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The role of estriol in the treatment of atrophy of the mucous membrane of the lower genitourinary tract in postmenopausal women

https://doi.org/10.14341/probl13198

Abstract

Studies of recent decades show a steady increase in the average life expectancy of a person, and women in particular. The World Health Organization predicts a four-fold increase in the number of women over 70 by 2030, and many of them over the age of 45 may face menopausal problems. Menopause is a physiological state in a woman’s life, during which, against the background of age-related changes, there is a gradual decrease and shutdown of ovarian function and the cessation of estrogen production. Genitourinary syndrome occurs in every third woman in this period. Estriol is the main estrogen that specifically addresses problems associated with estrogen deficiency: dyspareunia, dryness and itching in the vagina and lower genitourinary tract, urinary incontinence, moderate urinary incontinence, and recurrent vulvovaginitis and cystitis. Vulvovaginal dystrophy in women of the older age group is a multidisciplinary problem at the intersection of gynecology, urology and dermatology, which can and should be solved to prevent more severe gynecological and urological pathologies.

About the Authors

E. N. Andreeva
Endocrinology Research Centre; Evdokimov Moscow State University of Medicine and Dentistry
Russian Federation

Elena N. Andreeva - MD, PhD, DSc

11 Dm. Ulyanov str., Moscow, 117036

SPIN-код: 1239-2937


Competing Interests:

None



E. V. Sheremetyeva
Endocrinology Research Centre
Russian Federation

Ekaterina V. Sheremetyeva - MD, PhD

11 Dm. Ulyanov str., Moscow, 117036

SPIN-код: 9413-5136


Competing Interests:

None



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For citations:


Andreeva E.N., Sheremetyeva E.V. The role of estriol in the treatment of atrophy of the mucous membrane of the lower genitourinary tract in postmenopausal women. Problems of Endocrinology. 2022;68(6):157-163. (In Russ.) https://doi.org/10.14341/probl13198

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)