Iodine Deficiency Disorders: Current State of the Problem in the Bryansk Region
https://doi.org/10.14341/probl12793
Abstract
BACKGROUND: The Bryansk region is one of the regions of the Russian Federation most affected by the accident at the Chernobyl nuclear power plant on April 26, 1986.In the conditions of a chronic uncompensated deficiency of iodine in the diet in the first months after the accident, an active seizure of radioactive iodine by the thyroid tissue took place, which inevitably resulted in an increase in thyroid diseases from the population in the future. The article presents the results of a control and epidemiological study carried out in May 2021 by specialists of the National Medical Research Center of Endocrinology of the Ministry of Health of Russia, aimed at assessing the current state of iodine provision in the population of the Bryansk region.
AIM: Assessment of iodine supply of the population of the Bryansk region.
MATERIALS AND METHODS: The research was carried out in secondary schools of three districts of the Bryansk region (Bryansk, Novozybkov and Klintsy).The study included 337 schoolchildren of pre-pubertal age (8–10 years), all children underwent: measurement of height and weight immediately before the doctor’s examination, which included palpation of the thyroid gland (thyroid gland); Thyroid ultrasound using a portable device LOGIQe (China) with a multi-frequency linear transducer 10–15 MHz; determination of iodine concentration in single portions of urine. A qualitative study for the presence of potassium iodate in samples of table salt (n = 344) obtained from households and school canteens was carried out on the spot using the express method.
RESULTS: According to the results of a survey of 337 pre-pubertal children, the median urinary iodine concentration (mCIM) is 98.3 μg / L (range from 91.5 to 111.5 μg / L, the proportion of urine samples with a reduced iodine concentration was 50.1%). According to the ultrasound of the thyroid gland, 17% of the examined children had diffuse goiter, the frequency of which varied from 9.4 to 29% in the areas of study. The share of iodized salt consumed in the families of schoolchildren in the study areas was 17.8% (values range from 15.6 to 19%), which indicates an extremely low level of iodized salt consumption by the population. All salt used for cooking in school canteen areas of the study was iodized, which confirms compliance with the requirements of SanPiN 2.4.5.2409–08.
CONCLUSION: Despite the active implementation in the Bryansk region of various preventive programs of IDD and social activities to promote the use of iodized salt, in the absence of mass prevention with the help of iodized salt to date, their unsatisfactory results should be noted.
About the Authors
E. A. TroshinaRussian Federation
Ekaterina A. Troshina, MD, PhD, Professor
eLibrary SPIN: 8821-8990
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
N. P. Makolina
Russian Federation
Natalya P. Makolina, MD
eLibrary SPIN: 7210-9512
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
E. S. Senyushkina
Russian Federation
Evgeniya S. Senyushkina, MD
11 Dm. Ulyanova street, 117036 Moscow
eLibrary SPIN: 4250-5123
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
L. V. Nikankina
Russian Federation
Larisa V. Nikankina, PhD
eLibrary SPIN: 2794-0008
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
N. M. Malysheva
Russian Federation
Natalia M. Malysheva, PhD
eLibrary SPIN: 5793-2550
Moscow
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
A. V. Fetisova
Russian Federation
Alla V. Fetisova, MD
eLibrary SPIN: 3420-7859
Bryansk
Competing Interests:
Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
References
1. Dedov II. Ioddefitsitnye zabolevaniya v Rossiiskoi Federatsii. Ed. by Dedov II, Gerasimov GA, Sviridenko NYu. Moscow; 1999. 32 p. (In Russ.)
2. Troshina EA, Platonova NM, Abdulkhabirova FM, Gerasimov GA. Iododefitsitnye zabolevaniya v Rossiiskoi Federatsii: vremya prinyatiya reshenii. Ed. by. Dedov II, Mel’nichenko GA. Moscow: OAO «Konti-Print»; 2012. 232 p. (In Russ.)
3. Yadav K, Pandav C. National Iodine Deficiency Disorders Control Programme: Current status & future strategy. Indian J Med Res. 2018;148(5):503. doi: https://doi.org/10.4103/ijmr.IJMR_1717_18
4. Gerasimov GA, Figge D. Chernobyl’: dvadtsat’ let spustya. Clinical and experimental thyroidology. 2006;2(2):5-14. (In Russ.) doi: https://doi.org/10.14341/ket2006225-14
5. Doklad Ob ispolnenii programmy «Preduprezhdenie i lechenie zabolevanii shchitovidnoi zhelezy na territorii Bryanskoi oblasti» v 2001-2002 gg. (In Russ.)
