У 94% ликвидаторов получен выброс СТГ в ответ на гипогликемию, но эта реакция была значительно менее выражена, чем у лиц контрольной группы. Предварительные данные указывают на наличие недостаточной секреции СТГ и отсутствие достоверного повышения уровня кортизола. Таким образом, у ликвидаторов имеются нарушения гипоталамо-гипофизарной системы, указывающие на снижение адаптационных возможностей организма.</p><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>The hypothalamic-pituitary-adrenal system was studied in 25 participants in the aftermath of the Chernobyl accident (liquidators) using a test with insulin and determining the secretion of growth hormone (STH) and cortisol during the test. In all liquidators, insulin administration caused a significant decrease in blood sugar. Baseline cortisol and STH levels were within normal limits. During the test, the examined individuals did not show a significant increase in the level of cortisol. 94% of the liquidators received a release of STH in response to hypoglycemia, but this reaction was significantly less pronounced than in individuals in the control group. Preliminary data indicate the presence of insufficient secretion of GH and the absence of a significant increase in cortisol levels. Thus, the liquidators have violations of the hypothalamic-pituitary system, indicating a decrease in the adaptive capacity of the body.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>кортизол</kwd><kwd>соматотропный гормон</kwd><kwd>Чернобыльская АЭС</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cortisol</kwd><kwd>growth hormone</kwd><kwd>Chernobyl NPP</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов В. И., Дедов И. И., Степаненко В. Ф. // Радиационная эндокринология. — М., 1993. — С. 72.</mixed-citation><mixed-citation xml:lang="en">Дедов В. И., Дедов И. И., Степаненко В. Ф. // Радиационная эндокринология. — М., 1993. — С. 72.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Марова Е. И., Арапова С. 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