problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl13694problendo-13694Research ArticleРепродуктивная эндокринологияReproductive EndocrinologyРоссийские критерии приемлемости назначения менопаузальной гормональной терапии пациенткам с сердечно-сосудистыми и метаболическими заболеваниями. Согласительный документ РКО, РОАГ, РАЭ, ЕАТ, АФР, РНМОТ, РАГГRussian eligibility criteria for prescription of menopausal hormone therapy to patients with cardiovascular and metabolic diseases. Agreement document of RKO, ROAG, RAE, EAT, AFR, RNMOT, RAGGhttps://orcid.org/0000-0003-2929-0980ШляхтоЕ. В.ShlyakhtoE. V.

Шляхто Евгений Владимирович, д.м.н., профессор 

Evgeny V. Shlyakhto, MD, PhD, Professor

info@scardio.ruhttps://orcid.org/0000-0002-8175-7886ДедовИ. И.DedovI. I.

Дедов Иван Иванович, д.м.н., профессор 

Ivan I. Dedov, MD, PhD, Professor

info@rae-org.ruhttps://orcid.org/0000-0003-2976-7128СеровВ. Н.SerovV. N.

Серов Владимир Николаевич, д.м.н., профессор 

Vladimir N. Serov, MD, PhD, Professor

v_serov@oparina4.ruhttps://orcid.org/0000-0002-7712-1260СухихГ. Т.SukhikhG. T.

Сухих Геннадий Тихонович, д.м.н., профессор 

Gennady T. Sukhikh, MD, PhD, Professor

secretariat@oparina4.ruhttps://orcid.org/0000-0002-6645-2515АрутюновГ. П.ArutyunovG. P.

Арутюнов Григорий Павлович, д.м.н., профессор 

Grigory P. Arutyunov, MD, PhD, Professor

arut@ossn.ruСучковИ. А.SuchkovI. A.

Сучков Игорь Александрович, д.м.н., профессор 

Igor A. Suchkov, MD, PhD, Professor

suchkov_med@mail.ruhttps://orcid.org/0000-0002-4453-8430ДрапкинаО. М.DrapkinaO. M.

Драпкина Оксана Михайловна, член-корреспондент РАН, д.м.н., профессор 

Oksana M. Drapkina, MD, PhD, Professor

drapkina@bk.ruhttps://orcid.org/0000-0002-4193-688XТкачеваО. Н.TkachevaO. N.

Ткачева Ольга Николаевна, д.м.н., профессор 

Olga N. Tkacheva, MD, PhD, Professor

tkacheva@rgnkc.ruhttps://orcid.org/0000-0002-8160-5612ОрловаЯ. А.OrlovaYa. A.

Орлова Яна Артуровна, д.м.н. 

Yana A. Orlova, MD, PhD

5163002@bk.ruhttps://orcid.org/0000-0002-9813-2823БарановИ. И.BaranovI. I.

Баранов Игорь Иванович, д.м.н., профессор 

Igor I. Baranov, MD, Dr. Sc. (Med.)

I_baranov@oparina4.ruhttps://orcid.org/0000-0001-8425-0020АндрееваЕ. Н.AndreevaE. N.

Андреева Елена Николаевна, д.м.н., профессор 

Elena N. Andreeva, MD, PhD, Professor

endogin@mail.ruhttps://orcid.org/0000-0003-2864-066XЮреневаС. В.YurenevaS. V.

Юренева Светлана Владимировна, д.м.н., профессор 

Svetlana V. Yureneva, MD, PhD, Professor

syureneva@gmail.comhttps://orcid.org/0000-0002-6551-4147ЯрмолинскаяМ. И.YarmolinskayaM. I.

Ярмолинская Мария Игоревна, д.м.н., профессор 

Maria I. Yarmolinskaya, MD, PhD, Professor

m.yarmolinskaya@gmail.comhttps://orcid.org/0000-0002-0627-3902СметникА. А.SmetnikA. A.

Сметник Антонина Александровна, к.м.н. 

Antonina A. Smetnik, MD, PhD

asmetnik@gmail.comhttps://orcid.org/0000-0001-7652-2962ВиллевальдеС. В.VillevaldeS. V.

Виллевалде Светлана Вадимовна, д.м.н. 

Svetlana V. Villevalde, MD, PhD, Professor

villevaldes@mail.ruhttps://orcid.org/0000-0001-7003-5186КозиоловаН. А.KoziolovaN. A.

Козиолова Наталья Андреевна, д.м.н., профессор 

Natalya A. Koziolova, MD, PhD, Professor

nakoziolova@mail.ruhttps://orcid.org/0000-0003-1534-3965СергиенкоИ. В.SergienkoI. V.

Сергиенко Игорь Владимирович, д.м.н., профессор 

Igor V. Sergienko, MD, PhD, Professor

igorcardio@mail.ruhttps://orcid.org/0000-0003-2816-1183ЯвеловИ. С.YavelovI. S.

Явелов Игорь Семенович, д.м.н., профессор 

Igor S. Yavelov, MD, PhD, Professor

yavelov@yahoo.comhttps://orcid.org/0000-0002-8656-3191ИртюгаО. Б.IrtyugaO. B.

Иртюга Ольга Борисовна, д.м.н., профессор 

Olga B. Irtyuga

olgir@yandex.ruhttps://orcid.org/0000-0003-4979-7420ГригорянО. П.GrigoryanO. R.

Григорян Ольга Рафаэльевна, д.м.н., профессор 

Оlga R. Grigoryan, MD, PhD, Professor

iceberg1995@mail.ruhttps://orcid.org/0000-0001-7891-6850ДудинскаяЕ. Н.DudinskayaE. N.

Дудинская Екатерина Наильевна, д.м.н. 

Ekaterina N. Dudinskaya, MD, PhD

katharina.gin@gmail.comhttps://orcid.org/0000-0002-6563-0471ЗолотухинИ. А.ZolotukhinI. A.

Золотухин Игорь Анатольевич, д.м.н, профессор 

Igor A.Zolotukhin, MD, PhD, Professor

ИлюхинЕ. А.IlyukhinЕ. А.

Илюхин Евгений Аркадьевич, к.м.н. 

Evgeniy A. Ilyukhin, MD, PhD

iluhin-e@yandex.ru202518012026716108137Copyright © Шляхто Е.В., Дедов И.И., Серов В.Н., Сухих Г.Т., Арутюнов Г.П., Сучков И.А., Драпкина О.М., Ткачева О.Н., Орлова Я.А., Баранов И.И., Андреева Е.Н., Юренева С.В., Ярмолинская М.И., Сметник А.А., Виллевальде С.В., Козиолова Н.А., Сергиенко И.В., Явелов И.С., Иртюга О.Б., Григорян О.П., Дудинская Е.Н., Золотухин И.А., Илюхин Е.А., 20262026Шляхто Е.В., Дедов И.И., Серов В.Н., Сухих Г.Т., Арутюнов Г.П., Сучков И.А., Драпкина О.М., Ткачева О.Н., Орлова Я.А., Баранов И.И., Андреева Е.Н., Юренева С.В., Ярмолинская М.И., Сметник А.А., Виллевальде С.В., Козиолова Н.А., Сергиенко И.В., Явелов И.С., Иртюга О.Б., Григорян О.П., Дудинская Е.Н., Золотухин И.А., Илюхин Е.А.Shlyakhto E.V., Dedov I.I., Serov V.N., Sukhikh G.T., Arutyunov G.P., Suchkov I.A., Drapkina O.M., Tkacheva O.N., Orlova Y.A., Baranov I.I., Andreeva E.N., Yureneva S.V., Yarmolinskaya M.I., Smetnik A.A., Villevalde S.V., Koziolova N.A., Sergienko I.V., Yavelov I.S., Irtyuga O.B., Grigoryan O.R., Dudinskaya E.N., Zolotukhin I.A., Ilyukhin Е.А.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/13694

Климактерические симптомы могут нарушать ход жизни женщин на пике карьеры и семейной жизни. В настоящее время самым эффективным методом лечения этих проявлений является менопаузальная гормональная терапия (МГТ). Наличие сердечно-сосудистых и метаболических заболеваний не исключает возможность назначения МГТ с целью купирования климактерических симптомов и улучшения качества жизни. Однако нередко препятствием для использования этого вида гормональной терапии являются опасения врачей, которые боятся принести пациенткам больше вреда, чем пользы. Осторожность особенно важна, когда речь идет о женщинах, страдающих сопутствующими заболеваниями. Более того, следует признать, что качественных исследований относительно безопасности МГТ при основных хронических неинфекционных заболеваниях и часто встречаемых коморбидных состояниях недостаточно. В представленном согласительном документе проведен анализ всех доступных в настоящее время данных, полученных в ходе клинических исследований различного дизайна, и создан свод критериев приемлемости назначения МГТ женщинам с сопутствующими сердечно-сосудистыми и метаболическими заболеваниями. Опираясь на представленный документ, врачи различных специальностей, консультирующие женщин в климактерии, получат доступный алгоритм, позволяющий избегать потенциально опасных ситуаций и обоснованно назначать МГТ в клинической практике.

Menopausal symptoms can disrupt the lives of women at the peak of their careers and family life. Currently, the most effective treatment for these symptoms is menopausal hormone therapy (MHT). The presence of cardiovascular and metabolic diseases does not preclude the use of MHT to relieve menopausal symptoms and improve quality of life. However, physicians’ concerns about causing more harm than good often hinder the use of this type of hormone therapy. Caution is especially important when it comes to women with comorbidities. Moreover, it should be acknowledged that high-quality studies on the safety of MHT for major chronic noncommunicable diseases and common comorbid conditions are insufficient. This consensus document analyzes all currently available data from clinical trials of various designs and develops a set of eligibility criteria for prescribing MHT to women with comorbid cardiovascular and metabolic diseases. Based on this document, physicians of various specialties who consult with women in menopause will receive an accessible algorithm that will allow them to avoid potentially dangerous situations and appropriately prescribe HRT in clinical practice.

