Hyperuricemia as a component of metabolic syndrome X

Abstract

The authors analyze the results of epidemiological survey of a random sampling of population (n=594, aged 16 to 65, mean age 39.4±0.5 years). The study was aimed at elucidating the relationship between hyperuricemia and the principal symptoms of the metabolic X syndrome: obesity, arterial hypertension, hyperlipoproteinemia, hyperinsulinemia, and carbohydrate disorders of diabetic nature (impaired glucose tolerance and type II diabetes mellitus). Calculation of the association coefficient (Ka) showed that at the population level, hyperuricemia was definitely associated with arterial hypertension (Ka=0.46), type IV hyperlipoproteinemia (Ka=0.5), obesity with body weight index more than 30 kg/m² (Ka—0.51), hyperinsulinemia (Ka=0.57), and carbohydrate disorders of diabetic origin (Ka=0.62).