problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl13465problendo-13465Research ArticleКлинические рекомендацииClinical guidelinesРезолюция национального междисциплинарного совета экспертов «Высокодозный витамин D (Девилам) в практике акушера-гинеколога»Resolution of the national interdisciplinary council of experts "High-dose vitamin D (Devilam) in the practice of an obstetrician-gynecologist"https://orcid.org/0000-0001-8425-0020АндрееваЕ. Н.AndreevaE. N.

Андреева Елена Николаевна, д.м.н., профессор

Москва

Elena N. Andreeva, MD, PhD, Professor

Moscow

endogin@mail.ruhttps://orcid.org/0000-0001-7014-6492АртымукН. В.ArtymukN. V.

Артымук Наталья Владимировна, д.м.н., профессор

Researcher ID: N-2919-2016

Scopus Author ID: 35108913300

Кемерово

 

Natalya V. Artymuk, MD, PhD, Professor

Researcher ID: N-2919-2016

Scopus Author ID: 35108913300

Kemerovo

artymuk@gmail.comВеснинаА. Ф.VesninaA. F.

Веснина Анна Федоровна, к.м.н.

Москва

Anna F. Vesnina, MD, PhD

Moscow

annvesnina@yandex.ruhttps://orcid.org/0000-0003-4431-3917ЗазерскаяИ. Е.ZazerskayaI. E.

Зазерская Ирина Евгеньевна, д.м.н., профессор

Санкт-Петербург

Scopus Author ID: 55981393900

Irina E. Zazerskaya, MD, PhD, Professor

St. Petersburg

zazera@mail.ruhttps://orcid.org/0000-0003-1040-6736КарахалисЛ. Ю.KarakhalisL. Y.

Карахалис Людмила Юрьевна, д.м.н., профессор

Краснодар

Scopus Author ID: 56611990800

Lyudmila Y. Karakhalis, MD, PhD, Professor

Krasnodar

Scopus Author ID: 56611990800

lomela@mail.ruКатковаН. Ю.KatkovaN. Y.

Каткова Надежда Юрьевна, д.м.н., профессор

Нижний Новгород

Scopus Author ID: 57200605131

Nadezhda Y. Katkova, MD, PhD, Professor

 Nizhny Novgorod

Scopus Author ID: 57200605131

katkova_nu@inbox.ruhttps://orcid.org/0000-0001-6539-466XПигароваЕ. А.PigarovaE. A.

Пигарова Екатерина Александровна, д.м.н.

Москва

Ekaterina A. Pigarova, MD, PhD

Moscow

kpigarova@gmail.comhttps://orcid.org/0000-0002-2908-8275СахаутдиноваИ. В.SakhautdinovaI. V.

Сахаутдинова Индира Венеровна, д.м.н., профессор

Уфа

Scopus Author ID: 57210148389

Indira V. Sakhautdinova, MD, PhD, Professor

Ufa

Scopus Author ID: 57210148389

indira2172@yandex.ruhttps://orcid.org/0000-0003-3390-8034СпиридоноваН. В.SpiridonovaN. V.

Спиридонова Наталья Владимировна, д. м. н., профессор

Самара

Researcher ID: S-6918-2016

Scopus Author ID: 56089251400

Natalya V. Spiridonova, MD, PhD, Professor

Samara

Researcher ID: S-6918-2016

Scopus Author ID: 56089251400

nvspiridonova@mail.ruhttps://orcid.org/0000-0001-5309-0087ТапильскаяН. И.TapilskayaN. I.

Тапильская Наталья Игоревна, д.м.н., профессор

Санкт-Петербург

Natalya I. Tapilskaya, MD, PhD, Professor

St. Petersburg

tapnatalia@yandex.ruhttps://orcid.org/0000-0003-1940-4534ХамошинаМ. Б.KhamoshinaM. B.

Хамошина Марина Борисовна, д.м.н., профессор

Москва

Researcher ID: E-6154-2017

Scopus Author ID: 36182882600

Marina B. Khamoshina, MD, PhD, Professor

Moscow

mbax999@mail.ruhttps://orcid.org/0000-0001-7177-0254ШереметьеваЕ. В.SheremetyevaE. V.

Шереметьева Екатерина Викторовна, к.м.н.

117036, Москва, ул. Дмитрия Ульянова, д. 11

Ekaterina V. Sheremetyeva, MD, PhD

11 Dm. Ulyanov str., Moscow, 117036

s1981k@yandex.ruhttps://orcid.org/0000-0003-2864-066XЮреневаС. В.YurenevaS. V.

Юренева Светлана Владимировна, д.м.н., профессор

Москва

Svetlana V. Yureneva, MD, PhD, Professor

Moscow

syureneva@gmail.comhttps://orcid.org/0000-0002-6551-4147ЯрмолинскаяМ. И.YarmolinskayaM. I.