менопаузальная гормональная терапиясердечно-сосудистые заболеванияметаболические заболеваниясахарный диабетвенозные тромбоэмболические осложненияmenopausal hormone therapycardiovascular diseasesmetabolic diseasesdiabetesvenous thromboembolic complicationsPravitel'stvo Rossiiskoi Federatsii. Rasporyazhenie Pravitel'stva Rossiiskoi Federatsii ot 29.12.2022 № N 4356-p “Ob utverzhdenii Natsional'noi strategii deistvii v interesakh zhenshchin na 2023—2030 gody”. Dostupno na: https://www.consultant.ru/document/cons_doc_LAW_.Ulumbekova G.E., Khudova I.Yu. Otsenka demograficheskogo, sotsial'nogo i ekonomicheskogo effekta pri prieme menopauzal'noi gormonal'noi terapii. ORGZDRAV: novosti, mneniya, obucheniya. Vestnik VShOUZ. 2020;6(4(22)):23–53. doi: https://doi.org/10.24411/2411-8621-2020-14002Lambrinoudaki Irene Armeni Eleni Goulis Dimitrios Bretz Silvia Ceausu Iuliana Durmusoglu Fatih Erkkola Risto Fistonic Ivan Gambacciani Marco Geukes Marije Hamoda Haitham Hartley Caiomhe Hirschberg Angelica Lindén Meczekalski Blazej Mendoza Nicolas Mueck Alfred Smetnik Antonina Stute Petra van Trotsenburg Mick Rees Margaret Menopause, wellbeing and health: A care pathway from the European Menopause and Andropause Society Maturitas 2022 05 1 14 163 10.1016/j.maturitas.2022.04.008Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Klinicheskie rekomendatsii. Menopauza i klimaktericheskoe sostoyanie u zhenshchiny. 2021. Dostupno na: https://cr.minzdrav.gov.ru/previewcr/117_2Harlow Siobán D. Gass Margery Hall Janet E. Lobo Roger Maki Pauline Rebar Robert W. Sherman Sherry Sluss Patrick M. de Villiers Tobie J. Executive summary of the Stages of Reproductive Aging Workshop + 10 Menopause 2012 03 387 395 19 4 10.1097/gme.0b013e31824d8f40Drewe Juergen Bucher Kathleen A Zahner Catherine A systematic review of non-hormonal treatments of vasomotor symptoms in climacteric and cancer patients SpringerPlus 2015 02 4 1 10.1186/s40064-015-0808-ySchnatz Peter F. Romegialli Alison Abrantes Jessica Marakovits Kimberly Cunningham David O'Sullivan David M. The North American Menopause Society Menopause 2008 09 996 1001 15 5 10.1097/gme.0b013e318166f026Paramsothy Pangaja Harlow Siobán D. Nan Bin Greendale Gail A. Santoro Nanette Crawford Sybil L. Gold Ellen B. Tepper Ping G. Randolph John F. Duration of the menopausal transition is longer in women with young age at onset: the multiethnic Study of Women's Health Across the Nation Menopause 2016 09 142 149 24 2 10.1097/gme.0000000000000736Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Menopauzal'naya gormonoterapiya i sokhranenie zdorov'ya zhenshchin v zrelom vozraste. Klinicheskie rekomendatsii. 2015. Dostupno na: https://www.consultant.ru/document/cons_doc_LAW_320073Schoenaker Danielle AJM Jackson Caroline A Rowlands Jemma V Mishra Gita D Socioeconomic position, lifestyle factors and age at natural menopause: a systematic review and meta-analyses of studies across six continents International Journal of Epidemiology 2014 04 1542 1562 43 5 10.1093/ije/dyu094Freeman Ellen W. Sammel Mary D. Sanders Richard J. Risk of long-term hot flashes after natural menopause Menopause 2014 01 924 932 21 9 10.1097/gme.0000000000000196Costanian C. Zangiabadi S. Bahous S. A. Deonandan R. Tamim H. Reviewing the evidence on vasomotor symptoms: the role of traditional and non-traditional factors Climacteric 2020 01 213 223 23 3 10.1080/13697137.2019.1711051Prior JC. Progesterone for Symptomatic Perimenopause Treatment - Progesterone politics, physiology and potential for perimenopause. Facts, Views & Vision in ObGyn. 2011;3(2):109–20. PMID: 24753856Santoro Nanette Epperson C. Neill Mathews Sarah B. Menopausal Symptoms and Their Management Endocrinology and Metabolism Clinics of North America 2015 08 497 515 44 3 10.1016/j.ecl.2015.05.001Mel'nichenko Galina A. Belaya Zhanna E. Rozhinskaya Lyudmila Ya. Toroptsova Natalia V. Alekseeva Lyudmila I. Biryukova Elena V. Grebennikova Tatiana A. Dzeranova Larisa K. Dreval Aleksandr V. Zagorodniy Nikolay V. Il'yin Aleksandr V. Kryukova Irina V. Lesnyak Ol’ga M. Mamedova Elizaveta O. Nikitinskaya Oksana A. Pigarova Ekaterina A. Rodionova Svetlana S. Skripnikova Irina A. Tarbaeva Natalia V. Farba Leonid Ya. Tsoriev Timur T. Chernova Tatiana O. Yureneva Svetlana V. Yakushevskaya Oksana V. Dedov Ivan I. Russian federal clinical guidelines on the diagnostics, treatment, and prevention of osteoporosis Problems of Endocrinology 2018 02 392 426 63 6 10.14341/probl2017636392-426Muka Taulant Oliver-Williams Clare Colpani Veronica Kunutsor Setor Chowdhury Susmita Chowdhury Rajiv Kavousi Maryam Franco Oscar H. Association of Vasomotor and Other Menopausal Symptoms with Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis PLOS ONE 2016 06 e0157417 11 6 10.1371/journal.pone.0157417Baber R. J. Panay N. Fenton A. 2016 IMS Recommendations on women’s midlife health and menopause hormone therapy Climacteric 2016 02 109 150 19 2 10.3109/13697137.2015.1129166Kaufman Melissa R. Ackerman A. Lenore Amin Katherine A. Coffey Marge Danan Elisheva Faubion Stephanie S. Hardart Anne Goldstein Irwin Ippolito Giulia M. Northington Gina M. Powell Charles R. Rubin Rachel S. Westney O. Lenaine Wilson Tracey S. Lee Una J. The AUA/SUFU/AUGS Guideline on Genitourinary Syndrome of Menopause Journal of Urology 2025 04 242 250 214 3 10.1097/ju.0000000000004589The 2020 genitourinary syndrome of menopause position statement of The North American Menopause Society Menopause 2020 08 976 992 27 9 10.1097/gme.0000000000001609Rueda C. Osorio A. M. Avellaneda A. C. Pinzón C. E. Restrepo O. I. The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review Climacteric 2017 06 321 330 20 4 10.1080/13697137.2017.1329291Hirschberg Angelica Lindén Bitzer Johannes Cano Antonio Ceausu Iuliana Chedraui Peter Durmusoglu Fatih Erkkola Risto Goulis Dimitrios G. Kiesel Ludwig Lopes Patrice Pines Amos van Trotsenburg Mick Lambrinoudaki Irene Rees Margaret Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide Maturitas 2021 04 55 61 148 10.1016/j.maturitas.2021.04.005Weidlinger S. Schmutz C. Janka H. Gruetter C. Stute P. Sustainability of vaginal estrogens for genitourinary syndrome of menopause – a systematic review Climacteric 2021 03 551 559 24 6 10.1080/13697137.2021.1891218Matarazzo Maria Grazia Sarpietro Giuseppe Fiorito Debora Di Pasqua Salvatore Ingrassano Simona Panella Marco Marzio Cianci Antonio Caruso Salvatore Intravaginal 6.5 mg prasterone administration in postmenopausal women with overactive bladder syndrome: A pilot study European Journal of Obstetrics & Gynecology and Reproductive Biology 2021 06 67 71 263 10.1016/j.ejogrb.2021.06.009Duarte Pablo Romero Maroto Martín María Teresa Mar Martín Moya María del Prados Pedro Abad Quality of life analysis measured with the Cervantes 16 scale in treated menopausal women with genitourinary syndrome Journal of Comparative Effectiveness Research 2022 11 1365 1374 11 18 10.2217/cer-2022-0086Labrie Fernand Intracrinology and menopause: the science describing the cell-specific intracellular formation of estrogens and androgens from DHEA and their strictly local action and inactivation in peripheral tissues Menopause 2018 08 220 224 26 2 10.1097/gme.0000000000001177Labrie Fernand Archer David F. Koltun William Vachon Andrée Young Douglas Frenette Louise Portman David Montesino Marlene Côté Isabelle Parent Julie Lavoie Lyne BSc Adam Beauregard Martel Céline Vaillancourt Mario Balser John Moyneur Érick Efficacy of intravaginal dehydroepiandrosterone (DHEA) on moderate to severe dyspareunia and vaginal dryness, symptoms of vulvovaginal atrophy, and of the genitourinary syndrome of menopause Menopause 2018 10 1339 1353 25 11 10.1097/gme.0000000000001238Labrie Fernand Archer David F. Martel Céline Vaillancourt Mario Montesino Marlene Combined data of intravaginal prasterone against vulvovaginal atrophy of menopause Menopause 2017 06 1246 1256 24 11 10.1097/gme.0000000000000910Cappola Anne R Auchus Richard J El-Hajj Fuleihan Ghada Handelsman David J Kalyani Rita R McClung Michael Stuenkel Cynthia A Thorner Michael O Verbalis Joseph G Hormones and Aging: An Endocrine Society Scientific Statement The Journal of Clinical Endocrinology & Metabolism 2023 06 1835 1874 108 8 10.1210/clinem/dgad225Joint position of Russian experts on the clinical significance of hyperandrogenism in early postmenopausal women Akusherstvo i ginekologiia 2025 06 201 201 5_2025 10.18565/aig.2025.118Gluvic Zoran Zaric Bozidarka Resanovic Ivana Obradovic Milan Mitrovic Aleksandar Radak Djordje Isenovic Esma Link between Metabolic Syndrome and Insulin Resistance Current Vascular Pharmacology 2016 11 30 39 15 1 10.2174/1570161114666161007164510Metabolic Syndrome and Menopause Advances in Clinical Chemistry 2015 08 1 75 10.1016/bs.acc.2015.07.001Hirschberg Angelica Lindén Hyperandrogenism and Cardiometabolic Risk in Pre- and Postmenopausal Women—What Is the Evidence? The Journal of Clinical Endocrinology & Metabolism 2023 10 1202 1213 109 5 10.1210/clinem/dgad590Hirschberg Angelica Lindén Approach to Investigation of Hyperandrogenism in a Postmenopausal Woman The Journal of Clinical Endocrinology & Metabolism 2022 11 1243 1253 108 5 10.1210/clinem/dgac673Frederiksen Hanne Johannsen Trine Holm Andersen Stine Ehlern Petersen Jørgen Holm Busch Alexander Siegfried Ljubicic Marie Lindhardt Fischer Margit Bistrup Upners Emmie N. Hagen Casper P. Main Katharina M. Aksglaede Lise Jørgensen Niels Lund Kårhus Line Linneberg Allan Andersson Anna-Maria Flück Christa E. Juul Anders Sex- and age-specific reference intervals of 16 steroid metabolites quantified simultaneously by LC-MS/MS in sera from 2458 healthy subjects aged 0 to 77 years Clinica Chimica Acta 2024 07 119852 562 10.1016/j.cca.2024.119852Torréns Javier I. Sutton-Tyrrell Kim Zhao Xinhua Matthews Karen Brockwell Sarah Sowers MaryFran Santoro Nanette Relative androgen excess during the menopausal transition predicts incident metabolic syndrome in midlife women Menopause 2009 05 257 264 16 2 10.1097/gme.0b013e318185e249Alemany Marià The Roles of Androgens in Humans: Biology, Metabolic Regulation and Health International Journal of Molecular Sciences 2022 10 11952 23 19 10.3390/ijms231911952Galmés-Pascual Bel M. Martínez-Cignoni Melanie Raquel Morán-Costoya Andrea Bauza-Thorbrügge Marco Sbert-Roig Miquel Valle Adamo Proenza Ana M. Lladó Isabel Gianotti Magdalena 17β-estradiol ameliorates lipotoxicity-induced hepatic mitochondrial oxidative stress and insulin resistance Free Radical Biology and Medicine 2020 02 148 160 150 10.1016/j.freeradbiomed.2020.02.016Nestler John E. Jakubowicz Daniela J. Falcon de Vargas Aida Brik Carlos Quintero Nitza Medina Francisco Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System1 The Journal of Clinical Endocrinology & Metabolism 2014 01 2001 2005 83 6 10.1210/jcem.83.6.4886Xing Chuan Zhang Jiaqi Zhao Han He Bing Effect of Sex Hormone-Binding Globulin on Polycystic Ovary Syndrome: Mechanisms, Manifestations, Genetics, and Treatment International Journal of Women's Health 2022 02 91 105 Volume 14 10.2147/ijwh.s344542Dicker A. Rydén M. Näslund E. Muehlen I. E. Wirén M. Lafontan M. Arner P. Effect of testosterone on lipolysis in human pre-adipocytes from different fat depots Diabetologia 2004 03 420 428 47 3 10.1007/s00125-003-1324-0Zang Hong Rydén Mikael Wåhlen Kerstin Dahlman-Wright Karin Arner Peter Hirschberg Angelica Lindén Effects of testosterone and estrogen treatment on lipolysis signaling pathways in subcutaneous adipose tissue of postmenopausal women Fertility and Sterility 2007 04 100 106 88 1 10.1016/j.fertnstert.2006.11.088Grundy Scott M. Metabolic Syndrome: A Multiplex Cardiovascular Risk Factor The Journal of Clinical Endocrinology & Metabolism 2007 02 399 404 92 2 10.1210/jc.2006-0513 Hu G. Gender difference in all-cause and cardiovascular mortality related to hyperglycaemia and newly-diagnosed diabetes Diabetologia 2016 10 608 617 46 5 10.1007/s00125-003-1096-6Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Klinicheskie rekomendatsii. Sakharnyi diabet 2 tipa u vzroslykh. 