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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl11864</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11864</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Эпифиз: современные данные о физиологии и патологии</article-title><trans-title-group xml:lang="en"><trans-title>Epiphysis: current data on physiology and pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семичева</surname><given-names>T. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Semicheva</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарибашвили</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Garibashvili</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>&lt;p&gt;Эндокринологический научный центр РАМН&lt;/p&gt;</institution><country>Россия</country></aff><aff xml:lang="en"><institution>&lt;p&gt;Endocrinology Research Center RAMS&lt;/p&gt;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2000</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2000</year></pub-date><volume>46</volume><issue>4</issue><issue-title>ТОМ 46, №4 (2000)</issue-title><fpage>38</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семичева T.В., Гарибашвили А.Ю., 2000</copyright-statement><copyright-year>2000</copyright-year><copyright-holder xml:lang="ru">Семичева T.В., Гарибашвили А.Ю.</copyright-holder><copyright-holder xml:lang="en">Semicheva T.V., Garibashvili A.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11864">https://www.probl-endojournals.ru/jour/article/view/11864</self-uri><abstract><p>На сегодняшний день эпифиз является одной из самых "титулованных" желез внутренней секреции, но интерес к нему не убавился, а продолжает возрастать. Организован и работает "Мелатониновый клуб", издаются "Jounal of Pineal Research", "Advances in Pineal Research", "European Pineal Society News". Бурное развитие хронобиологии привело к устранению ведущей роли эпифиза и его гормона мелатонина в реализации циркадных, сезонных и годовых ритмов самых разных функциональных систем организма [<xref ref-type="bibr" rid="cit1">1</xref>]. Несмотря на это, количество современной литературы на русском языке, посвященной не каким-то отдельным вопросам, а эпифизу и его патологии в целом, весьма ограничено.</p></abstract><trans-abstract xml:lang="en"><p>Today the pineal gland is one of the most “titled” endocrine glands, but interest in it has not diminished, but continues to increase. A Melatonin Club has been organized and operates, and Jounal of Pineal Research, Advances in Pineal Research, and European Pineal Society News are published. The rapid development of chronobiology led to the elimination of the leading role of the pineal gland and its hormone melatonin in the implementation of circadian, seasonal and annual rhythms of the most diverse functional systems of the body [<xref ref-type="bibr" rid="cit1">1</xref>]. Despite this, the amount of modern literature in Russian, devoted not to some particular issues, but to the pineal gland and its pathology as a whole, is very limited.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпифиз</kwd><kwd>хронобиология</kwd><kwd>функциональные системы организма</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pineal gland</kwd><kwd>chronobiology</kwd><kwd>functional systems of the body</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Анисимов В. Н. // Пробл. эндокринол. — 1996. — № 6. — С. 40-41.</mixed-citation><mixed-citation xml:lang="en">Анисимов В. 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