Ярмолинская Мария Игоревна, д.м.н., профессор

Санкт-Петербург

Maria I. Yarmolinskaya, MD, PhD, Professor

 St. Petersburg

m.yarmolinskaya@gmail.comНациональный медицинский исследовательский центр эндокринологии; Российский университет медициныРоссияEndocrinology Research Centre; Moscow State University of Medicine and DentistryRussian FederationКемеровский государственный медицинский университетРоссияKemerovo State Medical UniversityRussian FederationНациональный медицинский исследовательский центр эндокринологииРоссияEndocrinology Research CentreRussian FederationНациональный медицинский исследовательский центр им. В. А. АлмазоваРоссияNational Medical Research Center named after. V. A. AlmazovaRussian FederationКубанский государственный медицинский университетРоссияKuban State Medical UniversityRussian FederationПриволжский исследовательский медицинский университетРоссияPrivolzhsky Research Medical UniversityRussian FederationБашкирский государственный медицинский университетРоссияBashkir State Medical UniversityRussian FederationСамарский государственный медицинский университетРоссияSamara State Medical UniversityRussian FederationНаучно-исследовательский институт акушерства, гинекологии и репродуктологии имени Д.О. ОттаРоссияResearch Institute of Obstetrics, Gynecology and Reproductology named after D.O. OttaRussian FederationРоссийский университет дружбы народовРоссияPeoples’ Friendship University of RussiaRussian FederationНациональный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени В.И. КулаковаРоссияNational Medical Research Center for Obstetrics, Gynecology and Perinatology named after V.I. KulakovaRussian Federation202409052024702103116Copyright © Андреева Е.Н., Артымук Н.В., Веснина А.Ф., Зазерская И.Е., Карахалис Л.Ю., Каткова Н.Ю., Пигарова Е.А., Сахаутдинова И.В., Спиридонова Н.В., Тапильская Н.И., Хамошина М.Б., Шереметьева Е.В., Юренева С.В., Ярмолинская М.И., 20242024Андреева Е.Н., Артымук Н.В., Веснина А.Ф., Зазерская И.Е., Карахалис Л.Ю., Каткова Н.Ю., Пигарова Е.А., Сахаутдинова И.В., Спиридонова Н.В., Тапильская Н.И., Хамошина М.Б., Шереметьева Е.В., Юренева С.В., Ярмолинская М.И.Andreeva E.N., Artymuk N.V., Vesnina A.F., Zazerskaya I.E., Karakhalis L.Y., Katkova N.Y., Pigarova E.A., Sakhautdinova I.V., Spiridonova N.V., Tapilskaya N.I., Khamoshina M.B., Sheremetyeva E.V., Yureneva S.V., Yarmolinskaya M.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/13465

28 марта 2024 года в Москве состоялся Совет Экспертов «Высокодозовый витамин D (Девилам) в практике акушерагинеколога, гинеколога и эндокринолога» с участием ведущих экспертов гинекологов, эндокринологов и акушеровгинекологов, в рамках которого были обсуждены новые возможности применения высокодозного витамина D у пациенток различных возрастов, нуждающихся в коррекции имеющихся дефицита или недостаточности витамина D.

On March 28, 2024, the Council of Experts “High-dose vitamin D (Devilam) in the practice of obstetrician-gynecologist, gynecologist and endocrinologist” was held in Moscow with the participation of leading experts gynecologists, endocrinologists and obstetricians-gynecologists, during which new possibilities for the use of high-dose vitamin D in patients of various ages who need correction of existing vitamin D deficiency or insufficiency.