2022. Dostupno na: https://cr.minzdrav.gov.ru/preview-cr/290_2Zhang Lulu Bao Lei Li Yuqian Wang Chongjian Dong Xiaokang Abdulai Tanko Yang Xiu Fan Mengying Cui Songyang Zhou Wen Mao Zhenxing Huo Wenqian Wei Dandan Li Linlin Age at menopause, body mass index, and risk of type 2 diabetes mellitus in postmenopausal Chinese women: The Henan Rural Cohort study Nutrition, Metabolism and Cardiovascular Diseases 2020 04 1347 1354 30 8 10.1016/j.numecd.2020.04.003Opoku Albert A. Abushama Mandy Konje Justin C. Obesity and menopause Best Practice & Research Clinical Obstetrics & Gynaecology 2023 05 102348 88 10.1016/j.bpobgyn.2023.102348Vishram Julie K. K. Borglykke Anders Andreasen Anne H. Jeppesen Jørgen Ibsen Hans Jørgensen Torben Palmieri Luigi Giampaoli Simona Donfrancesco Chiara Kee Frank Mancia Giuseppe Cesana Giancarlo Kuulasmaa Kari Salomaa Veikko Sans Susana Ferrieres Jean Dallongeville Jean Söderberg Stefan Arveiler Dominique Wagner Aline Tunstall-Pedoe Hugh Drygas Wojciech Olsen Michael H. Impact of Age and Gender on the Prevalence and Prognostic Importance of the Metabolic Syndrome and Its Components in Europeans. The MORGAM Prospective Cohort Project PLoS ONE 2014 09 e107294 9 9 10.1371/journal.pone.0107294Lizcano Fernando Guzmán Guillermo Estrogen Deficiency and the Origin of Obesity during Menopause BioMed Research International 2014 03 1 11 2014 10.1155/2014/757461Zhu Jing Zhou Yier Jin Bihui Shu Jing Role of estrogen in the regulation of central and peripheral energy homeostasis: from a menopausal perspective Therapeutic Advances in Endocrinology and Metabolism 2023 09 14 10.1177/20420188231199359Drapkina O. M. Kontsevaya A. V. Kalinina A. M. Avdeev S. M. Agaltsov M. V. Alexandrova L. M. Antsiferova A. A. Aronov D. M. Akhmedzhanov N. M. Balanova Yu. A. Balakhonova T. V. Berns S. A. Bochkarev M. V. Bochkareva E. V. Bubnova M. V. Budnevsky A. V. Gambaryan M. G. Gorbunov V. M. Gorny B. E. Gorshkov A. Yu. Gumanova N. G. Dadaeva V. A. Drozdova L. Yu. Egorov V. A. Eliashevich S. O. Ershova A. I. Ivanova E. S. Imaeva A. E. Ipatov P. V. Kaprin A. D. Karamnova N. S. Kobalava Zh. D. Konradi A. O. Kopylova O. V. Korostovtseva L. S. Kotova M. B. Kulikova M. S. Lavrenova E. A. Lischenko O. V. Lopatina M. V. Lukina Yu. V. Lukyanov M. M. Mayev I. V. Mamedov M. N. Markelova S. V. Martsevich S. Yu. Metelskaya V. A. Meshkov A. N. Milushkina O. Yu. Mukaneeva D. K. Myrzamatova A. O. Nebieridze D. V. Orlov D. O. Poddubskaya E. A. Popovich M. V. Popovkina O. E. Potievskaya V. I. Prozorova G. G. Rakovskaya Yu. S. Rotar O. P. Rybakov I. A. Sviryaev Yu. V. Skripnikova I. A. Skoblina N. A. Smirnova M. I. Starinsky V. V. Tolpygina S. N. Usova E. V. Khailova Zh. V. Shalnova S. A. Shepel R. N. Shishkova V. N. Yavelov I. S. 2022 Prevention of chronic non-communicable diseases in Of the Russian Federation. National guidelines Cardiovascular Therapy and Prevention 2022 05 3235 21 4 10.15829/1728-8800-2022-3235Yureneva Yureneva S.V. Obesity during the menopausal transition: how to break negative connections and prevent consequences? Akusherstvo i ginekologiia 2024 12 56 65 11_2024 10.18565/aig.2024.291Chen Guo-Chong Arthur Rhonda Iyengar Neil M Kamensky Victor Xue Xiaonan Wassertheil-Smoller Sylvia Allison Matthew A Shadyab Aladdin H Wild Robert A Sun Yangbo Banack Hailey R Chai Jin Choul Wactawski-Wende Jean Manson JoAnn E Stefanick Marcia L Dannenberg Andrew J Rohan Thomas E Qi Qibin Association between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index European Heart Journal 2019 05 2849 2855 40 34 10.1093/eurheartj/ehz391Ministry of Health of Russian Federation. Clinical recommendations. Obesity. 2024. Av. at: https://cr.minzdrav.gov.ru/preview-cr/28_3]. [Russian: Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Klinicheskie rekomendatsii. Ozhirenie. 2024. Dostupno na: https://cr.minzdrav.gov.ru/preview-cr/28_3]Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Klinicheskie rekomendatsii. Arterial'naya gipertenziya u vzroslykh. 2024. Dostupno na: https://cr.minzdrav.gov.ru/preview-cr/62_3Alberti K George MM Zimmet Paul Shaw Jonathan The metabolic syndrome—a new worldwide definition The Lancet 2005 09 1059 1062 366 9491 10.1016/s0140-6736(05)67402-8Wang Juan Wu Daichao Guo Hui Li Meixiang Hyperandrogenemia and insulin resistance: The chief culprit of polycystic ovary syndrome Life Sciences 2019 10 116940 236 10.1016/j.lfs.2019.116940Cushman Mary Estrogen Plus Progestin and Risk of Venous Thrombosis JAMA 2004 10 1573 292 13 10.1001/jama.292.13.1573Troshina E.A., Pokusaeva V.N., Andreeva E.N. Ozhirenie u zhenshchin. pod red. Mel'nichenko G.A., Nikiforovskogo N.K.- M.: OOO Meditsinskoe informatsionnoe agentstvo; 2017. – 272s ISBN 978-5-9986-0296-2Caprio Massimiliano Antelmi Antonella Chetrite Gérard Muscat Adeline Mammi Caterina Marzolla Vincenzo Fabbri Andrea Zennaro Maria-Christina Fève Bruno Antiadipogenic Effects of the Mineralocorticoid Receptor Antagonist Drospirenone: Potential Implications for the Treatment of Metabolic Syndrome Endocrinology 2010 11 113 125 152 1 10.1210/en.2010-0674Smetnik Smetnik A.A. Ivanov Ivanov I.A. Ermakova Ermakova E.I. Tabeeva Tabeeva G.I. Characteristics of menopausal hormone therapy use in Russia: results of a large-scale survey of peri- and postmenopausal women Akusherstvo i ginekologiia 2025 09 196 208 8_2025 10.18565/aig.2025.200Sukhikh G.T., Serov V.N., Shlyakhto E.V., Dedov I.I., Arutyunov G.P., Tkacheva O.N. i dr. Menopauzal'naya gormonal'naya terapiya u patsientok s serdechno-sosudistymi i metabolicheskimi zabolevaniyami: mezhdistsiplinarnyi del'fiiskii konsensus sredi rossiiskikh ginekologov, kardiologov, endokrinologov, gerontologov i geriatrov, flebologov, klinicheskikh farmakologov. Terapevticheskii arkhiv. 2026;98(1):6–27. doi: https://doi.org/10.26442/00403660.2026.01.203470Dedov I. I. Shestakova M. V. Vikulova O. K. Zheleznyakova A. V. Isakov M. А. Epidemiological characteristics of diabetes mellitus in the Russian Federation: clinical and statistical analysis according to the Federal diabetes register data of 01.01.2021 Diabetes mellitus 2021 09 204 221 24 3 10.14341/dm12759Salpeter S. R. Walsh J. M. E. Ormiston T. M. Greyber E. Buckley N. S. Salpeter E. E. Meta‐analysis: effect of hormone‐replacement therapy on components of the metabolic syndrome in postmenopausal women Diabetes, Obesity and Metabolism 2005 11 538 554 8 5 10.1111/j.1463-1326.2005.00545.xSchindler Adolf E. Campagnoli Carlo Druckmann René Huber Johannes Pasqualini Jorge R. Schweppe Karl W. Thijssen Jos H.H. Reprint of Classification and pharmacology of progestins Maturitas 2008 12 171 180 61 1-2 10.1016/j.maturitas.2008.11.013Mendoza Nicolás Ramírez Isabel de la Viuda Esther Coronado Pluvio Baquedano Laura Llaneza Plácido Nieto Verónica Otero Borja Sánchez-Méndez Sonia de Frutos Visitación Álvarez Andraca Leire Barriga Patricio Benítez Zully Bombas Teresa Cancelo Mª. Jesús Cano Antonio Branco Camil Castelo Correa Marta Doval José Luis Fasero María Fiol Gabriel Garello Nestor C. Genazzani Andrea R. Gómez Ana Isabel Gómez Mª. Ángeles González Silvia Goulis Dimitrios G. Guinot Misericordia Hernández Luis Rolando Herrero Sonia Iglesias Eva Jurado Ana Rosa Lete Iñaki Lubián Daniel Martínez Milagros Nieto Aníbal Nieto Laura Palacios Santiago Pedreira Milagros Pérez-Campos Ezequiel Plá María Jesús Presa Jesús Quereda Francisco Ribes Miriam Romero Pablo Roca Beatriz Sánchez-Capilla Antonio Sánchez-Borrego Rafael Santaballa Ana Santamaría Amparo Simoncini Tommaso Tinahones Francisco Calaf Joaquín Eligibility criteria for Menopausal Hormone Therapy (MHT): a position statement from a consortium of scientific societies for the use of MHT in women with medical conditions. MHT Eligibility Criteria Group Maturitas 2022 08 65 85 166 10.1016/j.maturitas.2022.08.008De Filippis Anna Ullah Hammad Baldi Alessandra Dacrema Marco Esposito Cristina Garzarella Emanuele Ugo Santarcangelo Cristina Tantipongpiradet Ariyawan Daglia Maria Gastrointestinal Disorders and Metabolic Syndrome: Dysbiosis as a Key Link and Common Bioactive Dietary Components Useful for their Treatment International Journal of Molecular Sciences 2020 07 4929 21 14 10.3390/ijms21144929Zuvarox T, Goosenberg E, Belletieri C. Malabsorption Syndromes. In: StatPearls-Treasure Island (FL): StatPearls Publishing; 2025. PMID: 31971746Elkafas Hoda Walls Melinique Al-Hendy Ayman Ismail Nahed Gut and genital tract microbiomes: Dysbiosis and link to gynecological disorders Frontiers in Cellular and Infection Microbiology 2022 12 12 10.3389/fcimb.2022.1059825Xie Xinyuan Song Jinbin Wu Yue Li Mei Guo Wenfeng Li Shuang Li Yanwu Study on gut microbiota and metabolomics in postmenopausal women BMC Women's Health 2024 11 24 1 10.1186/s12905-024-03448-7The 2022 hormone therapy position statement of The North American Menopause Society Menopause 2022 07 767 794 29 7 10.1097/gme.0000000000002028Kim Ji-Eun Chang Jae-Hyuck Jeong Min-Ji Choi Jaesung Park JooYong Baek Chaewon Shin Aesun Park Sang Min Kang Daehee Choi Ji-Yeob A systematic review and meta-analysis of effects of menopausal hormone therapy on cardiovascular diseases Scientific Reports 2020 11 10 1 10.1038/s41598-020-77534-9Boardman Henry MP Hartley Louise Eisinga Anne Main Caroline Roqué i Figuls Marta Bonfill Cosp Xavier Gabriel Sanchez Rafael Knight Beatrice Hormone therapy for preventing cardiovascular disease in post-menopausal women Cochrane Database of Systematic