problendoПроблемы ЭндокринологииProblems of Endocrinology0375-96602308-1430Endocrinology Research Centre10.14341/probl201662640-77problendo-8124Research ArticleКлинические рекомендацииClinical guidelinesПервичный гиперпаратиреоз: клиника, диагностика, дифференциальная диагностика, методы леченияPrimary hyperparathyroidism: the clinical picture, diagnostics, differential diagnostics, and methods of treatmenthttps://orcid.org/0000-0002-8175-7886ДедовИван ИвановичDedovIvan I.

Академик РАН, директор ФГБУ ЭНЦ

MD, PhD, Professor

post@endocrincentr.ruhttps://orcid.org/0000-0002-5634-7877МельниченкоГалина АфанасьевнаMelnichenkoGalina A.

Академик РАН, директор Института клинической эндокринологии

MD, PhD, Professor

teofrast2000@mail.ruМокрышеваНаталья ГеоргиевнаMokryshevaNatalia G.

д.м.н., Руководитель  Центра патологии околощитовидных желез

MD, PhD

nm70@mail.ruРожинскаяЛюдмила ЯковлевнаRozhinskayaLiudmila Y.

Д.м.н., профессор, главный научный сотрудник отделения нейроэндокринологии и остеопатий

MD, PhD, Professor

rozhinskaya@rambler.ruКузнецовНиколай СергеевичKusnezovNikolay S.

Д.м.н., профессор, заведующий отделом хирургии

MD, PhD

post@endocrincentr.ruПигароваЕкатерина АлександровнаPigarovaEkaterina A.

К.м.н., ведущий научный сотрудник отделения нейроэндокринологии и остеопатий

MD, PhD

kpigarova@gmail.comЕремкинаАнна КонстантиновнаEremkinaAnna K.

к.м.н., Научный сотрудник Центра патологии околощитовидных желез

MD, PhD

Karintija@yandex.ruЕгшатянЛилит ВаниковнаEgshatyanLilit V.

к.м.н., старший научный сотрудник Центра патологии околощитовидных желез

MD, PhD

eghshatyanl@rambler.ruМамедоваЕлизавета ОктаевнаMamedovaElizaveta O.

Аспирант Центра патологии околощитовидных желез

MD

lilybet@mail.ruКрупиноваЮлия АлександровнаKrupinovaJulia A.

научный сотрудник Центра патологии околощитовидных желез

MD

j.krupinova@gmail.comФГБУ "Эндокринологический научный центр" Минздрава РоссииРоссияEndocrinology Research Centre, MoscowRussian Federation2016120120176264077Copyright © Дедов И.И., Мельниченко Г.А., Мокрышева Н.Г., Рожинская Л.Я., Кузнецов Н.С., Пигарова Е.А., Еремкина А.К., Егшатян Л.В., Мамедова Е.О., Крупинова Ю.А., 20162016Дедов И.И., Мельниченко Г.А., Мокрышева Н.Г., Рожинская Л.Я., Кузнецов Н.С., Пигарова Е.А., Еремкина А.К., Егшатян Л.В., Мамедова Е.О., Крупинова Ю.А.Dedov I.I., Melnichenko G.A., Mokrysheva N.G., Rozhinskaya L.Y., Kusnezov N.S., Pigarova E.A., Eremkina A.K., Egshatyan L.V., Mamedova E.O., Krupinova J.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.probl-endojournals.ru/jour/article/view/8124

В настоящее время первичный гиперпаратиреоз (ПГПТ) является третьим по распространенности после сахарного диабета и патологии щитовидной железы эндокринным заболеванием и одной из наиболее частых причин остеопороза и переломов среди вторичных остеопатий. ПГПТ относится к социально значимым проблемам в связи с вовлечением в патологический процесс большинства органов и систем. В последние годы существенно изменилось представление об эпидемиологии, клинике и тактике ведения пациентов с ПГПТ в результате значительного увеличения заболеваемости за счет выявления мягкой формы. Современная тактика ведения пациентов с ПГПТ определяется степенью тяжести клинических проявлений. Учитывая актуальность проблемы, создана Рабочая группа для разработки Федеральных рекомендаций, основанных на принципах доказательной медицины. Опыт международных и отечественных экспертов стал основой для создания Федеральных клинических рекомендаций по первичному гиперпаратиреозу, в которых собрана имеющаяся информация по данной проблеме.

Primary hyperparathyroidism (PHT) is the third most common endocrine disorder in men and women after diabetes mellitus and thyroid disease and one of the most frequent causes of osteoporosis and fractures among the secondary osteopathy. PHT refers to socially significant problems in connection with involvement in the pathological process of the majority of organs and system In recent years, the conception of epidemiology, clinic and tactics of management of patients with PHT has changed due to significant increase of morbidity at the expense of identification of mild forms of disease. The modern management concept tactics depends on clinical manifestations. Bearing in mind the importance of the problem under consideration, the working group was set up for the development of federal recommendations on the treatment of PHT based on the principles of evidence-based medicine. The experience accumulated by the domestic and international experts was summarized in the federal clinical guidelines on PHT.

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The authors declare that there are no conflicts of interest present.