problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl13767problendo-13767Research ArticleДетская эндокринологияPediatric EndocrinologyКлинические рекомендации «Врожденная дисфункция коры надпочечников у детей» с комментариямиClinical practice guidelines "Congenital adrenal hyperplasia in children" with commentshttps://orcid.org/0000-0003-4915-1267ЧугуновИ. С.ChugunovI. S.

Чугунов Игорь Сергеевич - к.м.н.

Москва

Igor S. Chugunov – MD, PhD.

Moscow

chugunovigor@gmail.comhttps://orcid.org/0000-0002-9695-0806КопыловаИ. В.KopylovaI. V.

Копылова Ирина Владимировна - к.м.н.

117036, Москва, ул. Дм. Ульянова, д. 11

Irina V. Kopylova - MD, PhD

11 Dm. Ulyanova street, Moscow, 117036

iv_kopylova@mail.ruhttps://orcid.org/0000-0001-7736-5372КолодкинаА. А.KolodkinaA. A.

Колодкина Анна Александровна - к.м.н.

Москва

Anna A. Kolodkina - MD, PhD.

Moscow

anna_kolodkina@mail.ruhttps://orcid.org/0000-0002-2000-7694КалинченкоН. Ю.KalinchenkoN. Yu.

Калинченко Наталья Юрьевна - к.м.н.

Москва

Natalia Yu. Kalinchenko - MD, PhD.

Moscow

kalinnat@rambler.ruhttps://orcid.org/0000-0002-9124-294XВоронцоваМ. В.VorontsovaM. V.

Воронцова Мария Владимировна - к.м.н.

Москва

Maria V. Vorontsova - MD, PhD.

Moscow

maria.vorontsova.endo@gmail.comhttps://orcid.org/0000-0001-9621-5732БезлепкинаО. Б.BezlepkinaO. B.

Безлепкина Ольга Борисовна - д.м.н., профессор.

Москва

Olga B. Bezlepkina - PhD, Professor.

Moscow

olgabezlepkina@mail.ruhttps://orcid.org/0000-0002-5507-4627ПетерковаВ. А.PeterkovaV. A.

Петеркова Валентина Александровна - д.м.н., профессор, академик РАН.

Москва

Valentina A. Peterkova - PhD, professor, academician of Russian Academy of Medical Sciences.

Moscow

peterkovava@hotmail.comhttps://orcid.org/0000-0002-9717-9742МокрышеваН. Г.MokryshevaN. G.

Мокрышева Наталья Георгиевна - д.м.н., профессор, академик РАН.

Москва

Natalia G. Mokrysheva - MD, PhD, Professor, academician of RAS.

Moscow

mokrisheva.natalia@endocrincentr.ruНациональный медицинский исследовательский центр эндокринологии им. академика И.И. ДедоваРоссияEndocrinology Research CentreRussian FederationНациональный медицинский исследовательский центр эндокринологии им. академика И.И. Дедова; Медицинский научно-образовательный институт Московского государственного университета им. М.В. ЛомоносоваРоссияEndocrinology Research Centre; Medical Research and Educational Institute of Lomonosov Moscow State UniversityRussian Federation20262207202672386106Copyright © Чугунов И.С., Копылова И.В., Колодкина А.А., Калинченко Н.Ю., Воронцова М.В., Безлепкина О.Б., Петеркова В.А., Мокрышева Н.Г., 20262026Чугунов И.С., Копылова И.В., Колодкина А.А., Калинченко Н.Ю., Воронцова М.В., Безлепкина О.Б., Петеркова В.А., Мокрышева Н.Г.Chugunov I.S., Kopylova I.V., Kolodkina A.A., Kalinchenko N.Y., Vorontsova M.V., Bezlepkina O.B., Peterkova V.A., Mokrysheva N.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/13767

В клинических рекомендациях по врожденной дисфункции коры надпочечников у детей кратко и структурировано изложены основные сведения по эпидемиологии, этиологии, патогенезу, методам диагностики всех форм заболевания. Представлены схемы заместительной терапии глюкокортикоидными и минералокортикоидными препаратами и протоколы наблюдения за пациентами разных возрастных категорий. Настоящие клинические рекомендации разработаны и одобрены экспертным сообществом детских эндокринологов Российской ассоциации эндокринологов и утверждены советом Министерства здравоохранения РФ. В основу клинических рекомендаций включены систематические обзоры, мета-анализы, оригинальные статьи и научные работы по данной патологии в Российской Федерации и других странах. В статье обновлены комментарии и разъяснения авторов по наиболее важным аспектам диагностики и лечения врожденной дисфункции коры надпочечников в детском возрасте.

The clinical practice guidelines for congenital adrenal hyperplasia (CAH) in children clearly and systematically present the key information on the epidemiology, etiology, pathogenesis, and diagnostic methods for all forms of the disease. Protocols for glucocorticoid and mineralocorticoid replacement therapy, as well as follow-up regimens for patients in different age groups, are provided. These clinical guidelines were developed and approved by the expert community of pediatric endocrinologists from the Russian Association of Endocrinologists and endorsed by the council of the Russian Federation Ministry of Health. The guidelines are based on systematic reviews, meta-analyses, original articles, and scientific studies on this pathology conducted in the Russian Federation and other countries. This article provides updated author comments and clarifications on the most critical aspects of the diagnosis and treatment of congenital adrenal hyperplasia in childhood.

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The authors declare that there are no conflicts of interest present.