Reviews 2015 03 2015 8 10.1002/14651858.cd002229.pub4Vinogradova Yana Coupland Carol Hippisley-Cox Julia Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases BMJ 2019 01 k4810 10.1136/bmj.k4810Goldštajn Marina Šprem Mikuš Mislav Ferrari Filippo Alberto Bosco Mariachiara Uccella Stefano Noventa Marco Török Peter Terzic Sanja Laganà Antonio Simone Garzon Simone Effects of transdermal versus oral hormone replacement therapy in postmenopause: a systematic review Archives of Gynecology and Obstetrics 2022 06 1727 1745 307 6 10.1007/s00404-022-06647-5Kapoor Ekta Kling Juliana M. Lobo Angie S. Faubion Stephanie S. Menopausal hormone therapy in women with medical conditions Best Practice & Research Clinical Endocrinology & Metabolism 2021 09 101578 35 6 10.1016/j.beem.2021.101578Morris Guy Talaulikar Vikram Hormone replacement therapy in women with history of thrombosis or a thrombophilia Post Reproductive Health 2022 12 33 41 29 1 10.1177/20533691221148036Dinger J. Bardenheuer K. Heinemann K. Drospirenone plus estradiol and the risk of serious cardiovascular events in postmenopausal women Climacteric 2016 05 349 356 19 4 10.1080/13697137.2016.1183624Sobel Talia H. Shen Wen Transdermal estrogen therapy in menopausal women at increased risk for thrombotic events: a scoping review Menopause 2022 01 483 490 29 4 10.1097/gme.0000000000001938Roetker Nicholas MacLehose Richard Hoogeveen Ron Ballantyne Christie Basu Saonli Cushman Mary Folsom Aaron Prospective Study of Endogenous Hormones and Incidence of Venous Thromboembolism: The Atherosclerosis Risk in Communities Study Thrombosis and Haemostasis 2018 10 1940 1950 118 11 10.1055/s-0038-1673613Tepper Naomi K. Whiteman Maura K. Marchbanks Polly A. James Andra H. Curtis Kathryn M. Progestin-only contraception and thromboembolism: A systematic review Contraception 2016 05 678 700 94 6 10.1016/j.contraception.2016.04.014Mantha S. Karp R. Raghavan V. Terrin N. Bauer K. A. Zwicker J. I. Assessing the risk of venous thromboembolic events in women taking progestin-only contraception: a meta-analysis BMJ 2012 08 e4944 e4944 345 aug07 2 10.1136/bmj.e4944Nudy Matthew Chinchilli Vernon M. Foy Andrew J. A systematic review and meta-regression analysis to examine the ‘timing hypothesis’ of hormone replacement therapy on mortality, coronary heart disease, and stroke IJC Heart & Vasculature 2019 01 123 131 22 10.1016/j.ijcha.2019.01.001Cho Leslie Kaunitz Andrew M. Faubion Stephanie S. Hayes Sharonne N. Lau Emily S. Pristera Nicole Scott Nandita Shifren Jan L. Shufelt Chrisandra L. Stuenkel Cynthia A. Lindley Kathryn J. Rethinking Menopausal Hormone Therapy: For Whom, What, When, and How Long? Circulation 2023 02 597 610 147 7 10.1161/circulationaha.122.061559LaVasseur Corinne Neukam Suvi Kartika Thomas Samuelson Bannow Bethany Shatzel Joseph DeLoughery Thomas G. Hormonal therapies and venous thrombosis: Considerations for prevention and management Research and Practice in Thrombosis and Haemostasis 2022 08 e12763 6 6 10.1002/rth2.12763Roach Rachel E. J. Lijfering Willem M. van Hylckama Vlieg Astrid Helmerhorst Frans M. Rosendaal Frits R. Cannegieter Suzanne C. The risk of venous thrombosis in individuals with a history of superficial vein thrombosis and acquired venous thrombotic risk factors Blood 2013 11 4264 4269 122 26 10.1182/blood-2013-07-518159Straczek Céline Oger Emmanuel Yon de Jonage-Canonico Marianne Beau Plu-Bureau Geneviève Conard Jacqueline Meyer Guy Alhenc-Gelas Martine Lévesque Hervé Trillot Nathalie Barrellier Marie-Thérèse Wahl Denis Emmerich Joseph Scarabin Pierre-Yves Prothrombotic Mutations, Hormone Therapy, and Venous Thromboembolism Among Postmenopausal Women Circulation 2005 11 3495 3500 112 22 10.1161/circulationaha.105.565556Middeldorp Saskia Nieuwlaat Robby Baumann Kreuziger Lisa Coppens Michiel Houghton Damon James Andra H. Lang Eddy Moll Stephan Myers Tarra Bhatt Meha Chai-Adisaksopha Chatree Colunga-Lozano Luis E. Karam Samer G. Zhang Yuan Wiercioch Wojtek Schünemann Holger J. Iorio Alfonso American Society of Hematology 2023 guidelines for management of venous thromboembolism: thrombophilia testing Blood Advances 2023 05 7101 7138 7 22 10.1182/bloodadvances.2023010177Guyatt Gordon H. Akl Elie A. Crowther Mark Gutterman David D. Schuünemann Holger J. Executive Summary Chest 2012 02 7S 47S 141 2 10.1378/chest.1412s3Hulley Stephen Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women JAMA 2003 03 605 280 7 10.1001/jama.280.7.605Yuk Jin-Sung Kim Gwang Sil Kim Dong-Gil Byun Young Sup Kim Myoung-Hwan Yoon Sang-Hee Han Gwan Hee Kim Byung Gyu Association of menopausal hormone therapy with risk of cardiovascular disease in Korean women European Journal of Endocrinology 2025 02 73 80 192 2 10.1093/ejendo/lvae161Wassertheil-Smoller Sylvia Hendrix Susan Limacher Marian Heiss Gerardo Kooperberg Charles Baird Alison Kotchen Theodore Curb J. David Black Henry Rossouw Jacques E. Aragaki Aaron Safford Monika Stein Evan Laowattana Somchai Mysiw W. Jerry for the WHI Investigators Effect of Estrogen Plus Progestin on Stroke in Postmenopausal Women JAMA 2003 05 2673 289 20 10.1001/jama.289.20.2673Hendrix Susan L. Wassertheil-Smoller Sylvia Johnson Karen C. Howard Barbara V. Kooperberg Charles Rossouw Jacques E. Trevisan Maurizio Aragaki Aaron Baird Alison E. Bray Paul F. Buring Julie E. Criqui Michael H. Herrington David Lynch John K. Rapp Stephen R. Torner James Effects of Conjugated Equine Estrogen on Stroke in the Women’s Health Initiative Circulation 2006 05 2425 2434 113 20 10.1161/circulationaha.105.594077te West Nevine I. D. Day Ric O. Hiley Basia White Chris  Wright Mike Moore Kate H. Estriol serum levels in new and chronic users of vaginal estriol cream: A prospective observational study Neurourology and Urodynamics 2020 04 1137 1144 39 4 10.1002/nau.24331Santen Richard J. Mirkin Sebastian Bernick Brian Constantine Ginger D. Systemic estradiol levels with low-dose vaginal estrogens Menopause 2019 12 361 370 27 3 10.1097/gme.0000000000001463Bhupathiraju Shilpa N. Grodstein Francine Stampfer Meir J. Willett Walter C. Crandall Carolyn J. Shifren Jan L. Manson JoAnn E. Vaginal estrogen use and chronic disease risk in the Nurses’ Health Study Menopause 2018 12 603 610 26 6 10.1097/gme.0000000000001284Crandall Carolyn J. Hovey Kathleen M. Andrews Christopher A. Chlebowski Rowan T. Stefanick Marcia L. Lane Dorothy S. Shifren Jan Chen Chu Kaunitz Andrew M. Cauley Jane A. Manson JoAnn E. Breast cancer, endometrial cancer, and cardiovascular events in participants who used vaginal estrogen in the Women's Health Initiative Observational Study Menopause 2017 08 11 20 25 1 10.1097/gme.0000000000000956Orlova I.A. Plisyuk A.G. Dolgushin G.O. Kirillova K.I. Mikheev R.K. Andreeva E.N. Correlation between prolonged menopausal hormonotherapy and indicators of vascular and replicative aging in women Russian Journal of Preventive Medicine 2023 07 96 26 7 10.17116/profmed20232607196Draper Michael W. Flowers David E. Huster William J. Neild Julie A. Harper Kristine D. Arnaud Claude A controlled trial of raloxifene (LY139481) HCl: Impact on bone turnover and serum lipid profile in healthy postmenopausal women Journal of Bone and Mineral Research 2010 02 835 842 11 6 10.1002/jbmr.5650110615Nie Guangning Yang Xiaofei Wang Yangyang Liang Wanshi Li Xuewen Luo Qiyuan Yang Hongyan Liu Jian Wang Jiajing Guo Qinghua Yu Qi Liang Xuefang The Effects of Menopause Hormone Therapy on Lipid Profile in Postmenopausal Women: A Systematic Review and Meta-Analysis Frontiers in Pharmacology 2022 04 13 10.3389/fphar.2022.850815Ezhov M. V. Kukharchuk V. V. Sergienko I. V. Alieva A. S. Antsiferov M. B. Ansheles A. A. Arabidze G. G. Aronov D. M. Arutyunov G. P. Akhmedzhanov N. M. Balakhonova T. V. Barbarash O. L. Boytsov S. A. Bubnova M. G. Voevoda M. I. Galstyan G. R. Galyavich A. S. Gornyakova N. B. Gurevich V. S. Dedov I. I. Drapkina O. M. Duplyakov D. V. Eregin S. Ya. Ershova A. I. Irtyuga O. B. Karpov R. S. Karpov Yu. A. Kachkovsky M. A. Kobalava Zh. D. Koziolova N. A. Konovalov G. A. Konstantinov V. O. Kosmacheva E. D. Kotovskaya Yu. V. Martynov A. I. Meshkov A. N. Nebieridze D. V. Nedogoda S. V. Obrezan A. G. Oleinikov V. E. Pokrovsky S. N. Ragino Yu. I. Rotar O. P. Skibitsky V. V. Smolenskaya O. G. Sokolov A. A. Sumarokov A. B. Filippov E. Halimov Yu. Sh. Chazova I. E. Shaposhnik I. I. Shestakova M. V. Yakushin S. S. Shlyakhto E. V. Disorders of lipid metabolism. Clinical Guidelines 2023 Russian Journal of Cardiology 2023 06 5471 28 5 10.15829/1560-4071-2023-5471Nordestgaard Børge G. Chapman M. John Ray Kausik Borén Jan Andreotti Felicita Watts Gerald F. Ginsberg Henry Amarenco Pierre Catapano Alberico Descamps Olivier S. Fisher Edward Kovanen Petri T. Kuivenhoven Jan Albert Lesnik Philippe Masana Luis Reiner Zeljko Taskinen Marja-Riitta Tokgözoglu Lale Tybjærg-Hansen Anne Lipoprotein(a) as a cardiovascular risk factor: current status European Heart Journal 2010 10 2844 2853 31 23 10.1093/eurheartj/ehq386Honigberg Michael C. Trinder Mark Natarajan Pradeep Lipoprotein(a), Menopausal Hormone Therapy, and Risk of Coronary Heart Disease in Postmenopausal Individuals JAMA Cardiology 2022 04 565 7 5 10.1001/jamacardio.2022.0716Stevenson John C. Chines Arkadi Pan Kaijie Ryan Kelly A. Mirkin Sebastian A Pooled Analysis of the Effects of Conjugated Estrogens/Bazedoxifene on Lipid Parameters in Postmenopausal Women From the Selective Estrogens, Menopause, and Response to Therapy (SMART) Trials The Journal of Clinical Endocrinology & Metabolism 2015 04 2329 2338 100 6 10.1210/jc.2014-2649Miller Valery T. Effects of Estrogen or Estrogen/ Progestin Regimens on Heart Disease Risk Factors in Postmenopausal Women JAMA 2011 12 199 273 3 10.1001/jama.1995.03520270033028Binder Ellen F. Birge Stanley J. Kohrt Wendy M. Effects of Endurance Exercise and Hormone Replacement Therapy on Serum Lipids in Older Women Journal of the American Geriatrics Society 2015 04 231 236 44 3 10.1111/j.1532-5415.1996.tb00907.xBunyavejchevin S, Limpaphayom KK. The metabolic and bone density effects of continuous combined 17-beta estradiol and noresthisterone acetate treatments in Thai postmenopausal women: a doubleblind placebo-controlled trial. Journal of the Medical Association of Thailand. 2001;84(1):45–53. PMID: 11281499Çayan F, Gen R, Akbay E, Dilek U, Dilek S. The Effect of Hormone Therapy and Tibolone on Glucose and Lipid Metabolism in Healthy Postmenopausal Women. Turkish Journal of Geriatrics. 2011;14(1):19– 25. [Av. at: https://geriatri.dergisi.org/abstract.php?id=534]Cheng GJ, Liu JL, Zhang Q, Fan W, Ye HF, Wang ZQ et al. Nylestriol replacement therapy in postmenopausal women. A three-year prospective study. Chinese Medical Journal. 