25-ОН-Dвитамин Dгинекологияакушерство25-OH-Dvitamin DgynecologyobstetricsProekt klinicheskikh rekomendatsii RAE. Defitsit vitamina D. NMITs Endokrinologii MZ RF, 2021Pludowski Pawel Takacs Istvan Boyanov Mihail Belaya Zhanna Diaconu Camelia C. Mokhort Tatiana Zherdova Nadiia Rasa Ingvars Payer Juraj Pilz Stefan Clinical Practice in the Prevention, Diagnosis and Treatment of Vitamin D Deficiency: A Central and Eastern European Expert Consensus Statement Nutrients 2022 04 1483 14 7 10.3390/nu14071483Pigarova Ekaterina A. Petrushkina Alexandra A. Non-classical effects of vitamin D Osteoporosis and Bone Diseases 2018 04 90 101 20 3 10.14341/osteo2017390-101Ignat'eva M.A., Novikova S.V., Kostinov M.P. Metabolizm vitamina D pri normal'nykh i patologicheskikh sostoyaniyakh u beremennykh // Rossiiskii vestnik akushera-ginekologa. — 2018. — T. 18. — №1. — S. 30-36Kumar Jogender Yadav Arushi Vitamin D deficiency pandemic among pregnant women Journal of Family Medicine and Primary Care 2019 04 1515 8 4 10.4103/jfmpc.jfmpc_202_19Suplotova Lyudmila A. Avdeeva Valeria A. Pigarova Ekaterina A. Rozhinskaya Liudmila Ya. Karonova Tatiana L. Troshina Ekaterina A. The first Russian multicenter non-interventional registry study to study the incidence of vitamin D deficiency and insufficiency in Russian Federation Terapevticheskii arkhiv 2021 11 1209 1216 93 10 10.26442/00403660.2021.10.201071Manson JoAnn E. Brannon Patsy M. Rosen Clifford J. Taylor Christine L. Vitamin D Deficiency — Is There Really a Pandemic? New England Journal of Medicine 2016 11 1817 1820 375 19 10.1056/nejmp1608005Holick Michael F. The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention Reviews in Endocrine and Metabolic Disorders 2017 05 153 165 18 2 10.1007/s11154-017-9424-1da Silveira Erika Aparecida Moura Letícia de Almeida Nogueira e Castro Maria Clara Rezende Kac Gilberto Hadler Maria Claret Costa Monteiro Noll Priscilla Rayanne E. Silva Noll Matias Rezende Andréa Toledo de Oliveira Delpino Felipe Mendes Oliveira Cesar de Prevalence of Vitamin D and Calcium Deficiency and Insufficiency in Women of Childbearing Age and Associated Risk Factors: A Systematic Review and Meta-Analysis Nutrients 2022 10 4351 14 20 10.3390/nu14204351Durá-Travé Teodoro Gallinas-Victoriano Fidel Pregnancy, Breastfeeding, and Vitamin D International Journal of Molecular Sciences 2023 07 11881 24 15 10.3390/ijms241511881Muscogiuri Giovanna Altieri Barbara de Angelis Cristina Palomba Stefano Pivonello Rosario Colao Annamaria Orio Francesco Shedding new light on female fertility: The role of vitamin D Reviews in Endocrine and Metabolic Disorders 2017 01 273 283 18 3 10.1007/s11154-017-9407-2Várbíró Szabolcs Takács István Tűű László Nas Katalin Sziva Réka Eszter Hetthéssy Judit Réka Török Marianna Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review Nutrients 2022 04 1649 14 8 10.3390/nu14081649Khabarov S.V., Khadartseva K.A., Volkov V.G. Vitamin D i reproduktivnoe zdorov'e zhenshchiny // Rossiiskii vestnik akushera-ginekologa. — 2020. — T. 20. — №5. — S. 45-53Mansur José Luis Oliveri Beatriz Giacoia Evangelina Fusaro David Costanzo Pablo René Vitamin D: Before, during and after Pregnancy: Effect on Neonates and Children Nutrients 2022 05 1900 14 9 10.3390/nu14091900Adamczewska Daria Słowikowska-Hilczer Jolanta Walczak-Jędrzejowska Renata The Association between Vitamin D and the Components of Male Fertility: A Systematic Review Biomedicines 2022 12 90 11 1 10.3390/biomedicines11010090Calagna Gloria Catinella Valeria Polito Salvatore Schiattarella Antonio De Franciscis Pasquale D’Antonio Francesco Calì Giuseppe Perino Antonino Cucinella Gaspare Vitamin D and Male Reproduction: Updated Evidence Based on Literature Review Nutrients 2022 08 3278 14 16 10.3390/nu14163278Homayouni-Meymandi M, Sotoodehnejadnematalahi F, Nasr-Esfahani MH. Relationship between Serum Vitamin D in Male, Sperm Function and Clinical Outcomes in Infertile Men Candidate for ICSI: A Cohort Study. Int J Fertil Steril. 2022;16(2):115-121. doi: https://doi.org/10.22074/IJFS.2021.522049.1067Morshed-Behbahani Bahar Doryanizadeh Leila Shahali Shadab Shahabi Saeed Montazeri Ali Effect of and the association between vitamin D and outcomes of assisted reproductive techniques among infertile men and women: protocol for an overview of systematic reviews and meta-analysis BMJ Open 2023 03 e060483 13 3 10.1136/bmjopen-2021-060483Cappola A, Auchtus R, Fuleihan G, et al. Hormones and Aging: An Endocrine Society Scientific Statement. The Journal of Clinical Endocrinology & Metabolism. 