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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl13684</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-13684</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая эндокринология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical endocrinology</subject></subj-group></article-categories><title-group><article-title>Ассоциация витилиго с эндокринными аутоиммунными заболеваниями: обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Association of vitiligo with endocrine autoimmune diseases: literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4290-3182</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рагимов</surname><given-names>М. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Ragimov</surname><given-names>M. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рагимов Магомедкерим Разинович, к.м.н.</p><p>129110, г. Москва, ул. Щепкина, д.61/2</p></bio><bio xml:lang="en"><p>Magomedkerim R. Ragimov, PhD</p><p>129110, Moscow, st. Shchepkina, 61/2</p></bio><email xlink:type="simple">tga.endocrine@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-7306-2581</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юзбекова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuzbekova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юзбекова Аида Артуровна</p><p>Москва</p></bio><bio xml:lang="en"><p>Aida A. Yuzbekova, PhD</p><p>Moscow</p></bio><email xlink:type="simple">yuzbekova02@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6456-998X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Молочков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Molochkov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Молочков Антон Владимирович, д.м.н., профессор</p><p>Москва</p></bio><bio xml:lang="en"><p>Anton V. Molochkov, PhD</p><p>Moscow</p></bio><email xlink:type="simple">antmd@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1668-8711</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мисникова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Misnikova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мисникова Инна Владимировна, д.м.н.</p><p>Москва</p></bio><bio xml:lang="en"><p>Inna V. Misnikova, PhD</p><p>Moscow</p></bio><email xlink:type="simple">inna-misnikova@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research and Clinical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Центральная государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского; Федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research and Clinical Institute; Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>08</day><month>09</month><year>2026</year></pub-date><volume>72</volume><issue>4</issue><fpage>40</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рагимов М.Р., Юзбекова А.А., Молочков А.В., Мисникова И.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Рагимов М.Р., Юзбекова А.А., Молочков А.В., Мисникова И.В.</copyright-holder><copyright-holder xml:lang="en">Ragimov M.R., Yuzbekova A.A., Molochkov A.V., Misnikova I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/13684">https://www.probl-endojournals.ru/jour/article/view/13684</self-uri><abstract><p>Витилиго — дерматологическое заболевание, проявляющееся очаговым исчезновением пигмента меланина на кожных покровах и слизистых оболочках человека. Несмотря на разнообразие предложенных гипотез развития данной патологии, центральная роль принадлежит именно аутоиммунному механизму поражения меланоцитов.</p><p>Анализ результатов многочисленных международных исследований подтверждает выраженную тенденцию к увеличению распространенности эндокринных аутоиммунных заболеваний (АИЗ) среди больных витилиго по сравнению с общей популяцией. К таким заболеваниям относятся, прежде всего, аутоиммунный тиреоидит (АИТ), болезнь Грейвса, сахарный диабет 1 типа (СД1) и первичная надпочечниковая недостаточность (ПНН).</p><p>Ассоциация многих из этих АИЗ, включая витилиго, с определенными гаплотипами HLA коррелирует с тем, что они входят в состав нескольких типов аутоиммунного полигландулярного синдрома (АПС). Отдельные исследования подтверждают высокую частоту сочетания витилиго с АПС 2, 3 и 4 типов.</p><p>Настоящий обзор направлен на систематизацию имеющейся научной литературы относительно частоты встречаемости и особенностей ассоциированных аутоиммунных эндокринных нарушений у лиц, страдающих витилиго.</p></abstract><trans-abstract xml:lang="en"><p>Vitiligo is a dermatological disease characterized by focal disappearance of the melanin pigment on the skin and mucous membranes of a person. Despite the variety of proposed hypotheses for the development of this pathology, the central role belongs to the autoimmune mechanism of melanocyte damage.</p><p>Analysis of the results of numerous international studies confirms a pronounced tendency towards an increase in the prevalence of endocrine autoimmune diseases among patients with vitiligo compared to the general population. Such diseases include, first of all, autoimmune thyroiditis, Graves' disease, type I diabetes mellitus and autoimmune adrenal insufficiency. Some studies confirm a high frequency of vitiligo combination with multiendocrine autoimmune syndromes.</p><p>This review is aimed at systematizing the available scientific literature on the frequency of occurrence and characteristics of associated autoimmune endocrine disorders in individuals suffering from vitiligo.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>витилиго</kwd><kwd>аутоиммунный сахарный диабет</kwd><kwd>эндокринные заболевания</kwd><kwd>меланоциты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vitiligo</kwd><kwd>autoimmune diabetes mellitus</kwd><kwd>endocrine diseases</kwd><kwd>melanocytes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pathak GN, Tan IJ, Bai G, Dhillon J, Rao BK. 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