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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl12686</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-12686</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Нарушения углеводного обмена</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Carbohidrates metabolism disturbancies</subject></subj-group></article-categories><title-group><article-title>Подготовка пациента с сахарным диабетом 1 типа на заместительной почечной терапии диализом к трансплантации почки</article-title><trans-title-group xml:lang="en"><trans-title>Preparation of the dialysis patient with type 1 diabetes mellitus for kidney transplantation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2257-3224</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартынов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Martynov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мартынов Сергей Андреевич - доктор медицинских наук.117036, Москва, ул. Дм. Ульянова, д. 11.eLibrary SPIN: 6231-2450</p></bio><bio xml:lang="en"><p>Sergey A. Martynov - MD, PhD.11 Dm Ulyanova str., 117036, Moscow.eLibrary SPIN: 6231-2450</p></bio><email xlink:type="simple">smartynov@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0296-4933</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Северина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Severina</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Северина Анастасия Сергеевна - кандидат медицинских наук, ведущий научный сотрудник.117036, Москва, ул. Дм. Ульянова, д. 11.eLibrary SPIN: 3182-9510</p></bio><bio xml:lang="en"><p>Anastasia S. Severina - MD, PhD, leading research associate.11 Dm Ulyanova str., 117036, Moscow.eLibrary SPIN: 3182-9510</p></bio><email xlink:type="simple">ansev1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6783-4200</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларина</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Larina</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ларина Ирина Игоревна - научный сотрудник.117036, Москва, ул. Дм. Ульянова, д. 11.eLibrary SPIN: 1220-6080</p></bio><bio xml:lang="en"><p>Irina I. Larina - MD, research associate.11 Dm Ulyanova str., 117036, Moscow.eLibrary SPIN: 1220-6080</p></bio><email xlink:type="simple">rina.larina1993@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3433-0142</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамхалова</surname><given-names>М. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamhalova</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шамхалова Минара Шамхаловна - доктор медицинских наук.117036, Москва, ул. Дм. Ульянова, д. 11.eLibrary SPIN: 4942-5481</p></bio><bio xml:lang="en"><p>Minara S. Shamhalova - MD, PhD.11 Dm Ulyanova str., 117036, Moscow.eLibrary SPIN: 4942-5481</p></bio><email xlink:type="simple">shamkhalova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7358-3364</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арзуманов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Arzumanov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Арзуманов Сергей Викторович - доктор медицинских наук.Москва.eLibrary SPIN: 8317-3723</p></bio><bio xml:lang="en"><p>Sergey V Arzumanov - MD, PhD.Moscow.eLibrary SPIN: 8317-3723</p></bio><email xlink:type="simple">kidneytranspl@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9019-9567</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пинчук</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pinchuk</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пинчук Алексей Валерьевич - доктор медицинских наук.Москва.eLibrary SPIN: 8875-2456</p></bio><bio xml:lang="en"><p>Aleksey V. Pinchuk - MD, PhD.Moscow.eLibrary SPIN: 8875-2456</p></bio><email xlink:type="simple">avpin@rambler.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5057-127X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестакова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шестакова Марина Владимировна - доктор медицинских наук, профессор, академик РАН.117036, Москва, ул. Дм. Ульянова, д. 11.eLibrary SPIN: 7584-7015</p></bio><bio xml:lang="en"><p>Marina V. Shestakova - MD, PhD, Professor.11 Dm Ulyanova str., 117036, Moscow.eLibrary SPIN: 7584-7015</p></bio><email xlink:type="simple">nephro@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр эндокринологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт урологии и интервенционной радиологии им. Н.А. Лопаткина — филиал ­Национального медицинского исследовательского центра радиологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.A. Lopatkin Research Institute of Urology and Interventional Radiology — branch of the National Medical Radiological Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sklifosovsky Research Institute for Emergency Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2020</year></pub-date><volume>66</volume><issue>6</issue><fpage>18</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мартынов С.А., Северина А.С., Ларина И.И., Шамхалова М.Ш., Арзуманов С.В., Пинчук А.В., Шестакова М.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Мартынов С.А., Северина А.С., Ларина И.И., Шамхалова М.Ш., Арзуманов С.В., Пинчук А.В., Шестакова М.В.</copyright-holder><copyright-holder xml:lang="en">Martynov S.A., Severina A.S., Larina I.I., Shamhalova M.S., Arzumanov S.V., Pinchuk A.V., Shestakova M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/12686">https://www.probl-endojournals.ru/jour/article/view/12686</self-uri><abstract><p>Трансплантация почки (ТП) считается уникальным методом заместительной почечной терапии, позволяющим пациентам с сахарным диабетом 1 типа (СД1) с диабетической нефропатией на терминальной стадии почечной недостаточности, находящимся на лечении программным диализом (перитонеальный диализ и гемодиализ), повысить качество жизни и ее продолжительность. В настоящее время создание и внедрение инновационных технологий по управлению диабетом и современных иммуносупрессантов позволяют достигать лучших результатов реабилитации пациента с СД1 после пересадки почки, особенно в короткие сроки после начала диализной терапии. Для снижения ранних и поздних осложнений после ТП важнейшее значение имеет предтрансплантационное обследование пациента с СД1 перед включением его в лист ожидания. Подготовка к пересадке почки охватывает такие мероприятия, как эффективный контроль гликемии, проведение адекватной диализной терапии, диагностика других осложнений диабета и различных сопутствующих заболеваний, особенно сердечно-сосудистой системы, тяжесть которых является определяющим фактором в принятии решения о перспективе ТП. Кроме того, выявление и лечение любого инфекционного процесса, своевременная вакцинопрофилактика, тщательный онкопоиск представляют основу программы подготовки пациента к пересадке почки, обеспечивающей наилучшую выживаемость почечного трансплантата и реципиента.</p></abstract><trans-abstract xml:lang="en"><p>Kidney transplantation is unique method of renal replacement therapy, allowing to improve quality and duration of life for patients with diabetes mellitus type 1 (DM1) and end-stage renal disease (ESRD) on dialysis therapy. Recently using of innovation technologies for diabetes management and modern immunosuppression enable achieving better results of posttransplant rehabilitation for patients with DM1, especially if kidney transplantation is performed early after initiation of dialysis. Detailed examination of patient with DM1 before potential kidney transplantation is very important to reduce of early and late postoperative complications. Kidney transplantation preparation includes effective glycemic control, adequate dialysis therapy, treatment of diabetes and ESRD complications and concomitant conditions, especially cardiovascular diseases, accounting for kidney transplantation perspective. Furthermore, diagnostics and treatment of any infectious process, timely vaccination, cancer screening are basic approaches of kidney transplantation preparation program, providing the best survival rate of kidney graft and patient.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трансплантация почки</kwd><kwd>сахарный диабет 1 типа</kwd><kwd>контроль гликемии</kwd><kwd>сердечно-сосудистый риск</kwd><kwd>инфекция</kwd><kwd>опухоль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>kidney transplantation</kwd><kwd>diabetes mellitus type 1</kwd><kwd>glycaemia control</kwd><kwd>cardiovascular risk</kwd><kwd>infection</kwd><kwd>cancer</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа проведена в рамках выполнения Государственного задания Минздрава России (АААА-А20-120011790181-1).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">International Diabetes Federation. 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