6. Korobova EM, Berezkin VYu, Kolmykova LI, et al. Iodine deficiency in agricultural landscapes of the Bryansk Region. Vestnik RUDN, seriya Ekologiya i bezopasnost’ zhiznedeyatel’nosti. 2016;3:57-65. (In Russ.)
7. Gerasimov G, Alexandrova G, Arbuzova M, et al. Iodine defficiency disorders (IDD) in regions of Russia affected by Chernobyl. In Karaoglou A, Desmet G, Kelly GN, Menzel HG, editors. The radiological consequences of the Chernobyl accident. Brussels: European Commission; 1996:813–815.
8. Yakovleva IN. Zabolevaniya shchitovidnoi zhelezy u detei, podvergshikhsya radiatsionnomu vozdeistviyu v rezul’tate avarii na Chernobyl’skoi AES: epidemiologiya, patogenez, obosnovanie taktiki lecheniya, profilaktika: [dissertation]. M.; 2008. (In Russ.)
9. Remennik LV, Starinsky VV, Mokina VD, et al. Malignant Neoplasms on the Territories of Russia Damaged Owing to the Chernobyl Accident. The radiological consequences of the Chernobyl accident. Brussels: European Commission. 1996: 825-828.
10. Stsjazhko VA, Tsyb AF, Tronko ND, et al. Childhood thyroid cancer since accident at Chernobyl. BMJ. 1995;310(6982):801-801. doi: https://doi.org/10.1136/bmj.310.6982.801
11. Tsyb AF, Parshkov EM, Ivanov VK, et al. Disease indices of thyroid and their dose dependence in children and adolescents affected as a result of the Chernobyl accident. Ed. by Nagataki S. Amsterdam: Elsevier Science; 1994:9-19.
12. Formy gosstatotchetnosti №63 «Svedeniya o zabolevaniyakh, svyazannykh s mikronutrientnoi nedostatochnost’yu» (2010-2012 gg.) (In Russ.)
13. Zlokachestvennye novoobrazovaniya v Rossii v 2017 godu. Ed by Kaprina AD, Starinskogo VV, Petrovoi GV. Moscow: MNIOI im. P.A. Gertsena filial FGBU «NMITs radiologii» Minzdrava Rossii; 2018. 250 p. (In Russ.)
14. Troshina EA, Platonova NM, Panfilova EA. Dynamics of epidemiological indicators of thyroid pathology in the population of the Russian Federation: analytical report for the period 2009–2018. Problems of Endocrinology. 2021;67(2):10-19. (In Russ.) doi: https://doi.org/10.14341/probl12433
15. Zimmermann MB, Hess SY, Molinari L, et al. New reference values for thyroid volume by ultrasound in iodine-sufficient schoolchildren: a World Health Organization/Nutrition for Health and Development Iodine Deficiency Study Group Report. Am J Clin Nutr. 2004;79(2):231-237. doi: https://doi.org/10.1093/ajcn/79.2.231
16. Troshina EA, Mazurina NV, Senyushkina ES, et al. Monitoring of iodine deficiency disorders in the Republic of Tyva. Problems of Endocrinology. 2021;67(1):60-68. (In Russ.) doi: https://doi.org/10.14341/probl12715
17. Troshina EA, Senyushkina ES, Makolina NP, et al. Iodine Deficiency Disorders: Current State of the Problem in the Republic of Crimea. Clin Exp Thyroidol. 2021;16(4):19-27. (In Russ.) doi: https://doi.org/10.14341/ket12700
Supplementary files
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1. Drawing. 1. Analysis of the frequency distribution of the concentration of iodine in the urine of the examined schoolchildren. | |
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2. Figure 2a. Results of determining the presence of iodine in table salt from households. Figure 2b. Photo of the result of an express test to determine the presence of iodine in table salt (dark blue coloration of salt samples confirms the presence of potassium iodate in them). | |
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3. Figure 3. Employees of the Federal State Budgetary Institution "National Medical Research Center of Endocrinology" examine children in the Bryansk region. | |
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Type | Исследовательские инструменты | |
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For citations:
Troshina E.A., Makolina N.P., Senyushkina E.S., Nikankina L.V., Malysheva N.M., Fetisova A.V. Iodine Deficiency Disorders: Current State of the Problem in the Bryansk Region. Problems of Endocrinology. 2021;67(4):84-93. https://doi.org/10.14341/probl12793

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