Optimization of an integrated approach to voice correction for endocrinopathies (analytical review)
https://doi.org/10.14341/probl12822
Abstract
Dysphonia is a symptom of many endocrine pathologies. Hoarseness, voice fatigue, decrease of the voice pitch, reduce of the range are typical complaints for hypothyroidism, caused by an increased amount of polysaccharides and accumulation of fluid in the lamina propria of the vocal folds. An excess of growth hormone causes an overproduction of insulin-like growth factor-1, which leads to abnormalities in the craniofacial region and proliferation of the upper respiratory tract tissues, including thickening of the laryngeal cartilages, vocal folds and decreasing of the voice pitch. Hyperglycemia, changes in the balance of fluid and electrolytes in diabetes mellitus can indirectly affect the voice: xerostomia complicates phonation due to impaired hydration of the laryngeal mucosa, diabetic neuropathy often disrupts the work of the laryngeal muscles involved in voice formation. Voice changes are observed not only in endocrine disorders, but also during puberty, the phases of the menstrual cycle and during menopause. Laryngeal structures are modified under the influence of hormones and external factors, which generally changes pitch and intensity of the voice, timbre and resonance, articulation and prosodic characteristics. The purpose of this review is to summarize and systematize data on physiological and pathological voice changes in patients of different age groups and sex. The possibilities of a multidisciplinary approach to rational voice correction are demonstrated.
About the Authors
S. V. StarostinaRussian Federation
Svetlana V. Starostina, professor
Sechenov University, 119991, Moscow
SPIN-код: 1675-1556
Ya. A. Statsenko
Russian Federation
Yaroslava A. Statsenko, student
Moscow
SPIN-код: 7026-4469
V. M. Svistushkin
Russian Federation
Valeriy M. Svistushkin, professor
Moscow
SPIN-код: 9040-5720
References
1. Hari Kumar KVS, Garg A, Ajai Chandra NS, et al. Voice and endocrinology. Indian J Endocrinol Metab. 2016;20(5):590-594. doi: https://doi.org/10.4103/2230-8210.190523
2. Altman KW, Haines GK 3rd, Vakkalanka SK, et al. Identification of thyroid hormone receptors in the human larynx. Laryngoscope. 2003;113(11):1931-1934. doi: https://doi.org/10.1097/00005537-200311000-00014
3. Voelter Ch, Kleinsasser N, Joa P, et al. Detection of hormone receptors in the human vocal fold. Eur Arch Otorhinolaryngol. 2008;265(10):1239-1244. doi: https://doi.org/10.1007/s00405-008-0632-x
4. Abitbol J, Brux J, Millot G, et al. Does a hormonal vocal cord cycle exist in women? Study of vocal premenstrual syndrome in voice performers by videostroboscopy-glottography and cytology on 38 women. J Voice. 1989;3(2):157-162. doi: https://doi.org/10.1016/S0892-1997(89)80142-0
5. Shilenkova VV. Disfonii i golos. Yaroslavl’: Avers Plyus; 2018. (in Russ.).
6. El-Shafie KT. Hypothyroidism presenting with dysarthria. J Family Community Med. 2003;10(2):55-57.
7. Stöllberger C, Finsterer J, Brand E, Tschabitscher D. Dysarthria as the leading symptom of hypothyroidism. Am J Otolaryngol. 2001;22(1):70-72. doi: https://doi.org/10.1053/ajot.2001.20698
8. Mortimore IL, Marshall I, Wraith PK, et al. Neck and total body fat deposition in nonobese and obese patients with sleep apnea compared with that in control subjects. Am J Respir Crit Care Med. 1998;157(1):280-283. doi: https://doi.org/10.1164/ajrccm.157.1.9703018
9. Roy N, Merrill RM, Pierce J, Sundar KM. Voice Disorders in Obstructive Sleep Apnea: Prevalence, Risk Factors, and the Role of CPAP. Ann Otol Rhinol Laryngol. 2019;128(3):249-262. doi: https://doi.org/10.1177/0003489418819541
10. Nam IC, Park YH. Pharyngolaryngeal symptoms associated with thyroid disease. Curr Opin Otolaryngol Head Neck Surg. 2017;25(6):469-474. doi: https://doi.org/10.1097/MOO.0000000000000404
11. Bellantone R, Lombardi CP, Bossola M, et al. Total thyroidectomy for management of benign thyroid disease: review of 526 cases. World J Surg. 2002;26(12):1468-1471. doi: https://doi.org/10.1007/s00268-002-6426-1
12. Viana Baptista SIR, Lott DG, Almeida SCC, et al. Preoperative Voice Characteristics in Thyroid Patients. J Voice. 2021;35(5):809.e1-809.e6. doi: https://doi.org/10.1016/j.jvoice.2019.12.024
13. Bartsch DK, Dotzenrath C, Vorländer C, et al. The StuDoQ/Thyroid Study Group TSS. Current Practice of Surgery for Benign Goitre-An Analysis of the Prospective DGAV StuDoQ|Thyroid Registry. J Clin Med. 2019;8(4):477. doi: https://doi.org/10.3390/jcm8040477
14. Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid : official journal of the American Thyroid Association. 2016;26(1):1-133. doi: https://doi.org/10.1089/thy.2015.0020
15. Chandrasekhar SS, Randolph GW, Seidman MD, et al. American Academy of Otolaryngology-Head and Neck Surgery. Clinical practice guideline: improving voice outcomes after thyroid surgery. Otolaryngol Head Neck Surg. 2013;148(6):1-37. doi: https://doi.org/10.1177/0194599813487301
16. Junuzović-Žunić L, Ibrahimagić A, Altumbabić S. Voice Characteristics in Patients with Thyroid Disorders. Eurasian J Med. 2019;51(2):101-105. doi: https://doi.org/10.5152/eurasianjmed.2018.18331
17. Wolters TLC, Roerink SHPP, Drenthen LCA, et al. Voice Characteristics in Patients with Acromegaly during Treatment. J Voice. 2021;35(6):932.e13-932.e27. doi: https://doi.org/10.1016/j.jvoice.2020.01.006
