problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl13688problendo-13688Research ArticleКлиническая эндокринологияClinical endocrinologyТиротоксический криз у пациентки с сочетанием болезни Грейвса и сахарного диабета 1 типаThyrotoxic crisis in a patient with coexisting Graves’ disease and type 1 diabetes mellitushttps://orcid.org/0000-0003-0560-8843ДаниловаЛ. И.DanilovaL. I.

Данилова Лариса Ивановна, д.м.н., профессор

Минск

Larisa I. Danilova, MD, PhD, Professor

Minsk

Larisa.dan@gmail.comhttps://orcid.org/0000-0002-7679-0032КороленкоГ. Г.KorolenkoG. G.

Короленко Галина Георгиевна, к.м.н., доцент

220096, Минск, ул. Уборевича, д. 73

 

 

Galina G. Korolenko, MD, PhD

Uborevich street, 220096 Minsk

korolenko.g@gmail.comhttps://orcid.org/0000-0002-5258-9182ЛущикМ. Л.LushchykM. L.

Лущик Максим Леонидович, к.м.н., доцент

Минск

Maxim L. Lushchyk, MD, PhD

Minsk

maxim.lushchyk@gmail.comhttps://orcid.org/0009-0008-4538-5780ЧаплинскаяО. В.ChaplinskayaO. V.

Чаплинская Ольга Владимировна

Гомель

Olga V. Chaplinskaya

Gomel

O_liri@mail.ruhttps://orcid.org/0009-0004-5063-3786БуркоИ. И.BourkoI. I.

Бурко Ирина Ивановна, к.м.н., доцент

Минск

 

Irina I. Bourko, MD, PhD

Minsk

bourko@mail.ruБелорусский государственный медицинский университетБеларусьBelarusian State Medical UniversityBelarusГомельская городская клиническая больница №3БеларусьGomel City Clinical Hospital №3Belarus2026080920267244652Copyright © Данилова Л.И., Короленко Г.Г., Лущик М.Л., Чаплинская О.В., Бурко И.И., 20262026Данилова Л.И., Короленко Г.Г., Лущик М.Л., Чаплинская О.В., Бурко И.И.Danilova L.I., Korolenko G.G., Lushchyk M.L., Chaplinskaya O.V., Bourko I.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/13688

Тиротоксический криз (ТК) представляет собой редкое, но потенциально жизнеугрожающее осложнение декомпенсированного тиротоксикоза, требующее немедленного вмешательства. Диагностика ТК основывается на выраженной клинической картине тяжелого гипертиреоза в сочетании с провоцирующими факторами. Терапию следует начинать при первых подозрениях на развитие криза, без ожидания результатов гормонального анализа, получение которых может занять значительное время. В статье представлен клинический случай пациентки с сочетанием болезни Грейвса и сахарного диабета 1 типа, у которой ТК был своевременно распознан и эффективно купирован. Провоцирующим фактором выступил диабетический кетоацидоз. Описанный случай подчеркивает важность ранней диагностики и интенсивной терапии для улучшения прогноза при ТК.

Thyrotoxic crisis (TC) is a rare but potentially life-threatening complication of decompensated thyrotoxicosis that requires immediate medical intervention. The diagnosis of TC is based on a clinical picture of severe hyperthyroidism in combination with precipitating factors. Treatment should be initiated at the first suspicion of crisis development, without waiting for the results of hormonal analysis, which may take considerable time to obtain. This article presents a clinical case of a female patient with coexisting Graves’ disease and type 1 diabetes mellitus, in whom TC was promptly recognized and effectively managed. The precipitating factor was diabetic ketoacidosis. This case highlights the importance of early diagnosis and intensive therapy to improve the prognosis of patients with TC.

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The authors declare that there are no conflicts of interest present.