2023;00: 1–40. doi: https://doi.org/10.1210/clinem/dgad225Brøndum-Jacobsen P, Benn M, Jensen GB, Nordestgaard BG. 25-hydroxyvitamin D levels and risk of ischemic heart disease, myocardial infarction, and early death: population-based study and meta-analyses of 18 and 17 studies. Arterioscler Thromb Vasc Biol. 2012;32(11):2794-2802Ju SY, et al. Low 25-hydroxyvitamin D levels and the risk of frailty syndrome: a systematic review and dose-response meta-analysis. BMC Geriatr. 2018;18(1):206Zhang Yu Fang Fang Tang Jingjing Jia Lu Feng Yuning Xu Ping Faramand Andrew Association between vitamin D supplementation and mortality: systematic review and meta-analysis BMJ 2019 08 l4673 10.1136/bmj.l4673Gaksch M, et al. Vitamin D and mortality: individual participant data meta-analysis of standardized 25–hydroxyvitamin D in 26916 individuals from a European consortium. PLoS One. 2017;12(2):e0170791Chakhtoura Marlene Bacha Dania S Gharios Charbel Ajjour Sara Assaad Mariam Jabbour Yara Kahale Francesca Bassatne Aya Antoun Stephanie Akl Elie A Bouillon Roger Lips Paul Ebeling Peter R El-Hajj Fuleihan Ghada Vitamin D Supplementation and Fractures in Adults: A Systematic Umbrella Review of Meta-Analyses of Controlled Trials The Journal of Clinical Endocrinology & Metabolism 2021 10 882 898 107 3 10.1210/clinem/dgab742LeBoff MS, et al. Supplemental vitamin D and incident fractures in midlife and older adults. N Engl J Med. 2022;387(4):299-309Gillespie LD, Robertson MC, Gillespie WJ, et al. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev. 2012;2021(6). doi: https://doi.org/10.1002/14651858.CD007146.pub3Baranov I.I., Dorofeinikov V.V., Zazerskaya I.E., i dr. Mezhdistsiplinarnoe rukovodstvo po profilaktike i lecheniyu defitsita vitamina D v pregravidarnom periode, vo vremya beremennosti i posle rodov (kod po Mezhdunarodnoi klassifikatsii boleznei 10-go peresmotra — E55) / Pod red. Grinevoi E.N., Kogan I.Yu., Uvarovoi E.V. Sankt-Peterburg: Eko-Vektor, 2020. 79 s.Mousa A, Abell S, Scragg R, Courten B. Vitamin D in reproductive health and pregnancy. Semin Reprod Med. 2016;34:e1–13Platonova N. M. Rybakova A. A. Nikankina L. V. Malysheva N. M. Andreeva E. N. Pokusaeva V. N. Boyko E. L. Troshina E. A. Vitamin D and pregnancy: current state of the problem in the central regions of the Russian Federation Problems of Endocrinology 2021 01 81 87 66 6 10.14341/probl12693Gregor S, Casorat M, Amuchastegu S, et al. Regulatory T cells induced by 1 alpha, 25-dihydroxy vitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol. 2001;167:1945–1953Tehrani HG, Mostajeran F, Banihashemi B. Effect of vitamin D supplementation on the incidence of gestational diabetes. Adv Biomed Res. 2017;6:79Moon RJ, Harvey NC, Cooper C. Endocrinology in pregnancy: Influence of maternal vitamin D status on obstetric outcomes and the fetal skeleton. Eur J Endocrinol. 2015;173:69–83Instruktsiya po meditsinskomu primeneniyu lekarstvennogo preparata Devilam. https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=1d0d5e5a-37a5-4fa8-8261-888e9194cd06Laganà AS, Vitale SG, BanFrangež H, et al. Vitamin D in human reproduction: the more, the better? An evidence-based critical appraisal. Eur Rev Med Pharmacol Sci. 2017;21:4243–4251Monastra G, De Grazia S, De Luca L, Vittorio S, Unfer V. Vitamin D: a steroid hormone with progesterone-like activity. Eur Rev Med Pharmacol Sci. 2018;22(8):2502-2512Ozkan S, Jinda S, Greenseid K, et al. Replete vitamin D stores predictre productive success following IVF. Fertil Steril. 2010;94(4):1314–1319Garbedian K, Boggild M, Moody J, Liu KE. Effect of vitamin D status on clinical pregnancy rates following in vitro fertilization. CMA J Open. 2013;1(2):77–82Paffoni A, Ferrari S, Vigano P, et al. Vitamin D deficiency and infertility: insights from in vitro fertilization cycles. J Clin Endocrinol Metab. 2014;99:2372–2376Polyzos NP, Anckaert E, Guzman L, et al. Vitamin D deficiency and pregnancy rates in women undergoing single embryo, blastocyst stage, transfer (SET) for IVF/ICSI. Hum Reprod. 2014;29:2032–2040Zhao J, Huang X, Xu B, et al. Whether vitamin D was associated with clinical outcome after IVF/ICSI: a systematic review and metaanalysis. Reprod Biol Endocrinol. 2018;16:13Chu J, Gallos I, Tobias A, et al. Vitamin D and assisted reproductive treatment outcome: A systematic review and meta-analysis. Hum Reprod. 2018;33(1):65–80Klinicheskie rekomendatsii. Defitsit vitamina D u vzroslykh: diagnostika, lechenie i profilaktika / Rossiiskaya assotsiatsiya endokrinologov, FGBU «Endokrinologicheskii nauchnyi tsentr» Minzdrava Rossii. M., 2015. 75 s.Profilaktika, diagnostika i lechenie defitsita vitamina D i kal'tsiya dlya vzroslogo naseleniya i u patsientov s osteoporozom. Rekomendatsii RAOP, 2016Grodnitskaya E.E., Kurtser M.A. Defitsit vitamina D u zhenshchin s sindromom polikistoznykh yaichnikov // Problemy reproduktsii. 