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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl11881</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-11881</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В помощь практикующему врачу</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>For practitioners</subject></subj-group></article-categories><title-group><article-title>Аденома щитовидной железы у пациентки с болезнью Иценко—Кушинга</article-title><trans-title-group xml:lang="en"><trans-title>Thyroid adenoma in a patient with Itsenko-Cushing's disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шилина</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilina</surname><given-names>S. Yu.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шилин</surname><given-names>Д. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilin</surname><given-names>D. E.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бронштейн</surname><given-names>М. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Bronstein</surname><given-names>M. E.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривская</surname><given-names>Л. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivskaya</surname><given-names>L. K.</given-names></name></name-alternatives><email xlink:type="simple">probl@endojournals.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Консультативно-диагностический центр ГКБ № 15; Российская медицинская академия последипломного образования Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Consultative and diagnostic center GKB number 15; Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2000</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2000</year></pub-date><volume>46</volume><issue>6</issue><issue-title>ТОМ 46, №6 (2000)</issue-title><fpage>34</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шилина С.Ю., Шилин Д.Е., Бронштейн М.Э., Кривская Л.К., 2000</copyright-statement><copyright-year>2000</copyright-year><copyright-holder xml:lang="ru">Шилина С.Ю., Шилин Д.Е., Бронштейн М.Э., Кривская Л.К.</copyright-holder><copyright-holder xml:lang="en">Shilina S.Y., Shilin D.E., Bronstein M.E., Krivskaya L.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/11881">https://www.probl-endojournals.ru/jour/article/view/11881</self-uri><abstract><p>В литературе имеются немногочисленные наблюдения, указывающие на повышенную частоту узловой патологии щитовидной железы (ЩЖ) при синдроме тотального гиперкортицизма [3,6, 8—13, 15—17]. По некоторым сведениям, пальпируемые образования и нодулярные изменения при УЗИ этого органа обнаруживаются у пациентов с болезнью Иценко—Кушинга в 2,5—3 раза чаще, чем в популяции (10% против 4% [<xref ref-type="bibr" rid="cit14">14</xref>] и 60% против 20% [<xref ref-type="bibr" rid="cit7">7</xref>] соответственно). При этом в клинически однотипных случаях сочетания "узел ЩЖ + гиперкортицизм" морфологический характер патологии тиреоидной и гипофизарнонадпочечниковой системы отличается выраженным полиморфизмом.</p></abstract><trans-abstract xml:lang="en"><p>There are few observations in the literature that indicate an increased frequency of thyroid nodular pathology (thyroid gland) with total hypercorticism syndrome [3,6, 8-13, 15-17]. According to some reports, palpable formations and nodular changes in ultrasound of this organ are found in patients with Itsenko-Cushing's disease 2.5-3 times more often than in the population (10% versus 4% [<xref ref-type="bibr" rid="cit14">14</xref>] and 60% versus 20% [7 ] respectively). Moreover, in clinically similar cases of the combination "thyroid gland + hypercorticism", the morphological nature of the pathology of the thyroid and pituitary-adrenal system is characterized by pronounced polymorphism.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аденома щитовидной железы</kwd><kwd>гиперкортицизм</kwd><kwd>болезнь Иценко-Кушинга</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thyroid adenoma</kwd><kwd>hypercorticism</kwd><kwd>Itsenko-Cushing's disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Калинин А. П., Ермулович Я. В., Фикс А. 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