Effect of islet cell culture xenotransplantation on alloxan diabetes course in rats fed diets with different protein content
https://doi.org/10.14341/probl12146
Abstract
The authors present data- on the protective effect of newborn rabbits pancreatic islet cell culture xenotransplantation of Langerhans’ islets P-cells of rats with alloxan diabetes. This effect was the most marked in rats fed diets with normal or increased protein content. The authors discuss a possible stimulating effect of rabbit islet cell culture xenooransplantation on regeneration processes in recipient rat pancreatic islets. This effect was better pronounced in rats kept on rations with increased protein content. Further experiments will help more accuretaly define the indications for therapy of insulindependent diabetes mellitus by xenokansplantations of islet cell cultures.
About the Authors
R. Ye. Sadykova
Institute of Nutrition; Research Institute for Transplantology and Artificial Organs
Russian Federation
Russian Federation
N. N. Skaletsky
Institute of Nutrition; Research Institute for Transplantology and Artificial Organs
Russian Federation
Russian Federation
A. V. Dreval
Institute of Nutrition; Research Institute for Transplantology and Artificial Organs
Russian Federation
Russian Federation
L. A. Kirsanova
Institute of Nutrition; Research Institute for Transplantology and Artificial Organs
Russian Federation
Russian Federation
P. I. Shishko
Institute of Nutrition; Research Institute for Transplantology and Artificial Organs
Russian Federation
Russian Federation
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Review
For citations:
Sadykova R.Ye., Skaletsky N.N., Dreval A.V., Kirsanova L.A., Shishko P.I. Effect of islet cell culture xenotransplantation on alloxan diabetes course in rats fed diets with different protein content. Problems of Endocrinology. 1994;40(4):45-47. (In Russ.) https://doi.org/10.14341/probl12146
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