problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl20146024-7problendo-6923Research ArticleСтатьиArticlesСостояние гонад у мальчиков с крипторхизмом в период мини-пубертатаThe state of the testis in the boys presenting with cryptorchism during the mini-pubertal periodРайгородскаяН ЮRaigorodskayaN Yunraygorodskaya@gmail.comБолотоваН ВBolotovaN V-МорозовД АMorozovD A-ЗахароваН БZakharovaN B-ГБОУ Саратовский государственный медицинский университет им. В.И. Разумовского, СаратовSaratov State Medical University named after V.I. Razumovsky, SaratovНИИ детской хирургии ФГБУ «Научный центр здоровья детей» РАМН, МоскваResearch Centre of Children's Health, Moscow201415042014602ТОМ 60, №2 (2014)47Copyright © Райгородская Н.Ю., Болотова Н.В., Морозов Д.А., Захарова Н.Б., 20142014Райгородская Н.Ю., Болотова Н.В., Морозов Д.А., Захарова Н.Б.Raigorodskaya N.Y., Bolotova N.V., Morozov D.A., Zakharova N.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/6923

Период транзиторной постнатальной активации гипоталамо-гипофизарно-гонадной системы (мини-пубертат) играет важную роль в созревании гонад и развитии репродуктивной системы. Цель исследования - оценка функционального состояния гонад у мальчиков в возрасте 2-3 мес с крипторхизмом. Клинико-гормональные исследования проведены у 32 мальчиков с паховой ретенцией гонад (1-я группа), у 10 мальчиков с односторонним абдоминальным крипторхизмом (2-я группа) и у 40 здоровых мальчиков в возрасте 2-3 мес (контроль). Обследование включало орхиометрию, генитометрию, определение гонадотропинов, тестостерона и ингибина B в сыворотке методом иммуноферментного анализа. Результаты исследования позволили диагностировать патологию половых желез у 80% мальчиков с односторонним абдоминальным крипторхизмом, выявить субклинические нарушения функции гонад у 40% мальчиков с паховой задержкой яичка.

The period of transitory postnatal activation of the hypotalamo-pitutary-gonadal axis (mini-puberty) plays an important role in the testicular maturation and the development of the reproductive system. The objective of the present study was to evaluate the functional condition of the testicles in the boys at the age of 2-3 months born with cryptorchism. A total of 32 boys presenting with inguinal retention of the testes (group 1), 10 patients with unilateral abdominal criptorchism (group 2), and 40 healthy boys ages 2-3 month (control group) were available for the clinical examination and hormonal analysis. The methods employed in the study included orchidometry and genitometry, meagurement of serum gonadotropin, testosterone, and inhibin B levels by immunoenzyme assays. The results investigations made it possible to diagnose gonadal pathology in 80% of the examinad children presenting with unilateral abdominal cryptorchism and subclinical disorders of the testicular function in 40% of the patients with inguinal retention of a testicle.

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The authors declare that there are no conflicts of interest present.