1993;106(12):911–6. PMID: 8198628Conard Jacqueline Basdevant Arnaud Thomas Jean-Louis Ochsenbein Edith Denis Catherine Guyene Than Tam Degrelle Hervé Cardiovascular risk factors and combined estrogen-progestin replacement therapy: a placebo-controlled study with nomegestrol acetate and estradiol Fertility and Sterility 2016 04 957 962 64 5 10.1016/s0015-0282(16)57909-6Conard Jacqueline Gompel Anne Pelissier Clara Mirabel Catherine Basdevant Arnaud Fibrinogen and plasminogen modifications during oral estradiol replacement therapy Fertility and Sterility 2002 07 449 453 68 3 10.1016/s0015-0282(97)00220-3Davidson Michael H. Maki Kevin C. Marx Phyllis Maki Ann C. Cyrowski Mary Sue Nanavati Nayan Arce Joan-Carles Effects of Continuous Estrogen and Estrogen-Progestin Replacement Regimens on Cardiovascular Risk Markers in Postmenopausal Women Archives of Internal Medicine 2003 03 3315 160 21 10.1001/archinte.160.21.3315Duvernoy Claire S. Rose Patricia A. Kim H. Myra Kehrer Christine Brook Robert D. Combined Continuous Ethinyl Estradiol/Norethindrone Acetate Does Not Improve Forearm Blood Flow in Postmenopausal Women at Risk for Cardiovascular Events: A Pilot Study Journal of Women's Health 2007 09 963 970 16 7 10.1089/jwh.2006.0321Casanova G. dos Reis A. M. Spritzer P. M. Low-dose oral or non-oral hormone therapy: effects on C-reactive protein and atrial natriuretic peptide in menopause Climacteric 2014 09 86 93 18 1 10.3109/13697137.2014.940309Haase Christiane L. Tybjærg-Hansen Anne Ali Qayyum Abbas Schou Jesper Nordestgaard Børge G. Frikke-Schmidt Ruth LCAT, HDL Cholesterol and Ischemic Cardiovascular Disease: A Mendelian Randomization Study of HDL Cholesterol in 54,500 Individuals The Journal of Clinical Endocrinology & Metabolism 2011 11 E248 E256 97 2 10.1210/jc.2011-1846Lv Changyu Zhang Wencui Tan Xia Shang Xianping Găman Mihnea-Alexandru Salem Hany Abu-Zaid Ahmed Wang Xiaohong The effect of tibolone treatment on lipid profile in women: A systematic review and dose-response meta-analysis of randomized controlled trials Pharmacological Research 2021 04 105612 169 10.1016/j.phrs.2021.105612Anagnostis Panagiotis Galanis Petros Chatzistergiou Vasileia Stevenson John C. Godsland Ian F. Lambrinoudaki Irene Theodorou Mamas Goulis Dimitrios G. The effect of hormone replacement therapy and tibolone on lipoprotein (a) concentrations in postmenopausal women: A systematic review and meta-analysis Maturitas 2017 02 27 36 99 10.1016/j.maturitas.2017.02.009FALKEBORN MARGARETA PERSSON INGEMAR ADAMI HANS‐OLOV BERGSTRÖM REINHOLD EAKER ELAINE LITHELL HANS MOHSEN RAWYA NAESSEN TORD The risk of acute myocardial infarction after oestrogen and oestrogen‐progestogen replacement BJOG: An International Journal of Obstetrics & Gynaecology 2005 08 821 828 99 10 10.1111/j.1471-0528.1992.tb14414.xShufelt Chrisandra L Manson JoAnn E Menopausal Hormone Therapy and Cardiovascular Disease: The Role of Formulation, Dose, and Route of Delivery The Journal of Clinical Endocrinology & Metabolism 2021 01 1245 1254 106 5 10.1210/clinem/dgab042Anagnostis Panagiotis Bitzer Johannes Cano Antonio Ceausu Iuliana Chedraui Peter Durmusoglu Fatih Erkkola Risto Goulis Dimitrios G. Hirschberg Angelica Lindén Kiesel Ludwig Lopes Patrice Pines Amos van Trotsenburg Mick Lambrinoudaki Irene Rees Margaret Menopause symptom management in women with dyslipidemias: An EMAS clinical guide Maturitas 2020 03 82 88 135 10.1016/j.maturitas.2020.03.007Wenger Nanette K. Lloyd-Jones Donald M. Elkind Mitchell S.V. Fonarow Gregg C. Warner John J. Alger Heather M. Cheng Susan Kinzy Claire Hall Jennifer L. Roger Véronique L. Call to Action for Cardiovascular Disease in Women: Epidemiology, Awareness, Access, and Delivery of Equitable Health Care: A Presidential Advisory From the American Heart Association Circulation 2022 05 145 23 10.1161/cir.0000000000001071Vogel Birgit Acevedo Monica Appelman Yolande Bairey Merz C Noel Chieffo Alaide Figtree Gemma A Guerrero Mayra Kunadian Vijay Lam Carolyn S P Maas Angela H E M Mihailidou Anastasia S Olszanecka Agnieszka Poole Jeanne E Saldarriaga Clara Saw Jacqueline Zühlke Liesl Mehran Roxana The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030 The Lancet 2021 05 2385 2438 397 10292 10.1016/s0140-6736(21)00684-xReckelhoff Jane F. Gender differences in hypertension Current Opinion in Nephrology and Hypertension 2018 02 176 181 27 3 10.1097/mnh.0000000000000404Cho Leslie Davis Melinda Elgendy Islam Epps Kelly Lindley Kathryn J. Mehta Puja K. Michos Erin D. Minissian Margo Pepine Carl Vaccarino Viola Volgman Annabelle Santos Summary of Updated Recommendations for Primary Prevention of Cardiovascular Disease in Women Journal of the American College of Cardiology 2020 05 2602 2618 75 20 10.1016/j.jacc.2020.03.060Gerdts Eva Sudano Isabella Brouwers Sofie Borghi Claudio Bruno Rosa Maria Ceconi Claudio Cornelissen Véronique Diévart François Ferrini Marc Kahan Thomas Løchen Maja-Lisa Maas Angela H E M Mahfoud Felix Mihailidou Anastasia S Moholdt Trine Parati Gianfranco de Simone Giovanni Sex differences in arterial hypertension European Heart Journal 2022 09 4777 4788 43 46 10.1093/eurheartj/ehac470Zhou Bin Carrillo-Larco Rodrigo M Danaei Goodarz Riley Leanne M Paciorek Christopher J Stevens Gretchen A Gregg Edward W Bennett James E Solomon Bethlehem Singleton Rosie K Sophiea Marisa K Iurilli Maria LC Lhoste Victor PF Cowan Melanie J Savin Stefan Woodward Mark Balanova Yulia Cifkova Renata Damasceno Albertino Elliott Paul Farzadfar Farshad He Jiang Ikeda Nayu Kengne Andre P Khang Young-Ho Kim Hyeon Chang Laxmaiah Avula Lin Hsien-Ho Margozzini Maira Paula Miranda J Jaime Neuhauser Hannelore Sundström Johan Varghese Cherian Widyahening Indah S Zdrojewski Tomasz Abarca-Gómez Leandra Abdeen Ziad A Abdul Rahim Hanan F Abu-Rmeileh Niveen M Acosta-Cazares Benjamin Adams Robert J Aekplakorn Wichai Afsana Kaosar Afzal Shoaib Agdeppa Imelda A Aghazadeh-Attari Javad Aguilar-Salinas Carlos A Agyemang Charles Ahmad Noor Ani Ahmadi Ali Ahmadi Naser Ahmadi Nastaran Ahmadizar Fariba Ahmed Soheir H Ahrens Wolfgang Ajlouni Kamel Al-Raddadi Rajaa Alarouj Monira AlBuhairan Fadia AlDhukair Shahla Ali Mohamed M Alkandari Abdullah Alkerwi Ala'a Allin Kristine Aly Eman Amarapurkar Deepak N Amougou Norbert Amouyel Philippe Andersen Lars Bo Anderssen Sigmund A Anjana Ranjit Mohan Ansari-Moghaddam Alireza Ansong Daniel Aounallah-Skhiri Hajer Araújo Joana Ariansen Inger Aris Tahir Arku Raphael E Arlappa Nimmathota Aryal Krishna K Aspelund Thor Assah Felix K Assunção Maria Cecília F Auvinen Juha Avdićová Mária Azevedo Ana Azimi-Nezhad Mohsen Azizi Fereidoun Azmin Mehrdad Babu Bontha V Bahijri Suhad Balakrishna Nagalla Bamoshmoosh Mohamed Banach Maciej Banadinović Maja Bandosz Piotr Banegas José R Baran Joanna Barbagallo Carlo M Barceló Alberto Barkat Amina Barreto Marta Barros Aluisio JD Barros Mauro Virgílio Gomes Bartosiewicz Anna Basit Abdul Bastos Joao Luiz D Bata Iqbal Batieha Anwar M Batyrbek Assembekov Baur Louise A Beaglehole Robert Belavendra Antonisamy Ben Romdhane Habiba Benet Mikhail Benson Lowell S Berkinbayev Salim Bernabe-Ortiz Antonio Bernotiene Gailute Bettiol Heloísa Bezerra Jorge Bhagyalaxmi Aroor Bhargava Santosh K Bia Daniel Biasch Katia Bika Lele Elysée Claude Bikbov Mukharram M Bista Bihungum Bjerregaard Peter Bjertness Espen Bjertness Marius B Björkelund Cecilia Bloch Katia V Blokstra Anneke Bo Simona Bobak Martin Boeing Heiner Boggia Jose G Boissonnet Carlos P Bojesen Stig E Bongard Vanina Bonilla-Vargas Alice Bopp Matthias Borghs Herman Bovet Pascal Boyer Christopher B Braeckman Lutgart Brajkovich Imperia Branca Francesco Breckenkamp Juergen Brenner Hermann Brewster Lizzy M Briceño Yajaira Brito Miguel Bruno Graziella Bueno-de-Mesquita H Bas Bueno Gloria Bugge Anna Burns Con Bursztyn Michael Cabrera de León Antonio Cacciottolo Joseph Cameron Christine Can Günay Cândido Ana Paula C Capanzana Mario V Čapková Naděžda Capuano Eduardo Capuano Vincenzo Cardoso Viviane C Carlsson Axel C Carvalho Joana Casanueva Felipe F Censi Laura Cervantes-Loaiza Marvin Chadjigeorgiou Charalambos A Chamukuttan Snehalatha Chan Angelique W Chan Queenie Chaturvedi Himanshu K Chaturvedi Nish Chee Miao Li Chen Chien-Jen Chen Fangfang Chen Huashuai Chen Shuohua Chen Zhengming Cheng Ching-Yu Cheraghian Bahman Cherkaoui Dekkaki Imane Chetrit Angela Chien Kuo-Liong Chiolero Arnaud Chiou Shu-Ti Chirita-Emandi Adela Chirlaque María-Dolores Cho Belong Christensen Kaare Christofaro Diego G Chudek Jerzy Cinteza Eliza Claessens Frank Clarke Janine Clays Els Cohen Emmanuel Concin Hans Cooper Cyrus Coppinger Tara C Costanzo Simona Cottel Dominique Cowell Chris Craig Cora L Crampin Amelia C Crujeiras Ana B Cruz Juan J Csilla Semánová Cui Liufu Cureau Felipe V Cuschieri Sarah D'Arrigo Graziella d'Orsi Eleonora Dallongeville Jean Dankner Rachel Dantoft Thomas M Dauchet Luc Davletov Kairat De Backer Guy De Bacquer Dirk De Curtis Amalia de Gaetano Giovanni De Henauw Stefaan de Oliveira Paula Duarte De Ridder David De Smedt Delphine Deepa Mohan Deev Alexander D DeGennaro Vincent Jr Delisle Hélène Demarest Stefaan Dennison Elaine Deschamps Valérie Dhimal Meghnath Di Castelnuovo Augusto F Dias-da-Costa Juvenal Soares Diaz Alejandro Dickerson Ty T Dika Zivka Djalalinia Shirin Do Ha TP Dobson Annette J Donfrancesco Chiara Donoso Silvana P Döring Angela Dorobantu Maria Dörr Marcus Doua Kouamelan Dragano Nico Drygas Wojciech Duante Charmaine A Duboz Priscilla Duda Rosemary B Dulskiene Virginija Dushpanova Anar Džakula Aleksandar Dzerve Vilnis Dziankowska-Zaborszczyk Elzbieta Eddie Ricky Eftekhar Ebrahim Eggertsen Robert Eghtesad Sareh Eiben Gabriele Ekelund Ulf El-Khateeb Mohammad El Ati Jalila Eldemire-Shearer Denise Eliasen Marie Elosua Roberto Erasmus Rajiv T Erbel Raimund Erem Cihangir Eriksen Louise Eriksson Johan G Escobedo-de la Peña Jorge Eslami Saeid Esmaeili Ali Evans Alun Faeh David Fakhretdinova Albina A Fall Caroline H Faramarzi Elnaz Farjam Mojtaba Fattahi Mohammad Reza Fawwad Asher Felix-Redondo Francisco J Felix Stephan B Ferguson Trevor S Fernandes Romulo A Fernández-Bergés Daniel Ferrante Daniel Ferrao Thomas Ferrari Marika Ferrario Marco M Ferreccio Catterina Ferreira Haroldo S Ferrer Eldridge Ferrieres Jean Figueiró Thamara Hubler Fink Günther Fischer Krista Foo Leng Huat Forsner Maria Fouad Heba M Francis Damian K Franco Maria do Carmo Frikke-Schmidt Ruth Frontera Guillermo Fuchs Flavio D Fuchs Sandra C Fujita Yuki Fumihiko Matsuda Furdela Viktoriya Furer Ariel Furusawa Takuro Gaciong Zbigniew Galbarczyk Andrzej Galenkamp Henrike Galvano Fabio Gao Jingli Gao Pei Garcia-de-la-Hera Manoli Garcia Pablo Gareta Dickman Garnett Sarah P Gaspoz Jean-Michel Gasull Magda Gazzinelli Andrea Gehring Ulrike Geleijnse Johanna M George Ronnie Ghanbari Ali Ghasemi Erfan Gheorghe-Fronea