2015;21(5):38-42Alimirah F, Peng X, Yuan L. Cross talk between the peroxisome proliferator-activated receptorγ (PPAR γ) and the vitamin D receptor (VDR) in human breast cancer cells: PPARγ binds to VDR and inhibits 1α,25-dihydroxy vitamin D3 mediated transactivation. Exp Cell Res. 2012;318(19):2490–2497Pal L, Berry A, Coraluzzi L, et al. Therapeutic effects of vitamin D and calciumin in overweight women with overweight with polycystic ovary syndrome. Gynecol Endocrinol. 2012;28(12):965–968He C, Lin Z, Robb SW, Ezeamama AE. Serum vitamin D levels and polycystic ovary syndrom: A systematic review and metaanalysis. Nutrients. 2015;7:4555–4577Kumar A, Barki S, Raghav V, et al. Correlation of vitamin D with metabolic parameters in polycystic ovarian syndrome. Journal of Family Medicine and Primary Care. 2017;6(1):115Shojaeian Z, Sadeghi R, Latifnejad Roudsari R. Calcium and vitamin D supplementation effects on metabolic factors, menstrual cycles and follicular responses in women with polycystic ocvary syndrome: A systematic review and meta-analysis. Caspian J Intern Med. 2019;10(4):359-369Pal L, Zhang H, Williams J, et al. Vitamin D status relates to reproductive outcome in women with polycystic ovary syndrome: secondary analysis of a multicenter randomized controlled trial. J Clin Endocrinol Metab. 2016;101:3027–3035Zhao J, Liu S, Wang Y, et al. Vitamin D improves the outcome of in vitro fertilization (IVF) in infertile women with polycystic ovary syndrome and insulin resistance. Minerva Med. 2019;110(3):199–208BARNETT REBECCA BANKS NICOLE DECHERNEY ALAN H. Endometriosis and Fertility Preservation Clinical Obstetrics & Gynecology 2017 07 517 523 60 3 10.1097/grf.0000000000000311Parasar Parveen Ozcan Pinar Terry Kathryn L. Endometriosis: Epidemiology, Diagnosis and Clinical Management Current Obstetrics and Gynecology Reports 2017 01 34 41 6 1 10.1007/s13669-017-0187-1Aerts Leen Grangier Lorraine Streuli Isabelle Dällenbach Patrick Marci Roberto Wenger Jean-Marie Pluchino Nicola Psychosocial impact of endometriosis: From co-morbidity to intervention Best Practice & Research Clinical Obstetrics & Gynaecology 2018 02 2 10 50 10.1016/j.bpobgyn.2018.01.008Yarmolinskaya M.I., Ailamazyan E.K. Genital'nyi endometrioz: Razlichnye grani problemy. — Spb.: EkoVektor, 2017. — 615 s.Giampaolino Pierluigi Corte Luigi D. Foreste Virginia Bifulco Giuseppe Is there a Relationship Between Vitamin D and Endometriosis? An Overview of the Literature Current Pharmaceutical Design 2019 07 2421 2427 25 22 10.2174/1381612825666190722095401Miyashita Mariko Koga Kaori Izumi Gentaro Sue Fusako Makabe Tomoko Taguchi Ayumi Nagai Miwako Urata Yoko Takamura Masashi Harada Miyuki Hirata Tetsuya Hirota Yasushi Wada-Hiraike Osamu Fujii Tomoyuki Osuga Yutaka Effects of 1,25-Dihydroxy Vitamin D3 on Endometriosis The Journal of Clinical Endocrinology & Metabolism 2016 04 2371 2379 101 6 10.1210/jc.2016-1515Somigliana Edgardo Panina-Bordignon Paola Murone Simone Di Lucia Pietro Vercellini Paolo Vigano Paola Vitamin D reserve is higher in women with endometriosis Human Reproduction 2007 06 2273 2278 22 8 10.1093/humrep/dem142Gil Ángel Plaza-Diaz Julio Mesa María Dolores Vitamin D: Classic and Novel Actions Annals of Nutrition and Metabolism 2018 01 87 95 72 2 10.1159/000486536Pagliardini Luca Vigano’ Paola Molgora Michela Persico Paola Salonia Andrea Vailati Simona Paffoni Alessio Somigliana Edgardo Papaleo Enrico Candiani Massimo High Prevalence of Vitamin D Deficiency in Infertile Women Referring for Assisted Reproduction Nutrients 2015 12 9972 9984 7 12 10.3390/nu7125516Bodnar Lisa M. Simhan Hyagriv N. Powers Robert W. Frank Michael P. Cooperstein Emily Roberts James M. High Prevalence of Vitamin D Insufficiency in Black and White Pregnant Women Residing in the Northern United States and Their Neonates The Journal of Nutrition 2018 01 447 452 137 2 10.1093/jn/137.2.447Tandoi Iacopo Somigliana Edgardo Riparini Jennifer Ronzoni Stefania Vigano’ Paola Candiani Massimo High Rate of Endometriosis Recurrence in Young Women Journal of Pediatric and Adolescent Gynecology 2011 09 376 379 24 6 10.1016/j.jpag.2011.06.012Cho Min-Chul Kim Jin Hyun Jung Myeong Hee Cho In Ae Jo Hyen Chul Shin Jeong Kyu Lee Soon Ae Choi Won Jun Lee Jong Hak Analysis of vitamin D-binding protein (VDBP) gene polymorphisms in Korean women with and without endometriosis Clinical and Experimental Reproductive Medicine 2019 08 132 139 46 3 10.5653/cerm.2019.00122Harris H. R. Chavarro J. E. Malspeis S. Willett W. C. Missmer S. A. Dairy-Food, Calcium, Magnesium, and Vitamin D Intake and Endometriosis: A Prospective Cohort Study American Journal of Epidemiology 2013 02 420 430 177 5 10.1093/aje/kws247Baek Jong Chul Jo Jae Yoon Lee Seon Mi Cho In Ae Shin Jeong Kyu Lee Soon Ae Lee Jong Hak Cho Min-Chul Choi Won Jun Differences in 25-hydroxy vitamin D and vitamin D-binding protein concentrations according to the severity of