problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl13198problendo-13198Research ArticleРепродуктивная эндокринологияReproductive EndocrinologyРоль эстриола в лечении атрофии слизистой оболочки нижних отделов мочеполового тракта в постменопаузеThe role of estriol in the treatment of atrophy of the mucous membrane of the lower genitourinary tract in postmenopausal womenhttps://orcid.org/0000-0001-8425-0020АндрееваЕ. Н.AndreevaE. N.

Андреева Елена Николаевна - д.м.н.

117036, Москва, ул. Дмитрия Ульянова, д. 11

SPIN-код: 1239-2937

Elena N. Andreeva - MD, PhD, DSc

11 Dm. Ulyanov str., Moscow, 117036

SPIN-код: 1239-2937

endogin@mail.ruhttps://orcid.org/0000-0001-7177-0254ШереметьеваЕ. В.SheremetyevaE. V.

Шереметьева Екатерина Викторовна - к.м.н., вед.научн. сотрудник Отделения эндокринной гинекологии Института репродуктивной медицины

117036, Москва, ул. Дмитрия Ульянова, д. 11

SPIN-код: 9413-5136

Ekaterina V. Sheremetyeva - MD, PhD

11 Dm. Ulyanov str., Moscow, 117036

SPIN-код: 9413-5136

s1981k@yandex.ruНациональный медицинский исследовательский центр эндокринологии; Московский медицинский медико-стоматологический университет им. А.И. ЕвдокимоваРоссияEndocrinology Research Centre; Evdokimov Moscow State University of Medicine and DentistryRussian FederationНациональный медицинский исследовательский центр эндокринологииРоссияEndocrinology Research CentreRussian Federation202220122022686157163Copyright © Андреева Е.Н., Шереметьева Е.В., 20222022Андреева Е.Н., Шереметьева Е.В.Andreeva E.N., Sheremetyeva E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/13198

Исследования последних десятилетий показывают неуклонный рост средней продолжительности жизни человека, и женщины в частности. Всемирная организация здравоохранения прогнозирует к 2030 г. четырехкратное увеличение численности женщин старше 70 лет, при этом многие из них в возрасте после 45 лет могут столкнуться с проблемами климактерического периода. Климактерий является физиологическим состоянием в жизни женщины, в течение которого на фоне возрастных изменений происходят постепенное снижение и выключение функции яичников и прекращение выработки эстрогенов. Генитоуринарный синдром встречается у каждой третьей женщины в этом периоде. Эстриол — основной эстроген, который таргетно решает проблемы, обусловленные эстрогенной недостаточностью: диспареунии, сухости и зуда во влагалище и нижних отделах мочеполового тракта, нарушения мочевыведения, умеренного недержания мочи, а также рецидивирующего вульвовагинита и цистита. Вульвовагинальная дистрофия у женщин старшей возрастной группы — это мультидисциплинарная проблема на стыке гинекологии, урологии и дерматологии, которая может и должна быть решена для предотвращения более тяжелой гинекологической и урологической патологий.

Studies of recent decades show a steady increase in the average life expectancy of a person, and women in particular. The World Health Organization predicts a four-fold increase in the number of women over 70 by 2030, and many of them over the age of 45 may face menopausal problems. Menopause is a physiological state in a woman’s life, during which, against the background of age-related changes, there is a gradual decrease and shutdown of ovarian function and the cessation of estrogen production. Genitourinary syndrome occurs in every third woman in this period. Estriol is the main estrogen that specifically addresses problems associated with estrogen deficiency: dyspareunia, dryness and itching in the vagina and lower genitourinary tract, urinary incontinence, moderate urinary incontinence, and recurrent vulvovaginitis and cystitis. Vulvovaginal dystrophy in women of the older age group is a multidisciplinary problem at the intersection of gynecology, urology and dermatology, which can and should be solved to prevent more severe gynecological and urological pathologies.

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The authors declare that there are no conflicts of interest present.