The effect of estrogen deficiency on rat ganglioside metabolism
https://doi.org/10.14341/probl199743637-39
Abstract
The effect of estrogen insufficiency on the formation of gangliosides from precursors is studied. Oophorectomy changes the production of gangliosides in the heart, skeletal muscles, fatty tissue, and pancreas. Estrogen insufficiency is paralleled by decrease of cardiac monosialogangliosides G^j and GM3> skeletal muscle disialogangliosides GDlb and GDla and monosialogangliosides Gmi end Gmj, fatty tissue disialoganglioside GDlb and monosialogangliosides G^] and GM3> and pancreatic monosialoganglioside GMI. The findings indicate that estrogens can contribute to regulation of ganglioside metabolism.
About the Authors
T. S. SaatovInstitute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Uzbekistan
E. I. Isaev
Institute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Uzbekistan
M. Zh. Ergashova
Institute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Uzbekistan
O. Yu. Kukina
Institute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Russian Federation
A. P. An
Institute of Biochemistry, Academy of Sciences of the Republic of Uzbekistan
Russian Federation
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Review
For citations:
Saatov T.S., Isaev E.I., Ergashova M.Zh., Kukina O.Yu., An A.P. The effect of estrogen deficiency on rat ganglioside metabolism. Problems of Endocrinology. 1997;43(6):37-39. (In Russ.) https://doi.org/10.14341/probl199743637-39
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