endometriosis Clinical and Experimental Reproductive Medicine 2019 08 125 131 46 3 10.5653/cerm.2018.00416Anastasi Emanuela Fuggetta Eliana De Vito Corrado Migliara Giuseppe Viggiani Valentina Manganaro Lucia Granato Teresa Benedetti Panici Pierluigi Angeloni Antonio Porpora Maria Grazia Low levels of 25-OH vitamin D in women with endometriosis and associated pelvic pain Clinical Chemistry and Laboratory Medicine (CCLM) 2017 04 55 12 10.1515/cclm-2017-0016Denisova Alexandra S. Yarmolinskaya Maria I. Tkachenko Natalia N. Assessment of 25(OH)D status in patients with genital endometriosis and clinical efficacy of cholecalciferol in the treatment of the disease Journal of obstetrics and women's diseases 2021 10 125 133 70 4 10.17816/jowd62883Ciavattini Andrea Serri Matteo Delli Carpini Giovanni Morini Stefano Clemente Nicolò Ovarian endometriosis and vitamin D serum levels Gynecological Endocrinology 2016 11 164 167 33 2 10.1080/09513590.2016.1239254Orazov M.R., Radzinskii V.E., Khamoshina M.B. i dr. Vitamin D3 (kholekal'tsiferol) i tazovaya bol', indutsirovannaya endometriozom yaichnikov // Trudnyi patsient. — 2018. — T.16. — №4. — S. 34-39Yarmolinskaya Maria Denisova Alexandra Tkachenko Natalia Ivashenko Tatyna Bespalova Olesya Tolibova Gulrukhsor Tral Tatyana Vitamin D significance in pathogenesis of endometriosis Gynecological Endocrinology 2021 12 40 43 37 sup1 10.1080/09513590.2021.2006516Zelenko Z. Aghajanova L. Irwin J. C. Giudice Linda C. Nuclear Receptor, Coregulator Signaling, and Chromatin Remodeling Pathways Suggest Involvement of the Epigenome in the Steroid Hormone Response of Endometrium and Abnormalities in Endometriosis Reproductive Sciences 2011 12 152 162 19 2 10.1177/1933719111415546Bergadà Laura Pallares Judit Arcidiacono Maria Vittoria Cardus Anna Santacana Maria Valls Joan Cao Gonzalo Fernàndez Elvira Dolcet Xavier Dusso Adriana S Matias-Guiu Xavier Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma Laboratory Investigation 2014 04 608 622 94 6 10.1038/labinvest.2014.57Yarmolinskaya M.I., i dr. Analiz ekspressii retseptorov vitamina D u bol'nykh naruzhnym genital'nym endometriozom // Akusherstvo i ginekologiya. — 2021. — №3. — S. 117-123Mariani M. Vigano P. Gentilini D. Camisa B. Caporizzo E. Di Lucia P. Monno A. Candiani M. Somigliana E. Panina-Bordignon P. The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation Human Reproduction 2012 05 2010 2019 27 7 10.1093/humrep/des150Abbas Manal A. Taha Mutasem O. Disi Ahmad M. Shomaf Maha Regression of endometrial implants treated with vitamin D3 in a rat model of endometriosis European Journal of Pharmacology 2013 06 72 75 715 1-3 10.1016/j.ejphar.2013.06.016Yildirim Basak Guler Tolga Akbulut Metin Oztekin Ozer Sariiz Gulcin 1–Alpha, 25–Dihydroxyvitamin D3 Regresses Endometriotic Implants in Rats by Inhibiting Neovascularization and Altering Regulation of Matrix Metalloproteinase Postgraduate Medicine 2014 01 104 110 126 1 10.3810/pgm.2014.01.2730Yarmolinskaya M.I., Denisova A.S., Andreeva N.Yu. Effektivnost' primeneniya vitamina D3 (kolekal'tsiferola) v terapii khirurgicheski indutsirovannogo endometrioza u krys // Rossiiskii vestnik akushera-ginekologa. — 2019. — T. 19. — №3. — S. 37-42Burjiah Alfi adi Ashon Widjiati Widjiati Vitamin D inhibited endometriosis development in mice model through interleukin 17 modulation Open Veterinary Journal 2022 12 956 12 6 10.5455/ovj.2022.v12.i6.23Almassinokiani Fariba Khodaverdi Sepideh Solaymani-dodaran Masoud Akbari Peyman Pazouki Abdolreza Effects of Vitamin D on Endometriosis-Related Pain: A Double-Blind Clinical Trial Medical Science Monitor 2016 12 4960 4966 22 10.12659/msm.901838Lasco Antonino Improvement of Primary Dysmenorrhea Caused by a Single Oral Dose of Vitamin D: Results of a Randomized, Double-blind, Placebo-Controlled Study Archives of Internal Medicine 2012 02 366 172 4 10.1001/archinternmed.2011.715Stratton P, Berkley KJ. Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications. Hum Reprod Update. 2011;17:327-346. doi: https://doi.org/10.1093/humupd/dmq050Yarmolinskaya M.I., Denisova A.S. Sposob lecheniya naruzhnogo genital'nogo endometrioza, 2020Yarmolinskaya M.I. red. Medikamentoznaya terapiya genital'nogo endometrioza: realii i perspektivy. Rukovodstvo dlya vrachei. M.: GEOTAR-Media; 2021. 