Proliferative activity of the epithelial sheet of the mucous membrane in the lower airways during experimental diabetes mellitus
https://doi.org/10.14341/probl201359327-29
Abstract
The present study was designed to develop the experimental model of diabetes mellitus based on 5-6 month-old Wistar rats weighing 234.00±2.64 g (n=47). Diabetes was induced by a single intraperitoneal administration of streptozotocin (60 mg/kg, "Sigma", USA) in a 0.1 M citrate buffer solution, pH 4.5. The control group was comprised of 43 intact male rats. The animals with experimental diabetes had a reduced number of secretory cell nuclei per unit area of the epithelial sheet of the bronchial tree; the area of epitheliocyte nuclei also decreased.
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Review
For citations:
Pivovarova O.A., Man'kovskiĭ B.N. Proliferative activity of the epithelial sheet of the mucous membrane in the lower airways during experimental diabetes mellitus. Problems of Endocrinology. 2013;59(3):27-29. (In Russ.) https://doi.org/10.14341/probl201359327-29
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