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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl12793</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-12793</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая эндокринология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical endocrinology</subject></subj-group></article-categories><title-group><article-title>Йододефицитные заболевания: текущее состояние проблемы в Брянской области</article-title><trans-title-group xml:lang="en"><trans-title>Iodine Deficiency Disorders: Current State of the Problem in the Bryansk Region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8520-8702</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трошина Екатерина Анатольевна, д.м.н., член-корр. РАН, профессор</p><p>eLibrary SPIN: 8821-8990</p><p>Москва</p></bio><bio xml:lang="en"><p>Ekaterina A. Troshina, MD, PhD, Professor</p><p>eLibrary SPIN: 8821-8990</p><p>Moscow</p></bio><email xlink:type="simple">troshina@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3805-7574</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маколина</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Makolina</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маколина Наталья Павловна, н.с.</p><p>eLibrary SPIN: 7210-9512</p><p>Москва</p></bio><bio xml:lang="en"><p>Natalya P. Makolina, MD</p><p>eLibrary SPIN: 7210-9512</p><p>Moscow</p></bio><email xlink:type="simple">makolina.natalia@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7960-8315</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сенюшкина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Senyushkina</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сенюшкина Евгения Семеновна, научный сотрудник</p><p>Москва, ул. Дм. Ульянова, д. 1</p><p>eLibrary SPIN: 4250-5123</p></bio><bio xml:lang="en"><p>Evgeniya S. Senyushkina, MD</p><p>11 Dm. Ulyanova street, 117036 Moscow</p><p>eLibrary SPIN: 4250-5123</p></bio><email xlink:type="simple">EvgeniyaSenyushkina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8303-3825</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никанкина</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikankina</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никанкина Лариса Вячеславовна, к.м.н.</p><p>eLibrary SPIN: 2794-0008</p></bio><bio xml:lang="en"><p>Larisa V. Nikankina, PhD</p><p>eLibrary SPIN: 2794-0008</p><p>Moscow</p></bio><email xlink:type="simple">nikankina.larisa@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7321-9052</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малышева</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Malysheva</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малышева Наталья Михайловна, к.б.н.</p><p>eLibrary SPIN: 5793-2550</p><p>Москва</p></bio><bio xml:lang="en"><p>Natalia M. Malysheva, PhD</p><p>eLibrary SPIN: 5793-2550</p><p>Moscow</p></bio><email xlink:type="simple">Malysheva.Natalya@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9667-9457</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фетисова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fetisova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фетисова Алла Валериановна</p><p>eLibrary SPIN: 3420-7859</p><p>Брянск</p></bio><bio xml:lang="en"><p>Alla V. Fetisova, MD</p><p>eLibrary SPIN: 3420-7859</p><p>Bryansk</p></bio><email xlink:type="simple">Lihva5@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр эндокринологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Департамент здравоохранения Брянской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Health of the Bryansk Region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>03</day><month>08</month><year>2021</year></pub-date><volume>67</volume><issue>4</issue><fpage>84</fpage><lpage>93</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трошина Е.А., Маколина Н.П., Сенюшкина Е.С., Никанкина Л.В., Малышева Н.М., Фетисова А.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Трошина Е.А., Маколина Н.П., Сенюшкина Е.С., Никанкина Л.В., Малышева Н.М., Фетисова А.В.</copyright-holder><copyright-holder xml:lang="en">Troshina E.A., Makolina N.P., Senyushkina E.S., Nikankina L.V., Malysheva N.M., Fetisova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/12793">https://www.probl-endojournals.ru/jour/article/view/12793</self-uri><abstract><p>ОБОСНОВАНИЕ. Брянская область относится к регионам Российской Федерации, в наибольшей степени пострадавшим в результате аварии на Чернобыльской атомной электростанции 26 апреля 1986 г. В условиях хронического некомпенсированного дефицита йода в питании в первые месяцы после аварии происходил активный захват радиоактивного йода тканью щитовидной железы (ЩЖ), что неизбежно реализовалось в росте заболеваний ЩЖ у населения в последующем. В статье представлены результаты проведенного в мае 2021 г. специалистами ФГБУ «НМИЦ эндокринологии» Минздрава России контрольно-эпидемиологического исследования, направленного на оценку современного состояния йодной обеспеченности населения Брянской области.ЦЕЛЬ. Оценка йодной обеспеченности населения Брянской области.