18. Kadakia S, Carlson D, Sataloff R. The Effect of Hormones on the Voice. J Sing. 2013;69(5):571-574.
19. Saboor Aftab SA, Kumar S, Barber TM. The role of obesity and type 2 diabetes mellitus in the development of male obesity-associated secondary hypogonadism. Clin Endocrinol (Oxf). 2013;78(3):330-337. doi: https://doi.org/10.1111/cen.12092
20. Gugatschka M, Lichtenwagner S, Schwetz V, et al. Subjective and objective vocal parameters in women with polycystic ovary syndrome. J Voice. 2013;27(1):98-100. doi: https://doi.org/10.1016/j.jvoice.2012.07.007
21. Hannoun A, Zreik T, Husseini ST, et al. Vocal changes in patients with polycystic ovary syndrome. J Voice. 2011;25(4):501-504. doi: https://doi.org/10.1016/j.jvoice.2009.12.005
22. Aydin K, Akbulut S, Demir MG, et al. Voice characteristics associated with polycystic ovary syndrome. Laryngoscope. 2016;126(9):2067-2072. doi: https://doi.org/10.1002/lary.25818
23. Dedov II, Shestakova MV, Mayorov AYu, et al. Standards of specialized diabetes care. Diabetes Mellitus. 2019;22(S1):1-144 (In Russ.). doi: https://doi.org/10.14341/DM221S1
24. Hamdan AL, Kurban Z, Azar ST. Prevalence of phonatory symptoms in patients with type 2 diabetes mellitus. Acta Diabetol. 2013;50(5):731-736. doi: https://doi.org/10.1007/s00592-012-0392-3
25. Biryulina NYu. Narusheniya golosa u podrostkov v period mutatsii. Rossiiskaya otorinolaringologiya. 2003;1:30-32. ( in Russ.).
26. Lim JY, Lim SE, Choi SH, et al. Clinical characteristics and voice analysis of patients with mutational dysphonia: clinical significance of diplophonia and closed quotients. J Voice. 2007;21(1):12-19. doi: https://doi.org/10.1016/j.jvoice.2005.10.002
27. Ghaemi H, Dehqan A, Mahmoodi-Bakhtiari B, Scherer RC. Voice Changes During Pregnancy Trimesters in Iranian Pregnant Women. J Voice. 2020;34(3):358-363. doi: https://doi.org/10.1016/j.jvoice.2018.09.016
28. Lã FM, Sundberg J. Pregnancy and the singing voice: reports from a case study. J Voice. 2012;26(4):431-439. doi: https://doi.org/10.1016/j.jvoice.2010.10.010
29. Cassiraga VL, Castellano AV, Abasolo J, et al. Pregnancy and voice: changes during the third trimester. J Voice. 2012;26(5):584-586. doi: https://doi.org/10.1016/j.jvoice.2011.10.004
30. Boikova NE. Sravnitel’naya kharakteristika fonetogramm zhenskogo golosa v razlichnye vozrastnye periody. Rossiiskaya otorinolaringologiya. 1998;2:102-104. ( In Russ.).
31. D’yachenko EYu. Presbifoniya. Foniatricheskie aspekty. Materialy mezhregional’noi nauchno-prakticheskoi konferentsii otorinolaringologov Sibiri i Dal’nego Vostoka s mezhdunarodnym uchastiem «Aktual’nye voprosy otorinolaringologii»; 2016 Jun 30; Blagoveshchensk; 2016;14:166-170. ( In Russ.).
32. Shilenkova VV, Bestolkova OS. Presbifoniya. Vozrastnye izmeneniya akusticheskikh parametrov golosa. Vestnik otorinolaringologii. 2013;78(6):24-27. (In Russ.).
33. Klinicheskie rekomendatsii MZ RF «Parezy i paralichi gortani». Moscow: Natsional’naya meditsinskaya assotsiatsiya otorinolaringologov; 2020. 32 p. (In Russ.).
34. Makarin VA, Uspenskaya AA. Alekseev MA, et al. Intraoperative neuromonitoring in thyroid and parathyroid surgery: indications and method. Endocrine Surgery. 2016;10(2):5-17. (In Russ.)]. doi: https://doi.org/10.14341/serg201625-17
35. Palamarchuk VA. Vliyanie neselektivnoi innervatsii gortani na osnovnye kharakteristiki golosa. Mezhdunarodnyi endokrinologicheskii zhurnal. 2014;1(57):114-117. (In Russ.).
36. Svistushkin VM, Karpova OY. The modern approach to the conservative treatment of the patients presenting with postoperative bilateral vocal fold palsy. Vestnik otorinolaringologii. 2017;82(1):25-29. (In Russ.). doi: https://doi.org/10.17116/otorino201782125-29
37. Starostina SV, Mareev OV, Nikolenko VN. Mediafixation of the vocal cord through the external approach in the patients presenting with unilateral laryngeal paralysis. Vestnik otorinolaringologii. 2013;78(6):51-54. (In Russ.).
Supplementary files
Review
For citations:
Starostina S.V., Statsenko Ya.A., Svistushkin V.M. Optimization of an integrated approach to voice correction for endocrinopathies (analytical review). Problems of Endocrinology. 2022;68(2):48-55. (In Russ.) https://doi.org/10.14341/probl12822

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