384 s.Sha Sha Chen Li-Ju Brenner Hermann Schöttker Ben Associations of 25-hydroxyvitamin D status and vitamin D supplementation use with mortality due to 18 frequent cancer types in the UK Biobank cohort European Journal of Cancer 2023 07 113241 191 10.1016/j.ejca.2023.113241de Sousa Almeida-Filho Benedito De Luca Vespoli Heloisa Pessoa Eduardo Carvalho Machado Murilo Nahas-Neto Jorge Nahas Eliana Aguiar Petri Vitamin D deficiency is associated with poor breast cancer prognostic features in postmenopausal women The Journal of Steroid Biochemistry and Molecular Biology 2017 10 284 289 174 10.1016/j.jsbmb.2017.10.009Norman P.E. Powell J.T. Vitamin D and Cardiovascular Disease Circulation Research 2014 01 379 393 114 2 10.1161/circresaha.113.301241Zhang Yu Fang Fang Tang Jingjing Jia Lu Feng Yuning Xu Ping Faramand Andrew Association between vitamin D supplementation and mortality: systematic review and meta-analysis BMJ 2019 08 l4673 10.1136/bmj.l4673Palma F. Volpe A. Villa P. Cagnacci A. Vaginal atrophy of women in postmenopause. Results from a multicentric observational study: The AGATA study Maturitas 2015 09 40 44 83 10.1016/j.maturitas.2015.09.001Anagnostis P, et al. EMAS position statement: Vitamin D and menopausal health. Maturitas. 2023;169:2–9. doi: https://doi.org/10.1016/j.maturitas.2022.12.0062Bener Abdulbari Saleh NajahM Low vitamin D, and bone mineral density with depressive symptoms burden in menopausal and postmenopausal women Journal of Mid-life Health 2015 09 108 6 3 10.4103/0976-7800.165590Berridge Michael J. Vitamin D and Depression: Cellular and Regulatory Mechanisms Pharmacological Reviews 2017 02 80 92 69 2 10.1124/pr.116.013227Morozova Yulia E. Tarasova Marina A. The physiological role of vitamin D and the significance of its deficiency in the pathogenesis of climacteric syndrome Journal of obstetrics and women's diseases 2018 07 74 82 67 3 10.17816/jowd67374-82Riazi Hedyeh Ghazanfarpour Masumeh Taebi Mahboubeh Abdolahian Somayeh Effect of Vitamin D on the Vaginal Health of Menopausal Women: A Systematic Review Journal of Menopausal Medicine 2020 01 109 25 3 10.6118/jmm.19194Purdue-Smithe Alexandra C Whitcomb Brian W Szegda Kathleen L Boutot Maegan E Manson JoAnn E Hankinson Susan E Rosner Bernard A Troy Lisa M Michels Karin B Bertone-Johnson Elizabeth R Vitamin D and calcium intake and risk of early menopause , The American Journal of Clinical Nutrition 2017 05 1493 1501 105 6 10.3945/ajcn.116.145607Alinia Tahereh Sabour Siamak Hashemipour Mahin Hovsepian Silva Pour Homeyra Rais Jahanfar Shayesteh Relationship between vitamin D levels and age of menopause and reproductive lifespan: Analysis based on the National health and nutrition examination survey (NHANES) 2001–2018 European Journal of Obstetrics & Gynecology and Reproductive Biology 2023 09 183 189 289 10.1016/j.ejogrb.2023.09.003Speroff L, Fritz MA. 8th ed. Philadelphia: Lippincott Williams and Wilkins. Clinical gynaecologic endocrinology and infertility. 2011:566–88Martins D, Wolf M, Pan D, et al. Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: Data from the Third National Health and Nutrition Examination Survey. Arch Intern Med. 2007;167:1159–65Vacek JL, Vanga SR, Good M, et al. Vitamin D deficiency and supplementation and relation to cardiovascular health. Am J Cardiol. 2012;109:359–63Mei Zhaojun Hu Hong Zou Yi Li Dandan The role of vitamin D in menopausal women’s health Frontiers in Physiology 2023 06 14 10.3389/fphys.2023.1211896Erdélyi Aliz Pálfi Erzsébet Tűű László Nas Katalin Szűcs Zsuzsanna Török Marianna Jakab Attila Várbíró Szabolcs The Importance of Nutrition in Menopause and Perimenopause—A Review Nutrients 2023 12 27 16 1 10.3390/nu16010027Stefanska A, Bergmann K, Sypniewska G. Metabolic Syndrome and Menopause: Pathophysiology, Clinical and Diagnostic Significance. Adv Clin Chem. 2015;72:1-75Janssen I, Powell LH, Crawford S, Lasley B, Sutton-Tyrrell K. Menopause and the metabolic syndrome: the Study of Women’s Health Across the Nation. Arch Intern Med. 2008;168:1568-75Ferreira P. P. Cangussu L. Bueloni-Dias F. N. Orsatti C. L. Schmitt E. B. Nahas-Neto J. Nahas E. A. P. Vitamin D supplementation improves the metabolic syndrome risk profile in postmenopausal women Climacteric 2019 05 24 31 23 1 10.1080/13697137.2019.1611761Hao L, Lu A, Gao H, Niu J, Prabahar K, Seraj SS, Pan Y. The Effects of Vitamin D on Markers of Glucose and Obesity in Postmenopausal Women: A Meta-analysis of Randomized Controlled Trials. Clin Ther. 2023;45(9):913-920. doi: https://doi.org/10.1016/j.clinthera.2023.07.009.1Legan Mateja Barbič Matija Osredkar Joško Blaganje Mija Association of vitamin D deficiency and pelvic organ prolapse in postmenopausal women: a cross-sectional study Women's Midlife Health 2022 08 8 1 10.1186/s40695-022-00078-7Paul ZR, Khanam NN, Barai SC, et al. Association of Low Vitamin D Level with Pelvic Organ Prolapse in Post Menopausal Women: A Case Control Study. Mymensingh Med J. 2023;32(4):1109-1117Bala Ripan Kaur Harmanpreet Nagpal Madhu Role of vitamin D in urogenital health of geriatric participants Journal of Mid-life Health 2017 03 28 8 1 10.4103/jmh.jmh_84_16Sidorova I.S., Unanyan A.L., Ageev M.B., i dr. Sovremennoe sostoyanie voprosa o patogeneze, klinike, diagnostike i lechenii miomy matki u zhenshchin reproduktivnogo vozrasta // Akusherstvo. Ginekologiya. Reproduktsiya. — 2012. — T. 6. — №4. — S. 25Adamyan L.V., Serov V.N., Sukhikh G.T., Filippov O.S. Klinicheskie rekomendatsii // Akusherstvo i ginekologiya (spetsvypusk). Problemy reproduktsii. — 2015. — T. 21. — №6. — S. 321AAGL Practice Report: Practice Guidelines for the Diagnosis and Management of Submucous Leiomyomas. 