problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl13389problendo-13389Research ArticleБолезни костной и жировой тканиBones & Adipose tissues diseasesКогнитивные расстройства у пациентов с ожирением и нарушением углеводного обмена (дисгликемией)Cognitive impairment in patients with obesity and impaired carbohydrate metabolism (dysglycemia)https://orcid.org/0000-0002-0327-4619ДзгоеваФ. Х.DzgoevaF. Kh.

Дзгоева Фатима Хаджимуратовна - к.м.н.

Москва

Fatima Kh. Dzgoeva - MD, PhD.

Moscow

fatima.dzgoeva@gmail.comhttps://orcid.org/0000-0002-3638-6094ЕкушеваЕ. В.EkushevaE. V.

Екушева Евгения Викторовна - д.м.н., профессор.

Москва, Белгород

MD, PhD, Professor.

Moscow, Belgorod

ekushevaev@mail.ruhttps://orcid.org/0000-0002-8070-2322ДемидоваВ. В.DemidovaV. V.

Демидова Виктория Викторовна

117036, Москва, ул. Дм.Ульянова, д. 11

Viktoria Demidova

11 Dm.Ulyanova street, 117036 Moscow

vicky-quikky@mail.ruНациональный медицинский исследовательский центр эндокринологииРоссияEndocrinology Research CentreRussian FederationФедеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий Федерального медико-биологического агентства; Белгородский государственный национальный исследовательский университетРоссияAcademy of Postgraduate Education of the Federal Research and Clinical Centre for Specialized Medical Care and Medical Technologies; Belgorod State National Research UniversityRussian Federation2024160920247047583Copyright © Дзгоева Ф.Х., Екушева Е.В., Демидова В.В., 20242024Дзгоева Ф.Х., Екушева Е.В., Демидова В.В.Dzgoeva F.K., Ekusheva E.V., Demidova V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/13389

Ожирение — это хроническое заболевание, гетерогенное по этиологии и клиническим проявлениям, прогрессирующее при естественном течении болезни и характеризующееся избыточным отложением жировой массы в организме. Данное патологическое состояние в последние годы приняло масштаб глобальной эпидемии, размеры которой неуклонно увеличиваются, затрагивая в настоящее время более 2 миллиардов человек во всем мире. Ввиду своей неоднородности, ожирение оказывает негативное влияние на работу практически всех органов и систем организма, способствуя возникновению дополнительных сопутствующих заболеваний и патологических состояний, существенно ухудшающих качество жизни этих пациентов. Так, давно известна тесная взаимосвязь между сахарным диабетом 2 типа и когнитивными нарушениями, как и с рядом других соматических заболеваний: ишемической болезнью сердца, атеросклерозом, неалкогольной жировой болезнью печени, дислипидемией, злокачественными новообразованиями и другими ассоциированными патологическими состояниями на фоне избыточной массы тела и ожирения.

В настоящее время весьма актуальной является проблема возникновения когнитивных нарушений у пациентов с избыточной массой тела или изменением гликемического профиля ввиду высокой распространенности и недостаточной изученности данного вопроса.

Obesity is a chronic disease, heterogeneous in etiology and clinical manifestations, progressing with a natural course, characterized by excessive deposition of fat mass in the body. This pathological condition has taken on the scale of a global epidemic in recent years, which continues to progress steadily, currently affecting more than 2 billion people worldwide. Due to its heterogeneity, obesity has a negative impact on the work of almost all organs and systems of the body, contributing to the emergence of new concomitant diseases and pathological conditions that significantly worsen the quality of life of these patients. Thus, a close relationship between type 2 diabetes mellitus and cognitive impairment has long been known, as well as with a number of other somatic diseases: coronary heart disease, atherosclerosis, non-alcoholic fatty liver disease, dyslipidemia, malignant neoplasms and other associated pathological conditions against the background of overweight and obesity.

Currently, the problem of the relationship of cognitive impairment in patients with overweight or changes in the glycemic profile is very relevant, due to the high prevalence and insufficient study of this issue.

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The authors declare that there are no conflicts of interest present.