problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl201359433-40problendo-6457Research ArticleСтатьиArticlesСиндром Прадера-Вилли: новые возможности в лечении детейPrader-Willi syndrome: new possibilities for its treatment in the childrenBogovaE A-VolevodzN N-201315082013594ТОМ 59, №4 (2013)3340Copyright © Bogova E.A., Volevodz N.N., 20132013Bogova E.A., Volevodz N.N.Bogova E.A., Volevodz N.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/6457

Синдром Прадера-Вилли (СПВ) представляет собой генетическое заболевание, главными симптомами которого являются тяжелая гиперфагия, приводящая к выраженному ожирению, задержка роста, характерные внешние особенности, сложности в обучении, поведенческие и психиатрические проблемы. В настоящее время единственным эффективным средством лечения СПВ, значительно улучшающим качество жизни пациентов, является рекомбинантный гормон роста (р-ГР). Проведен анализ многочисленных положительных эффектов и возможных рисков терапии р-ГР при СПВ.

Prader-Willi syndrome (PWS) is a genetic disease characterized by such symptoms as severe hyperphagia leading to marked obesity, growth retardation, peculiar outward appearance, cognitive disorders, behavioural and psyschiatric problems. At present, recombinant growth hormone (rGH) is the sole effective agent for the treatment of PWS; it significantly improves the quality of life of the patients with this pathology. Numerous beneficial effects and possible risks of rGH therapy of PWS are discussed.

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The authors declare that there are no conflicts of interest present.