Preview

Problems of Endocrinology

Advanced search

Apidra is a new insulin analogue for the treatment of vascular complications in diabetes

https://doi.org/10.14341/probl200753335-38

Abstract

To achieve glycemic targets, as the main preventive measure for vascular complications, patients with type 1 diabetes need lifelong administration of insulin in a regimen that allows them to have euglycemia both before and after eating. For this, optimal insulin therapy regimens have been created, which necessarily include short-acting insulin (with the main meal) and medium or long-acting insulin as basal. This mode of administration allows you to maximize bring the daily fluctuations of insulin administered to the natural rhythm of insulin secretion in healthy people.

About the Authors

M. V. Shestakova

Endocrinology Research Centre


Russian Federation


L. A. Chugunova

Endocrinology Research Centre


Russian Federation


M. Sh. Shamkhalova

Endocrinology Research Centre


Russian Federation


References

1. Балаболкин М. И., Клебанова Е. М., Креминская В. М. Лечение сахарного диабета и его осложнений: Руководство для врачей. - М., 2005.

2. Дедов И. И., Шестакова М. В. Сахарный диабет: Руководство для врачей. - М., 2003.

3. Dalley G., Rosenstock J., Moses R. G, Ways K. // Diabetes Care. - 2004. - Vol. 27. - P. 2362-2368.

4. Rakatzi L, Seipke G., Eckel J. // Biochem. Biophys. Res. Commun. - 2003. - Abstr. 775.

5. Rakatzi I., Ramrath S., Leddwig B. et al. // Diabetes. - 2003. - Vol. 52. - P. 2227-2238.

6. Sandra L. // Drugs Today. - 2005. - Vol. 41. - P. 438.


Review

For citations:


Shestakova M.V., Chugunova L.A., Shamkhalova M.Sh. Apidra is a new insulin analogue for the treatment of vascular complications in diabetes. Problems of Endocrinology. 2007;53(3):35-38. (In Russ.) https://doi.org/10.14341/probl200753335-38

Views: 23949


ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)