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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">problendo</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы Эндокринологии</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Endocrinology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0375-9660</issn><issn pub-type="epub">2308-1430</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/probl201258458-62</article-id><article-id custom-type="elpub" pub-id-type="custom">problendo-4680</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Двухфазный инсулиновый аналог НовоМикс 30: решение ключевых проблем инсулинотерапии двухфазными человеческими инсулинами у пациентов с сахарным диабетом 2-го типа</article-title><trans-title-group xml:lang="en"><trans-title>Biphasic insulin analog NovoMix 30 is a possible solution to overcome key problems of biphasic human insulin therapy for DM type 2 patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Surkova</surname><given-names>E V</given-names></name></name-alternatives><email xlink:type="simple">elenasurkova@mail.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2012</year></pub-date><volume>58</volume><issue>4</issue><issue-title>ТОМ 58, №4 (2012)</issue-title><fpage>58</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Surkova E.V., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Surkova E.V.</copyright-holder><copyright-holder xml:lang="en">Surkova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.probl-endojournals.ru/jour/article/view/4680">https://www.probl-endojournals.ru/jour/article/view/4680</self-uri><abstract><p>В обзоре анализируются публикации, посвященные использованию двухфазного аналога инсулина аспарт 30/70 (НовоМикс 30) в терапии пациентов с сахарным диабетом 2-го типа. Рассматриваются клинические и фармакоэкономические преимущества НовоМикс 30 перед двухфазными человеческими инсулинами. Освещаются вопросы клинической инертности врачей и психологической инсулинорезистентности пациентов, а также возможности решения ключевых проблем инсулинотерапии больных сахарным диабетом 2-го типа с помощью двухфазного аналога инсулина аспарт 30/70.</p></abstract><trans-abstract xml:lang="en"><p>This review discusses publications on the usage of biphasic analogue insulin aspart 30/70 (NovoMix 30) in the treatment of patients with type 2 diabetes mellitus. Data on the clinical and pharmaco-economic advantages of NovoMix 30 versus biphasic human insulin was analyzed. The problems of doctor's clinical inertia and patient's psychological insulin resistance, as well as possible solutions to key problems of insulin therapy with help of biphasic insulin aspart 30/70 were discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>двухфазный аналоговый инсулин</kwd><kwd>терапия инсулином</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>biphasic insulin analogs</kwd><kwd>insulin therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алгоритмы специализированной медицинской помощи больным сахарным диабетом. Под ред. И.И. Дедова, М.В. Шестаковой, 5-й вып. М 2011.</mixed-citation><mixed-citation xml:lang="en">Алгоритмы специализированной медицинской помощи больным сахарным диабетом. Под ред. И.И. Дедова, М.В. Шестаковой, 5-й вып. 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