Diuretic-induced edemas: Psychoendocrine aspects

Abstract

Idiopathic edema (IO), that is, fluid retention that is not associated with the menstrual cycle or any disease, occurs in 12–33% of women of reproductive age [1, 2, 4] and often leads to abuse of diuretics [7], which can cause a paradoxical increase in edema (diuretic-induced edema - DIO). The pathogenesis of AI is unclear; perhaps it involves both the central mechanisms of regulation of water-salt metabolism, and the expansion and increase of capillary permeability due to changes in the tone of autonomic nerve endings, orthostatic retention of sodium and water, etc.