2012;19:152–171SOGC clinical practice guideline, The Management of Uterine Leiomyomas. 2015;318Bjelakovic G, Gluud L, Nikolova D, et al. Vitamin D supplementation for prevention of cancer in adultsKim T.Kh., Li Kh.Kh., Park Dzh. Immunogistokhimicheskoe obnaruzhenie retseptora 1,25-digidroksi vitamina D vo vlagalishche cheloveka. Iran Dzh. // Reprod Med. 2014. — T. 12. — S. 805–810;Paik Dzh.V., Meier M.B. Retseptor vitamina D: novye paradigmy regulyatsii ekspressii genov s pomoshch'yu 1,25-digidroksivitamina D(3) //Endocrinol Metab Clin North Am. 2010. — T. 39. — S. 255–269Iyldirim B., Kaleli B., Duzkan E., Topuz O. Vliyanie lecheniya vitaminom D v postmenopauze na atrofiyu vlagalishcha // Maturitas. — 2004. — T. 49. — S. 334–337Bala R., Kaur Kh., Nagpal M. Podlinnost' vitamina D v modifitsirovannom indekse zdorov'ya vlagalishcha u pozhilykh lyudei. Int J Reprod Contracept Obstet Gynecol. — 2016. — T. 5. — S. 4119–4122Rad P., Tadaion M., Abbaspur M., i dr. Vliyanie vitamina D na atrofiyu vlagalishcha u zhenshchin v postmenopauze. Iran. // J Nurs Midwifery Res. — 2015. — T. 20. — S. 211–215Cheka M.A., Garrido A., Prat M., i dr. Sravnenie raloksifena i kal'tsiya plyus vitamina D pri vaginal'noi atrofii posle prekrashcheniya dlitel'noi gormonal'noi terapii v postmenopauze u zhenshchin s osteoporozom. Randomizirovannoe odnoletnee prospektivnoe issledovanie s zamaskirovannoi otsenkoi // Maturitas. — 2005. — T. 52. — S. 70–77Zareai M. Vliyanie vitamina E na atrofiyu vlagalishcha u zhenshchin v postmenopauze // Tsenite zdorov'e. — 2014. — T. 17. — A750Bouzid D. Merzouki S. Bachiri M. Ailane S.E. Zerroug M.M. Vitamin D 3 a new drug against Candida albicans Journal de Mycologie Médicale 2016 11 79 82 27 1 10.1016/j.mycmed.2016.10.003Badalian Samuel S. Rosenbaum Paula F. Vitamin D and Pelvic Floor Disorders in Women Obstetrics & Gynecology 2010 03 795 803 115 4 10.1097/aog.0b013e3181d34806Morozova Yulia E. Tarasova Marina A. The physiological role of vitamin D and the significance of its deficiency in the pathogenesis of climacteric syndrome Journal of obstetrics and women's diseases 2018 07 74 82 67 3 10.17816/jowd67374-82Kotsur Yu.M., Flisyuk E.V. Sovremennye polimery v tekhnologii tabletok s prolongirovannym vysvobozhdeniem // Formuly farmatsii. — T. 2. — №1. — S. 36-43De Niet S, Coffiner M, Da Silva S, et al. A Randomized Study to Compare a Monthly to a Daily Administration of Vitamin D₃ Supplementation. Nutrients. 2018;10(6):659Malihi Z, Lawes CMM, Wu Z, Huang Y, et al. Monthly high-dose vitamin D supplementation does not increase kidney stone risk or serum calcium: results from a randomized controlled trial. Am J Clin Nutr. 2019;109(6):1578-1587Karampela I, Sakelliou A, Vallianou N, et al. Vitamin D and Obesity: Current Evidence and Controversies. Curr Obes Rep. 2021;10(2):162-180Belaya Zh.E., Pigarova E.A., Rozhinskaya L.Ya., i dr. Rezolyutsiya natsional'nogo mezhdistsiplinarnogo soveta ekspertov «Primenenie vysokodoznogo vitamina D dlya profilaktiki i lecheniya defitsita vitamina D, v tom chisle u komorbidnykh patsientov v praktike endokrinologov, revmatologov, gerontologov i terapevtov/ VOP» // Osteoporoz i osteopatii. — 2024. — T. 27. — №1. — S. 10-20. doi: https://doi.org/10.14341/osteo13171Lesnyak O. M. Nikitinskaya O. A. Toroptsova N. V. Belaya Zh. E. Belova K. Yu. Bordakova E. V. Gilmanov A. Zh. Gurkina E. Yu. Dorofeikov V. V. Ershova O. B. Zazerskaya I. E. Zotkin E. G. Karonova T. L. Marchenkova L. A. Nazarova A. V. Pigarova E. A. Rozhinskaya L. Ya. Safonova Yu. A. Skripnikova I. A. Shirinyan L. V. Yureneva S. V. Yakushevskaya O. V. THE PREVENTION, DIAGNOSIS, AND TREATMENT OF VITAMIN D AND CALCIUM DEFICIENCIES IN THE ADULT POPULATION OF RUSSIA AND IN PATIENTS WITH OSTEOPOROSIS (ACCORDING TO THE MATERIALS OF PREPARED CLINICAL RECOMMENDATIONS) Rheumatology Science and Practice 2015 09 403 53 4 10.14412/1995-4484-2015-403-408Rizzoli R. Boonen S. Brandi M.-L. Bruyère O. Cooper C. Kanis J.A. Kaufman J.-M. Ringe J.D. Weryha G. Reginster J.-Y. Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion 2013 01 305 313 29 4 10.1185/03007995.2013.766162Mel'nichenko G.A., Namazova-Baranova L.S., i soavt. Profilaktika i lechenie defitsita vitamina D: vybor optimal'nogo podkhoda // Voprosy sovremennoi pediatrii. — 2021. — T. 20. — №4. — S. 338-345

The authors declare that there are no conflicts of interest present.