Oana-Florentina Ghimire Anup Gialluisi Alessandro Giampaoli Simona Gieger Christian Gill Tiffany K Giovannelli Jonathan Gironella Glen Giwercman Aleksander Gkiouras Konstantinos Goldberg Marcel Goldsmith Rebecca A Gomez Luis F Gomula Aleksandra Gonçalves Helen Gonçalves Mauer Gonçalves Cordeiro da Silva Bruna Gonzalez-Chica David A Gonzalez-Gross Marcela González-Rivas Juan P González-Villalpando Clicerio González-Villalpando María-Elena Gonzalez Angel R Gorbea Mariano Bonet Gottrand Frederic Graff-Iversen Sidsel Grafnetter Dušan Grajda Aneta Grammatikopoulou Maria G Gregor Ronald D Grodzicki Tomasz Grosso Giuseppe Gruden Gabriella Gu Dongfeng Guan Ong Peng Gudmundsson Elias F Gudnason Vilmundur Guerrero Ramiro Guessous Idris Guimaraes Andre L Gulliford Martin C Gunnlaugsdottir Johanna Gunter Marc J Gupta Prakash C Gupta Rajeev Gureje Oye Gurzkowska Beata Gutierrez Laura Gutzwiller Felix Ha Seongjun Hadaegh Farzad Haghshenas Rosa Hakimi Hamid Halkjær Jytte Hambleton Ian R Hamzeh Behrooz Hange Dominique Hanif Abu AM Hantunen Sari Hao Jie Hardman Carla Menêses Hari Kumar Rachakulla Hashemi-Shahri Seyed Mohammad Hata Jun Haugsgjerd Teresa Hayes Alison J He Yuna Heier Margit Hendriks Marleen Elisabeth Henrique Rafael dos Santos Henriques Ana Hernandez Cadena Leticia Herqutanto Herrala Sauli Heshmat Ramin Hill Allan G Ho Sai Yin Ho Suzanne C Hobbs Michael Holdsworth Michelle Homayounfar Reza Horasan Dinc Gonul Horimoto Andrea RVR Hormiga Claudia M Horta Bernardo L Houti Leila Howitt Christina Htay Thein Thein Htet Aung Soe Htike Maung Maung Than Hu Yonghua Huerta José María Huhtaniemi Ilpo Tapani Huiart Laetitia Huisman Martijn Husseini Abdullatif S Huybrechts Inge Hwalla Nahla Iacoviello Licia Iannone Anna G Ibrahim Mohsen M Ibrahim Wong Norazizah Ikram M Arfan Iotova Violeta Irazola Vilma E Ishida Takafumi Isiguzo Godsent C Islam Muhammad Islam Sheikh Mohammed Shariful Iwasaki Masanori Jackson Rod T Jacobs Jeremy M Jaddou Hashem Y Jafar Tazeen James Kenneth Jamrozik Konrad Janszky Imre Janus Edward Jarvelin Marjo-Riitta Jasienska Grazyna Jelaković Ana Jelaković Bojan Jennings Garry Jha Anjani Kumar Jiang Chao Qiang Jimenez Ramon O Jöckel Karl-Heinz Joffres Michel Johansson Mattias Jokelainen Jari J Jonas Jost B Jørgensen Torben Joshi Pradeep Joukar Farahnaz Jóżwiak Jacek Juolevi Anne Jurak Gregor Jureša Vesna Kaaks Rudolf Kafatos Anthony Kajantie Eero O Kalmatayeva Zhanna Kalpourtzi Natasa Kalter-Leibovici Ofra Kampmann Freja B Kannan Srinivasan Karaglani Eva Kårhus Line L Karki Khem B Katibeh Marzieh Katz Joanne Kauhanen Jussi Kaur Prabhdeep Kavousi Maryam Kazakbaeva Gyulli M Keil Ulrich Keinan Boker Lital Keinänen-Kiukaanniemi Sirkka Kelishadi Roya Kemper Han CG Keramati Maryam Kerimkulova Alina Kersting Mathilde Key Timothy Khader Yousef Saleh Khalili Davood Khaw Kay-Tee Kheiri Bahareh Kheradmand Motahareh Khosravi Alireza Kiechl-Kohlendorfer Ursula Kiechl Stefan Killewo Japhet Kim Dong Wook Kim Jeongseon Klakk Heidi Klimek Magdalena Klumbiene Jurate Knoflach Michael Kolle Elin Kolsteren Patrick Kontto Jukka P Korpelainen Raija Korrovits Paul Kos Jelena Koskinen Seppo Kouda Katsuyasu Kowlessur Sudhir Koziel Slawomir Kratenova Jana Kriaucioniene Vilma Kristensen Peter Lund Krokstad Steiner Kromhout Daan Kruger Herculina S Kubinova Ruzena Kuciene Renata Kujala Urho M Kulaga Zbigniew Kumar R Krishna Kurjata Pawel Kusuma Yadlapalli S Kutsenko Vladimir Kuulasmaa Kari Kyobutungi Catherine Laatikainen Tiina Lachat Carl Laid Youcef Lam Tai Hing Landrove Orlando Lanska Vera Lappas Georg Larijani Bagher Latt Tint Swe Le Coroller Gwenaëlle Le Nguyen Bao Khanh Le Tuyen D Lee Jeannette Lee Jeonghee Lehmann Nils Lehtimäki Terho Lemogoum Daniel Levitt Naomi S Li Yanping Lilly Christa L Lim Wei-Yen Lima-Costa M Fernanda Lin Xu Lin Yi-Ting Lind Lars Lingam Vijaya Linneberg Allan Lissner Lauren Litwin Mieczyslaw Lo Wei-Cheng Loit Helle-Mai Lopez-Garcia Esther Lopez Tania Lotufo Paulo A Lozano José Eugenio Lukačević Lovrenčić Iva Lukrafka Janice L Luksiene Dalia Lundqvist Annamari Lundqvist Robert Lunet Nuno Lustigová Michala Luszczki Edyta Ma Guansheng Ma Jun Machado-Coelho George LL Machado-Rodrigues Aristides M Macia Enguerran Macieira Luisa M Madar Ahmed A Maggi Stefania Magliano Dianna J Magriplis Emmanuella Mahasampath Gowri Maire Bernard Majer Marjeta Makdisse Marcia Malekzadeh Fatemeh Malekzadeh Reza Malhotra Rahul Mallikharjuna Rao Kodavanti Malyutina Sofia K Maniego Lynell V Manios Yannis Mann Jim I Mansour-Ghanaei Fariborz Manzato Enzo Marcil Anie Mårild Staffan B Marinović Glavić Mihalea Marques-Vidal Pedro Marques Larissa Pruner Marrugat Jaume Martorell Reynaldo Mascarenhas Luis P Matasin Marija Mathiesen Ellisiv B Mathur Prashant Matijasevich Alicia Matlosz Piotr Matsha Tandi E Mavrogianni Christina Mbanya Jean Claude N Mc Donald Posso Anselmo J McFarlane Shelly R McGarvey Stephen T McLachlan Stela McLean Rachael M McLean Scott B McNulty Breige A Mediene Benchekor Sounnia Medzioniene Jurate Mehdipour Parinaz Mehlig Kirsten Mehrparvar Amir Houshang Meirhaeghe Aline Meisinger Christa Mendoza Montano Carlos Menezes Ana Maria B Menon Geetha R Mereke Alibek Meshram Indrapal I Metspalu Andres Meyer Haakon E Mi Jie Michels Nathalie Mikkel Kairit Milkowska Karolina Miller Jody C Minderico Cláudia S Mini GK Mirjalili Mohammad Reza Mirrakhimov Erkin Mišigoj-Duraković Marjeta Modesti Pietro A Moghaddam Sahar Saeedi Mohajer Bahram Mohamed Mostafa K Mohamed Shukri F Mohammad Kazem Mohammadi Mohammad Reza Mohammadi Zahra Mohammadifard Noushin Mohammadpourhodki Reza Mohan Viswanathan Mohanna Salim Mohd Yusoff Muhammad Fadhli Mohebbi Iraj Mohebi Farnam Moitry Marie Møllehave Line T Molnár Dénes Momenan Amirabbas Mondo Charles K Monterrubio-Flores Eric Monyeki Kotsedi Daniel K Moon Jin Soo Moosazadeh Mahmood Moreira Leila B Morejon Alain Moreno Luis A Morgan Karen Moschonis George Mossakowska Malgorzata Mostafa Aya Mostafavi Seyed-Ali Mota Jorge Motlagh Mohammad Esmaeel Motta Jorge Moura-dos-Santos Marcos André Mridha Malay K Msyamboza Kelias P Mu Thet Thet Muhihi Alfa J Muiesan Maria L Müller-Nurasyid Martina Murphy Neil Mursu Jaakko Musa Kamarul Imran Musić Milanović Sanja Musil Vera Mustafa Norlaila Nabipour Iraj Naderimagham Shohreh Nagel Gabriele Naidu Balkish M Najafi Farid Nakamura Harunobu Námešná Jana Nang Ei Ei K Nangia Vinay B Narake Sameer Ndiaye Ndeye Coumba Neal William A Nejatizadeh Azim Nenko Ilona Neovius Martin Nguyen Chung T Nguyen Nguyen D Nguyen Quang V Nguyen Quang Ngoc Nieto-Martínez Ramfis E Niiranen Teemu J Nikitin Yury P Ninomiya Toshiharu Nishtar Sania Njelekela Marina A Noale Marianna Noboa Oscar A Noorbala Ahmad Ali Norat Teresa Nordendahl Maria Nordestgaard Børge G Noto Davide Nowak-Szczepanska Natalia Nsour Mohannad Al Nunes Baltazar O'Neill Terence W O'Reilly Dermot Ochimana Caleb Oda Eiji Odili Augustine N Oh Kyungwon Ohara Kumiko Ohtsuka Ryutaro Olié Valérie Olinto Maria Teresa A Oliveira Isabel O Omar Mohd Azahadi Onat Altan Ong Sok King Ono Lariane M Ordunez Pedro Ornelas Rui Ortiz Pedro J Osmond Clive Ostojic Sergej M Ostovar Afshin Otero Johanna A Overvad Kim Owusu-Dabo Ellis Paccaud Fred Michel Padez Cristina Pahomova Elena Paiva Karina Mary de Pająk Andrzej Palli Domenico Palmieri Luigi Pan Wen-Harn Panda-Jonas Songhomitra Panza Francesco Paoli Mariela Papandreou Dimitrios Park Soon-Woo Park Suyeon Parnell Winsome R Parsaeian Mahboubeh Pasquet Patrick Patel Nikhil D Pavlyshyn Halyna Pećin Ivan Pednekar Mangesh S Pedro João M Peer Nasheeta Peixoto Sergio Viana Peltonen Markku Pereira Alexandre C Peres Karen GDA Peres Marco A Peters Annette Petkeviciene Janina Peykari Niloofar Pham Son Thai Pichardo Rafael N Pigeot Iris Pikhart Hynek Pilav Aida Pilotto Lorenza Pitakaka Freda Piwonska Aleksandra Pizarro Andreia n Plans-Rubió Pedro Polašek Ozren Porta Miquel Poudyal Anil Pourfarzi Farhad Pourshams Akram Poustchi Hossein Pradeepa Rajendra Price Alison J Price Jacqueline F Providencia Rui Puhakka Soile E Puiu Maria Punab Margus Qasrawi Radwan F Qorbani Mostafa Queiroz Daniel Quoc Bao Tran Radić Ivana Radisauskas Ricardas Rahimikazerooni Salar Rahman Mahfuzar Raitakari Olli Raj Manu Rakhimova Ellina M Ramachandra Rao Sudha Ramachandran Ambady Ramos Elisabete Rampal Lekhraj Rampal Sanjay Rangel Reina Daniel A Rarra Vayia Rech Cassiano Ricardo Redon Josep Reganit Paul Ferdinand M Regecová Valéria Revilla Luis Rezaianzadeh Abbas Ribeiro Robespierre Riboli Elio Richter Adrian Rigo Fernando Rinke de Wit Tobias F Ritti-Dias Raphael M Robitaille Cynthia Rodríguez-Artalejo Fernando Rodriguez-Perez María del Cristo Rodríguez-Villamizar Laura A Roggenbuck Ulla Rojas-Martinez Rosalba Romaguera Dora Romeo Elisabetta L Rosengren Annika Roy Joel GR Rubinstein Adolfo Ruidavets Jean-Bernard Ruiz-Betancourt Blanca Sandra Ruiz-Castell Maria Rusakova Iuliia A Russo Paola Rutkowski Marcin Sabanayagam Charumathi Sabbaghi Hamideh Sachdev Harshpal S Sadjadi Alireza Safarpour Ali Reza Safi Sare Safiri Saeid Saidi Olfa Sakarya Sibel Saki Nader Salanave Benoit Salazar Martinez Eduardo Salmerón Diego Salomaa Veikko Salonen Jukka T Salvetti Massimo Sánchez-Abanto Jose Sans Susana Santos Diana A Santos Ina S Santos Lèlita C Santos Maria Paula Santos Rute Saramies Jouko L Sardinha Luis B Sarganas Giselle Sarrafzadegan Nizal Sathish Thirunavukkarasu Saum Kai-Uwe Savva Savvas Sawada Norie Sbaraini Mariana Scazufca Marcia Schaan Beatriz D Schargrodsky Herman Schipf Sabine Schmidt Carsten O Schnohr Peter Schöttker Ben Schramm Sara Schultsz Constance Schutte Aletta E Sebert Sylvain Sein Aye Aye Sen Abhijit Senbanjo Idowu O Sepanlou Sadaf G Servais Jennifer Shalnova Svetlana A Shamah-Levy Teresa Shamshirgaran Morteza Shanthirani Coimbatore Subramaniam Sharafkhah Maryam Sharma Sanjib K Shaw Jonathan E Shayanrad Amaneh Shayesteh Ali Akbar Shi Zumin Shibuya Kenji Shimizu-Furusawa Hana Shin Dong Wook Shirani Majid Shiri Rahman Shrestha Namuna Si-Ramlee Khairil Siani Alfonso Siantar Rosalynn Sibai Abla M Silva Caroline Ramos de Moura Silva Diego Augusto Santos Simon Mary Simons Judith Simons Leon A Sjöström Michael Slowikowska-Hilczer Jolanta Slusarczyk Przemyslaw Smeeth Liam So Hung-Kwan Soares Fernanda Cunha Sobngwi Eugène Söderberg Stefan Soemantri Agustinus Sofat Reecha Solfrizzi Vincenzo Somi Mohammad Hossein Sonestedt Emily Song Yi Sørensen Thorkild IA Sørgjerd Elin P Sorić Maroje Sossa Jérome Charles Soumaré Aïcha Sparboe-Nilsen Bente Sparrenberger Karen Staessen Jan A Starc Gregor Stavreski Bill Steene-Johannessen Jostein Stehle Peter Stein Aryeh D Stergiou George S Stessman Jochanan Stieber Jutta Stöckl Doris Stocks Tanja Stokwiszewski Jakub Stronks Karien Strufaldi Maria Wany Suka Machi Sun Chien-An Sung Yn-Tz Suriyawongpaisal Paibul Sy Rody G Syddall Holly E Sylva René Charles