МАТЕРИАЛЫ И МЕТОДЫ. Исследование проводилось в общеобразовательных школах трех районов Брянской области (гг. Брянск, Новозыбков и Клинцы). В исследование были включены 337 школьников допубертатного возраста (8–10 лет), всем детям выполнено: измерение роста и веса непосредственно перед осмотром врача, включавшим пальпацию ЩЖ; ультразвуковое исследование (УЗИ) ЩЖ с использованием портативного аппарата LOGIQe (China) с мультичастотным линейным датчиком 10–15 МГц; определение концентрации йода в разовых порциях мочи. Качественное исследование на наличие йодата калия в образцах пищевой поваренной соли (n=344), полученной из домохозяйств и школьных столовых, осуществлялось на месте экспресс-методом.РЕЗУЛЬТАТЫ. По результатам обследования 337 детей допубертатного возраста медианная концентрация йода в моче составляет 98,3 мкг/л (диапазон от 91,5 до 111,5 мкг/л, доля проб мочи со сниженной концентрацией йода составила 50,1%). По данным УЗИ ЩЖ у 17% обследованных детей был выявлен диффузный зоб, частота которого варьировала от 9,4 до 29% по областям исследования. Доля йодированной соли, употребляемой в семьях школьников районов исследования, составила 17,8% (диапазон значений от 15,6 до 19%), что свидетельствует о крайне низком уровне потребления йодированной соли населением. Вся соль, используемая для приготовления пищи в школьных столовых районов исследования, была йодированной, что подтверждает соблюдение требований СанПиН 2.4.5.2409-08.ЗАКЛЮЧЕНИЕ. Несмотря на активное проведение в Брянской области различных профилактических программ йододефицитных заболеваний и социальных мероприятий по пропаганде использования йодированной соли, в условиях отсутствия по настоящее время массовой профилактики при помощи йодированной соли, следует констатировать их неудовлетворительные результаты.</p></abstract><trans-abstract xml:lang="en"><p>BACKGROUND: The Bryansk region is one of the regions of the Russian Federation most affected by the accident at the Chernobyl nuclear power plant on April 26, 1986.In the conditions of a chronic uncompensated deficiency of iodine in the diet in the first months after the accident, an active seizure of radioactive iodine by the thyroid tissue took place, which inevitably resulted in an increase in thyroid diseases from the population in the future. The article presents the results of a control and epidemiological study carried out in May 2021 by specialists of the National Medical Research Center of Endocrinology of the Ministry of Health of Russia, aimed at assessing the current state of iodine provision in the population of the Bryansk region.AIM: Assessment of iodine supply of the population of the Bryansk region.MATERIALS AND METHODS: The research was carried out in secondary schools of three districts of the Bryansk region (Bryansk, Novozybkov and Klintsy).The study included 337 schoolchildren of pre-pubertal age (8–10 years), all children underwent: measurement of height and weight immediately before the doctor’s examination, which included palpation of the thyroid gland (thyroid gland); Thyroid ultrasound using a portable device LOGIQe (China) with a multi-frequency linear transducer 10–15 MHz; determination of iodine concentration in single portions of urine. A qualitative study for the presence of potassium iodate in samples of table salt (n = 344) obtained from households and school canteens was carried out on the spot using the express method.RESULTS: According to the results of a survey of 337 pre-pubertal children, the median urinary iodine concentration (mCIM) is 98.3 μg / L (range from 91.5 to 111.5 μg / L, the proportion of urine samples with a reduced iodine concentration was 50.1%). According to the ultrasound of the thyroid gland, 17% of the examined children had diffuse goiter, the frequency of which varied from 9.4 to 29% in the areas of study. The share of iodized salt consumed in the families of schoolchildren in the study areas was 17.8% (values range from 15.6 to 19%), which indicates an extremely low level of iodized salt consumption by the population. All salt used for cooking in school canteen areas of the study was iodized, which confirms compliance with the requirements of SanPiN 2.4.5.2409–08.CONCLUSION: Despite the active implementation in the Bryansk region of various preventive programs of IDD and social activities to promote the use of iodized salt, in the absence of mass prevention with the help of iodized salt to date, their unsatisfactory results should be noted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>йодный дефицит</kwd><kwd>зоб</kwd><kwd>йододефицитные заболевания</kwd><kwd>йодированная соль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>iodine deficiency</kwd><kwd>goiter</kwd><kwd>iodine deficiency diseases</kwd><kwd>iodized salt</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено при финансовой поддержке государственного задания: «Эпидемиологические и молекулярно-клеточные характеристики опухолевых, аутоиммунных и йододефицитных тиреопатий как основа профилактики осложнений и персонализации лечения», Рег. № АААА-А20-120011790180-4.</funding-statement></funding-group></article-meta></front><back><ref-list><ref id="cit1"><mixed-citation publication-type="commun" publication-format="web"><name><surname>Dedov</surname> <given-names>I.I.</given-names></name> <article-title>Ioddefitsitnye zabolevaniya v Rossiiskoi Federatsii</article-title> / Pod red. 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