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Prevalence of retinopathy in patients with type 2 diabetes mellitus

https://doi.org/10.14341/probl20065246-8

Abstract

The fact that diabetic retinopathy (DP) exists at the preclinical stage of evolution of type 2 diabetes mellitus (DM-2) cannot be' explained in the context of the commonly accepted theory of the etiopathogenesis of diabetic microangiopathy. The purpose of the study was to explore the prevalence of DR among patients with new-onset DM-2 and to analyze the possible causes of development of this complication at an early stage of the disease. The prevalence of DR among patients with new-onset DM-2 was found to be 16.4%. In the new-onset DM-2 patients aged above 45 years, the odds ratio for DR. is 2.6 times greater than that in those aged under 45 years. Based on the results of the study, the authors suggest that there are pathogenetic mechanisms responsible for the initiation of diabetic microvascular pathology to the stabilization of hyperglycemia at the stage of decreased glucose tolerance.

About the Authors

D S Metrevell
Кафедра эндокринологии (зав. - проф. Д. С. Метревели) Государственной медицинской академии Грузии, Тбилиси


M Z Sulkhanlshvili
Кафедра эндокринологии (зав. - проф. Д. С. Метревели) Государственной медицинской академии Грузии, Тбилиси


M Z Margvelashvilt
Кафедра эндокринологии (зав. - проф. Д. С. Метревели) Государственной медицинской академии Грузии, Тбилиси


References

1. Дедов И. И., Шестакова М. В., Миленькая Т. М. Сахарный диабет: ретинопатия, нефропатия. - М., 2001.

2. Дедов И. И., Сунцов Ю. И., Смирнов С. В. и др. // Сахарный диабет. - 2003. - № 3 (20). - С. 2-4.

3. Скоробогатова Е. С., Яковлева Л. В., Мельниченко Г. А. // Сахарный диабет. - 2003. - № 2 (19). - С. 32-34.

4. Epilnfo 6. A Word Processing, Database and Statistics Program for Public Health. Centers For Disease Control and Prevention (CDC), U. S. A. - Geneva, 1994.

5. Harris M. I., Klein R., Welbom T. A., Knuiman M. W. // Diabetes Care. - 1992. - Vol. 15, N 7. - P. 815-819.

6. Нiller Т.А., Pedula K. L. // Diabetes Care. -:2003. -Vol. 26, N 11. - P. 2999-3005.

7. Kohner E. M., Aldington S. J., Stratton IM. et al. // Arch. Ophthalmol. - 1998. - Vol. 116, N 3. - P. 297-303.

8. Krakoff J., Lindsay R. S., Looker H. С. et al. // Diabetes Care. -2003. - Vol. 26, N 1. - P. 76-81.

9. Krans H. M. J., Porta M., Keen H. et al. // G. Ital. Diabetol. -1995. - Vol. 15, N 1. - P. 4-77.

10. Leiden H. A., Dekker J. M., Moll A. C. et al. // Diabetes Care. - 2002. - Vol. 25, N 8. - P. 1320-1325.

11. Lorenzo C, Okoloise M., Williams K. et al. // Diabetes Care. -2003. - Vol. 26, N 11. - P. 3153-3159.

12. Malone J. I., Pavan P. R., Morrison A. D., Cuthbertson D. D. // Diabetes Care. - 2001. - Vol. 24, N 3. - P. 522-526.

13. Screening for Diabetic Retinopathy In Europe: A Field Guide-Book/ Eds E. M. Kohner, M. Porta. - Pisa, 1992.

14. Seraday M., Damiano M., Lapartosa S. et al. // Diabet. Metab. -2003. - Vol. 29. - Serie 2. - P. 4S40.

15. Singleton J., Smith A., RusselJ. W., Feldman E. L. // Diabetes. -2003. - Vol. 52, N 12. - P. 2867-2873.

16. Tyrberg M., Melander A., Llndblad U. // Diabetologia. - 2004. -Vol. 47. - Suppl. 1. - P. A380.

17. Young B. A., Maynard C., Boyko E. J. // Diabetes Care. - 2003. - Vol. 26, N 8. - P. 2392-2399.


Review

For citations:


Metrevell D.S., Sulkhanlshvili M.Z., Margvelashvilt M.Z. Prevalence of retinopathy in patients with type 2 diabetes mellitus. Problems of Endocrinology. 2006;52(4):6-8. (In Russ.) https://doi.org/10.14341/probl20065246-8

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)