Szklo Moyses Tai E Shyong Tammesoo Mari-Liis Tamosiunas Abdonas Tan Eng Joo Tang Xun Tanser Frank Tao Yong Tarawneh Mohammed Rasoul Tarqui-Mamani Carolina B Taylor Anne Taylor Julie Tebar William R Tell Grethe S Tello Tania Tham Yih Chung Thankappan KR Theobald Holger Theodoridis Xenophon Thijs Lutgarde Thinggaard Mikael Thomas Nihal Thorand Barbara Thuesen Betina H Timmermans Erik J Tjandrarini Dwi H Tjonneland Anne Toft Ulla Tolonen Hanna K Tolstrup Janne S Topbas Murat Topór-Madry Roman Tormo María José Tornaritis Michael J Torrent Maties Torres-Collado Laura Touloumi Giota Traissac Pierre Triantafyllou Areti Trichopoulos Dimitrios Trichopoulou Antonia Trinh Oanh TH Trivedi Atul Tshepo Lechaba Tsugane Shoichiro Tuliakova Azaliia M Tulloch-Reid Marshall K Tullu Fikru Tuomainen Tomi-Pekka Tuomilehto Jaakko Turley Maria L Twig Gilad Tynelius Per Tzourio Christophe Ueda Peter Ugel Eunice Ulmer Hanno Uusitalo Hannu MT Valdivia Gonzalo Valvi Damaskini van Dam Rob M van den Born Bert-Jan Van der Heyden Johan van der Schouw Yvonne T Van Herck Koen Van Minh Hoang Van Schoor Natasja M van Valkengoed Irene GM van Zutphen Elisabeth M Vanderschueren Dirk Vanuzzo Diego Varbo Anette Vasan Senthil K Vega Tomas Veidebaum Toomas Velasquez-Melendez Gustavo Veronesi Giovanni Verschuren WM Monique Verstraeten Roosmarijn Victora Cesar G Viet Lucie Villalpando Salvador Vineis Paolo Vioque Jesus Virtanen Jyrki K Visvikis-Siest Sophie Viswanathan Bharathi Vlasoff Tiina Vollenweider Peter Voutilainen Ari Wade Alisha N Walton Janette Wambiya Elvis OA Wan Bebakar Wan Mohamad Wan Mohamud Wan Nazaimoon Wanderley Júnior Rildo de Souza Wang Ming-Dong Wang Ningli Wang Qian Wang Xiangjun Wang Ya Xing Wang Ying-Wei Wannamethee S Goya Wareham Nicholas Wei Wenbin Weres Aneta Werner Bo Whincup Peter H Widhalm Kurt Wiecek Andrzej Wilks Rainford J Willeit Johann Willeit Peter Williams Emmanuel A Wilsgaard Tom Wojtyniak Bogdan Wong-McClure Roy A Wong Andrew Wong Tien Yin Woo Jean Wu Frederick C Wu Shouling Wyszynska Justyna Xu Haiquan Xu Liang Yaacob Nor Azwany Yan Weili Yang Ling Yang Xiaoguang Yang Yang Yasuharu Tabara Ye Xingwang Yiallouros Panayiotis K Yoosefi Moein Yoshihara Akihiro You San-Lin Younger-Coleman Novie O Yusoff Ahmad Faudzi Zainuddin Ahmad A Zakavi Seyed Rasoul Zamani Farhad Zambon Sabina Zampelas Antonis Zapata Maria Elisa Zaw Ko Ko Zejglicova Kristyna Zeljkovic Vrkic Tajana Zeng Yi Zhang Luxia Zhang Zhen-Yu Zhao Dong Zhao Ming-Hui Zhen Shiqi Zheng Yingfeng Zholdin Bekbolat Zhu Dan Zins Marie Zitt Emanuel Zocalo Yanina Zoghlami Nada Zuñiga Cisneros Julio Ezzati Majid Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants The Lancet 2021 08 957 980 398 10304 10.1016/s0140-6736(21)01330-1O'Keeffe Linda M. Simpkin Andrew J. Tilling Kate Anderson Emma L. Hughes Alun D. Lawlor Debbie A. Fraser Abigail Howe Laura D. Sex-specific trajectories of measures of cardiovascular health during childhood and adolescence: A prospective cohort study Atherosclerosis 2018 09 190 196 278 10.1016/j.atherosclerosis.2018.09.030Ji Hongwei Kim Andy Ebinger Joseph E. Niiranen Teemu J. Claggett Brian L. Bairey Merz C. Noel Cheng Susan Sex Differences in Blood Pressure Trajectories Over the Life Course JAMA Cardiology 2020 01 255 5 3 10.1001/jamacardio.2019.5306Maas Angela H E M Rosano Giuseppe Cifkova Renata Chieffo Alaide van Dijken Dorenda Hamoda Haitham Kunadian Vijay Laan Ellen Lambrinoudaki Irene Maclaran Kate Panay Nick Stevenson John C van Trotsenburg Mick Collins Peter Cardiovascular health after menopause transition, pregnancy disorders, and other gynaecologic conditions: a consensus document from European cardiologists, gynaecologists, and endocrinologists European Heart Journal 2020 12 967 984 42 10 10.1093/eurheartj/ehaa1044El Khoudary Samar R. Aggarwal Brooke Beckie Theresa M. Hodis Howard N. Johnson Amber E. Langer Robert D. Limacher Marian C. Manson JoAnn E. Stefanick Marcia L. Allison Matthew A. Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association Circulation 2020 11 142 25 10.1161/cir.0000000000000912Biglia N. Cagnacci A. Gambacciani M. Lello S. Maffei S. Nappi R. E. Vasomotor symptoms in menopause: a biomarker of cardiovascular disease risk and other chronic diseases? Climacteric 2017 04 306 312 20 4 10.1080/13697137.2017.1315089Chapman Niamh Ching Siew M. Konradi Aleksandra O. Nuyt Anne Monique Khan Taskeen Twumasi-Ankrah Betty Cho Eun J. Schutte Aletta E. Touyz Rhian M. Steckelings U. Muscha Brewster Lizzy M. Arterial Hypertension in Women: State of the Art and Knowledge Gaps Hypertension 2023 03 1140 1149 80 6 10.1161/hypertensionaha.122.20448Coutinho Thais Arterial Stiffness and Its Clinical Implications in Women Canadian Journal of Cardiology 2014 03 756 764 30 7 10.1016/j.cjca.2014.03.020Picone Dean S. Kodithuwakku Vimarsha Mayer Christopher C. Chapman Niamh Rehman Sabah Climie Rachel E. Sex differences in pressure and flow waveform physiology across the life course Journal of Hypertension 2022 09 2373 2384 40 12 10.1097/hjh.0000000000003283Mosca Lori Benjamin Emelia J. Berra Kathy Bezanson Judy L. Dolor Rowena J. Lloyd-Jones Donald M. Newby L. Kristin Piña Ileana L. Roger Véronique L. Shaw Leslee J. Zhao Dong Beckie Theresa M. Bushnell Cheryl D'Armiento Jeanine Kris-Etherton Penny M. Fang Jing Ganiats Theodore G. Gomes Antoinette S. Gracia Clarisa R. Haan Constance K. Jackson Elizabeth A. Judelson Debra R. Kelepouris Ellie Lavie Carl J. Moore Anne Nussmeier Nancy A. Ofili Elizabeth Oparil Suzanne Ouyang Pamela Pinn Vivian W. Sherif Katherine Smith Sidney C. Sopko George Chandra-Strobos Nisha Urbina Elaine M. Vaccarino Viola Wenger Nanette K. Effectiveness-Based Guidelines for the Prevention of Cardiovascular Disease in Women—2011 Update Circulation 2011 02 1243 1262 123 11 10.1161/cir.0b013e31820faaf8Issa Zeinab Seely Ellen W. Rahme Maya El-Hajj Fuleihan Ghada Effects of hormone therapy on blood pressure Menopause 2014 09 456 468 22 4 10.1097/gme.0000000000000322Mancia Giuseppe Kreutz Reinhold Brunström Mattias Burnier Michel Grassi Guido Januszewicz Andrzej Muiesan Maria Lorenza Tsioufis Konstantinos Agabiti-Rosei Enrico Algharably Engi Abd Elhady Azizi Michel Benetos Athanase Borghi Claudio Hitij Jana Brguljan Cifkova Renata Coca Antonio Cornelissen Veronique Cruickshank J. Kennedy Cunha Pedro G. Danser A.H. Jan Pinho Rosa Maria de Delles Christian Dominiczak Anna F. Dorobantu Maria Doumas Michalis Fernández-Alfonso María S. Halimi Jean-Michel Járai Zoltán Jelaković Bojan Jordan Jens Kuznetsova Tatiana Laurent Stephane Lovic Dragan Lurbe Empar Mahfoud Felix Manolis Athanasios Miglinas Marius Narkiewicz Krzystof Niiranen Teemu Palatini Paolo Parati Gianfranco Pathak Atul Persu Alexandre Polonia Jorge Redon Josep Sarafidis Pantelis Schmieder Roland Spronck Bart Stabouli Stella Stergiou George Taddei Stefano Thomopoulos Costas Tomaszewski Maciej Van de Borne Philippe Wanner Christoph Weber Thomas Williams Bryan Zhang Zhen-Yu Kjeldsen Sverre E. 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension Journal of Hypertension 2023 06 1874 2071 41 12 10.1097/hjh.0000000000003480Kobalava Zh. D. Konradi A. O. Nedogoda S. V. Shlyakhto E. V. Arutyunov G. P. Baranova E. I. Barbarash O. L. Boitsov S. A. Vavilova T. V. Villevalde S. V. Galyavich A. S. Glezer M. G. Grineva E. N. Grinstein Yu. I. Drapkina O. M. Zhernakova Yu. V. Zvartau N. E. Kislyak O. A. Koziolova N. A. Kosmacheva E. D. Kotovskaya Yu. V. Libis R. A. Lopatin Yu. M. Nebiridze D. V. Nedoshivin A. O. Ostroumova O. D. Oschepkova E. V. Ratova L. G. Skibitsky V. V. Tkacheva O. N. Chazova I. E. Chesnikova A. I. Chumakova G. A. Shalnova S. A. Shestakova M. V. Yakushin S. S. Yanishevsky S. N. Arterial hypertension in adults. Clinical guidelines 2020 Russian Journal of Cardiology 2020 04 3786 25 3 10.15829/1560-4071-2020-3-3786Curb J. David Prentice Ross L. Bray Paul F. Langer Robert D. Van Horn Linda Barnabei Vanessa M. Bloch Michael J. Cyr Michele G. Gass Margery Lepine Lisa Rodabough Rebecca J. Sidney Stephen Uwaifo Gabriel I. Rosendaal Frits R. Venous Thrombosis and Conjugated Equine Estrogen in Women Without a Uterus Archives of Internal Medicine 2006 04 772 166 7 10.1001/archinte.166.7.772Blondon Marc Wiggins Kerri L. Van Hylckama Vlieg Astrid McKnight Barbara Psaty Bruce M. Rice Kenneth M. Heckbert Susan R. Smith Nicholas L. Smoking, postmenopausal hormone therapy and the risk of venous thrombosis: a population‐based, case–control study British Journal of Haematology 2013 08 418 420 163 3 10.1111/bjh.12508Ruan X. Mueck A. O. Impact of smoking on estrogenic efficacy Climacteric 2014 07 38 46 18 1 10.3109/13697137.2014.929106Schreinlechner Michael Noflatscher Maria Reinstadler Sebastian Johannes Sommer Philip Lener Daniela Reiser Elisabeth Theurl Markus Kirchmair Rudolf Bauer Axel Marschang Peter Early onset of menopause is associated with increased peripheral atherosclerotic plaque volume and progression Atherosclerosis 2020 01 25 31 297 10.1016/j.atherosclerosis.2020.01.023Rockman Caron B. Maldonado Thomas S. Jacobowitz Glenn R. Adelman Mark A. Riles Thomas S. Hormone Replacement Therapy is Associated With a Decreased Prevalence of Peripheral Arterial Disease in Postmenopausal Women Annals of Vascular Surgery 2012 01 411 418 26 3 10.1016/j.avsg.2011.10.012Westendorp Iris C. D. in't Veld Bas A. Grobbee Diederik E. Pols Huib A. P. Meijer Wonter T. Hofman Albert Witteman Jacqueline C. M. Hormone Replacement Therapy and Peripheral Arterial Disease Archives of Internal Medicine 2003 03 2498 160 16 10.1001/archinte.160.16.2498Hodis Howard N. Mack Wendy J. Henderson Victor W. Shoupe Donna Budoff Matthew J. Hwang-Levine Juliana Li Yanjie Feng Mei Dustin Laurie Kono Naoko Stanczyk Frank Z. Selzer Robert H. Azen Stanley P. Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol New England Journal of Medicine 2016 03 1221 1231 374 13 10.1056/nejmoa1505241Chen Irene J Stanczyk Frank Z Sriprasert Intira Karim Roksana Shoupe Donna Kono Naoko Hodis Howard N Mack Wendy J Sex steroid hormones and subclinical atherosclerosis progression in postmenopausal women European Journal of Endocrinology 2025 02 248 256 192 3 10.1093/ejendo/lvaf032Anagnostis Panagiotis Mikhailidis Dimitri P. Blinc Ales Jensterle Mojca Ježovnik Mateja K. Schernthaner Gerit-Holger Antignani Pier Luigi Studen Katica Bajuk Šabović Miso Poredos Pavel The Effect of Menopause and Menopausal Hormone Therapy on the Risk of Peripheral Artery Disease Current Vascular Pharmacology 2023 10 293 296 21 5 10.2174/0115701611263345230919122907Grady Deborah Herrington David Bittner Vera Blumenthal Roger Davidson Michael Hlatky Mark Hsia Judith Hulley Stephen Herd Alan Khan Steven Newby L. Kristin Waters David Vittinghoff Eric Wenger Nanette for the HERS Research Group Cardiovascular Disease Outcomes During 6.8 Years of Hormone Therapy JAMA 2003 03 49 288 1 10.1001/jama.288.1.49Davies R.S.M. Vohra R.K. Bradbury A.W. Adam D.J. The Impact of Hormone Replacement Therapy on the Pathophysiology of Peripheral Arterial Disease European Journal of Vascular and Endovascular Surgery 2007 08 569 575 34 5 10.1016/j.ejvs.2007.06.002Polyakov D. S. Fomin I. V. Belenkov Yu. N. Mareev V. Yu. Ageev F. T. Artemjeva E. G. Badin Yu. V. Bakulina E. V. Vinogradova N. G. Galyavich A. S. Ionova T. S. Kamalov G. M. Kechedzhieva S. G. Koziolova N. A. Malenkova V. Yu. Malchikova S. V. Mareev Yu. V. Smirnova E. A. Tarlovskaya E. I. Shcherbinina E. V. Yakushin S. S. Chronic heart failure in the Russian Federation: what has changed over 20 years of follow-up? Results of the EPOCH-CHF study Kardiologiia 2021 05 4 14 61 4 10.18087/cardio.2021.4.n1628Appiah Duke Schreiner Pamela J. Demerath Ellen W. Loehr Laura R. Chang Patricia P. Folsom Aaron R. Association of Age at Menopause With Incident Heart Failure: A Prospective Cohort Study and Meta‐Analysis Journal of the American Heart Association 2016 07 5 8 10.1161/jaha.116.003769Schierbeck L. L. Rejnmark L. Tofteng C. L. Stilgren L. Eiken P. Mosekilde L. Kober L. Jensen J.-E. B. Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial BMJ 2012 10 e6409 e6409 345 oct09 2 10.1136/bmj.e6409Lindenfeld JoAnn Ghali Jalal K Krause-Steinrauf Heidi J Khan Steven Adams Kirkwood Goldman Steven Peberdy Mary Ann Yancy Clyde Thaneemit-Chen Surai Larsen Rhonda L Young James Lowes Brian Rosenberg Yves D Hormone replacement therapy is associated with improved survival in women with advanced heart failure Journal of the American College of Cardiology 2003 10 1238 1245 42 7 10.1016/s0735-1097(03)00938-0Liu Longjian Klein Liviu Eaton Charles Panjrath Gurusher Martin Lisa Warsinger Chae Claudia U. Greenland Philip Lloyd-Jones Donald M Wactawski-Wende Jean Manson JoAnn E. Menopausal Hormone Therapy and Risks of First Hospitalized Heart Failure and its Subtypes During the Intervention and Extended Postintervention Follow-up of the Women's Health Initiative Randomized Trials Journal of Cardiac Failure 2019 09 2 12 26 1 10.1016/j.cardfail.2019.09.006Baik Seo H. Baye Fitsum McDonald Clement J. Use of menopausal hormone therapy beyond age 65 years and its effects on women's health outcomes by types, routes, and doses Menopause 2024 04 363 371 31 5 10.1097/gme.0000000000002335Kirchhof Paulus Benussi Stefano Kotecha Dipak Ahlsson Anders Atar Dan Casadei Barbara Castella Manuel Diener Hans-Christoph Heidbuchel Hein Hendriks Jeroen Hindricks Gerhard Manolis Antonis S. Oldgren Jonas Popescu Bogdan Alexandru Schotten Ulrich Van Putte Bart Vardas Panagiotis Agewall Stefan Camm John Baron Esquivias Gonzalo Budts Werner Carerj Scipione Casselman Filip Coca Antonio De Caterina Raffaele Deftereos Spiridon Dobrev Dobromir Ferro José M. Filippatos Gerasimos Fitzsimons Donna Gorenek Bulent Guenoun Maxine Hohnloser Stefan H. Kolh Philippe Lip Gregory Y. H. Manolis Athanasios McMurray John Ponikowski Piotr Rosenhek Raphael Ruschitzka Frank Savelieva Irina Sharma Sanjay Suwalski Piotr Tamargo Juan Luis Taylor Clare J. Van Gelder Isabelle C. Voors Adriaan A. Windecker Stephan Zamorano Jose Luis Zeppenfeld Katja 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS European Heart Journal 2016 08 2893 2962 37 38 10.1093/eurheartj/ehw210Fang Margaret C. Singer Daniel E. Chang Yuchiao Hylek Elaine M. Henault Lori E. Jensvold Nancy G. Go Alan S. Gender Differences in the Risk of Ischemic Stroke and Peripheral Embolism in Atrial Fibrillation Circulation 2005 09 1687 1691 112 12 10.1161/circulationaha.105.553438Van Gelder Isabelle C Rienstra Michiel Bunting Karina V Casado-Arroyo Ruben Caso Valeria Crijns Harry J G M De Potter Tom J R Dwight Jeremy Guasti Luigina Hanke Thorsten Jaarsma Tiny Lettino Maddalena Løchen Maja-Lisa Lumbers R Thomas Maesen Bart Mølgaard Inge Rosano Giuseppe M C Sanders Prashanthan Schnabel Renate B Suwalski Piotr Svennberg Emma Tamargo Juan Tica Otilia Traykov Vassil Tzeis Stylianos Kotecha Dipak Dagres Nikolaos Rocca Bianca Ahsan Syed Ameri Pietro Arbelo Elena Bauer Axel Borger Michael A Buccheri Sergio Casadei Barbara Chioncel Ovidiu Dobrev Dobromir Fauchier Laurent Gigante Bruna Glikson Michael Hijazi Ziad Hindricks Gerhard Husser Daniela Ibanez Borja James Stefan Kaab Stefan Kirchhof Paulus Køber Lars Koskinas Konstantinos C Kumler Thomas Lip Gregory Y H Mandrola John Marx Nikolaus Mcevoy John William Mihaylova Borislava Mindham Richard Muraru Denisa Neubeck Lis Nielsen Jens Cosedis Oldgren Jonas Paciaroni Maurizio Pasquet Agnes A Prescott Eva Rega Filip Rossello Francisco Javier Rucinski Marcin Salzberg Sacha P Schulman Sam Sommer Philipp Svendsen Jesper Hastrup ten Berg Jurrien M Ten Cate Hugo Vaartjes Ilonca Vrints Christiaan Jm Witkowski Adam Zeppenfeld Katja Simoni Leonard Kichou Brahim Sisakian Hamayak S Scherr Daniel Cools Frank Smajić Elnur Shalganov Tchavdar Manola Sime Avraamides Panayiotis Taborsky Milos Brandes Axel El-Damaty Ahmed M Kampus Priit Raatikainen Pekka Garcia Rodrigue Etsadashvili Kakhaber Eckardt Lars Kallergis Eleftherios Gellér László Guðmundsson Kristján Lyne Jonathan Marai Ibrahim Colivicchi Furio Abdrakhmanov Ayan Suleimenovich Bytyci Ibadete Kerimkulova Alina Kupics Kaspars Refaat Marwan Bheleel Osama Abdulmajed Barysienė Jūratė Leitz Patrick Sammut Mark A Grosu Aurel Pavlovic Nikola Moustaghfir Abdelhamid Yap Sing-Chien Taleski Jane Fink Trine Kazmierczak Jaroslaw Sanfins Victor M Cozma Dragos Zavatta Marco Kovačević Dragan V Hlivak Peter Zupan Igor Calvo David Björkenheim Anna Kühne Michael Ouali Sana Demircan Sabri Sychov Oleg S Ng Andre Kuchkarov Husniddin 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) European Heart Journal 2024 08 3314 3414 45 36 10.1093/eurheartj/ehae176Antoun Ibrahim Layton Georgia R. Abdelrazik Ahmed Eldesouky Mahmoud Zakkar Mustafa Somani Riyaz Ng André The Pathophysiology of Sex Differences in Stroke Risk and Prevention in Atrial Fibrillation: A Comprehensive Review Medicina 2025 04 649 61 4 10.3390/medicina61040649Perez Marco V. Wang Paul J. Larson Joseph C. Virnig Beth A. Cochrane Barbara Curb J. David Klein Liviu Manson JoAnn E. Martin Lisa W. Robinson Jennifer Wassertheil-Smoller Sylvia Stefanick Marcia L. Effects of Postmenopausal Hormone Therapy on Incident Atrial Fibrillation Circulation: Arrhythmia and Electrophysiology 2012 11 1108 1116 5 6 10.1161/circep.112.972224Magnussen Christina Niiranen Teemu J. Ojeda Francisco M. Gianfagna Francesco Blankenberg Stefan Njølstad Inger Vartiainen Erkki Sans Susana Pasterkamp Gerard Hughes Maria Costanzo Simona Donati Maria Benedetta Jousilahti Pekka Linneberg Allan Palosaari Tarja de Gaetano Giovanni Bobak Martin den Ruijter Hester M. Mathiesen Ellisiv Jørgensen Torben Söderberg Stefan Kuulasmaa Kari Zeller Tanja Iacoviello Licia Salomaa Veikko Schnabel Renate B. Sex Differences and Similarities in Atrial Fibrillation Epidemiology, Risk Factors, and Mortality in Community Cohorts Circulation 2017 10 1588 1597 136 17 10.1161/circulationaha.117.028981Tsai Wei-Chung Haung Yaw-Bin Kuo Hsuan-Fu Tang Wei-Hua Hsu Po-Chao Su Ho-Ming Lin Tsung-Hsien Chu Chih-Sheng Jhuo Shih-Jie Lee Kun-Tai Sheu Sheng-Hsiung Chen Chung-Yu Wu Ming-Tsang Lai Wen-Ter Hormone replacement therapy and risk of atrial fibrillation in Taiwanese menopause women: A nationwide cohort study Scientific Reports 2016 04 6 1 10.1038/srep24132Wong Jorge A Rexrode Kathryn M Sandhu Roopinder K Moorthy M Vinayaga Conen David Albert Christine M Menopausal age, postmenopausal hormone therapy and incident atrial fibrillation Heart 2017 10 1954 1961 103 24 10.1136/heartjnl-2016-311002Lee Jaehoon Kim Yuntae Park Hyunji Kim Changsoo Cho Sihyun Kim Jongyoun Clinical Impact of Hormone Replacement Therapy on Atrial Fibrillation in Postmenopausal Women: A Nationwide Cohort Study Journal of Clinical Medicine 2021 12 5497 10 23 10.3390/jcm10235497Fleury Marie-Ange Clavel Marie-Annick Sex and Race Differences in the Pathophysiology, Diagnosis, Treatment, and Outcomes of Valvular Heart Diseases Canadian Journal of Cardiology 2021 02 980 991 37 7 10.1016/j.cjca.2021.02.003Rodriguez-Arias Juan José García-Álvarez Ana Sex Differences in Pulmonary Hypertension Frontiers in Aging 2021 10 2 10.3389/fragi.2021.727558Hye Tanvirul Dwivedi Pankaj Li Wei Lahm Tim Nozik-Grayck Eva Stenmark Kurt R. Ahsan Fakhrul Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension American Journal of Physiology-Lung Cellular and Molecular Physiology 2021 03 L1025 L1037 320 6 10.1152/ajplung.00559.2020Liu Aiping Schreier David Tian Lian Eickhoff Jens C. Wang Zhijie Hacker Timothy A. Chesler Naomi C. Direct and indirect protection of right ventricular function by estrogen in an experimental model of pulmonary arterial hypertension American Journal of Physiology-Heart and Circulatory Physiology 2014 06 H273 H283 307 3 10.1152/ajpheart.00758.2013Badlam Jessica B. Badesch David Brittain Evan Cordell Shannon Ding Tan Fox Kelly Hemnes Anna Loyd James Pugh Meredith Robbins Ivan Yu Chang Austin Eric D. Sex hormone exposure and reproductive factors in pulmonary arterial hypertension: a case–control study Pulmonary Circulation 2020 02 1 9 10 1 10.1177/2045894020908786Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Klinicheskie rekomendatsii. Migren'. 2024. Dostupno na: https://cr.minzdrav.gov.ru/preview-cr/295_4Nappi Rossella Tiranini Lara Sacco Simona De Matteis Eleonora De Icco Roberto Tassorelli Cristina Role of Estrogens in Menstrual Migraine Cells 2022 04 1355 11 8 10.3390/cells11081355 Lee Sa Ra Cho Moon Kyoung Cho Yeon Jean Chun Sungwook Hong Seung-Hwa Hwang Kyu Ri Jeon Gyun-Ho Joo Jong Kil Kim Seul Ki Lee Dong Ock Lee Dong-Yun Lee Eun Sil Song Jae Yen Yi Kyong Wook Yun Bo Hyon Shin Jung-Ho Chae Hee Dong Kim Tak The 2020 Menopausal Hormone Therapy Guidelines Journal of Menopausal Medicine 2020 09 69 26 2 10.6118/jmm.20000Australasian Menopause Society. Migraine headaches, menopause and MHT/HRT. Available at: https://menopause.org.au/hp/information-sheets/migraine-headaches-menopause-and-mht-hrtBritish Menopause Society. Migraine and HRT. Av. at: https://thebms.org.uk/publications/tools-for-clinicians/migraine-and-hrt/Garvey W. Timothy Garber Alan J. Mechanick Jeffrey I. Bray George A. Dagogo-Jack Samuel Einhorn Daniel Grunberger George Handelsman Yehuda Hennekens Charles H. Hurley Daniel L. McGill Janet Palumbo Pasquale Umpierrez Guillermo American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on the 2014 Advanced Framework for a New Diagnosis of Obesity as a Chronic Disease Endocrine Practice 2014 09 977 989 20 9 10.4158/ep14280.ps

The authors declare that there are no conflicts of interest present.