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Brain GABA-receptor systems in functional thyroid disorders

https://doi.org/10.14341/probl200955528-30

Abstract

This experimental study was designed to evaluate effects of hypo- and hyperthyroidism on the density of 3H-muscimol and 3H-diazepam-binding sites in synaptic membranes of the rat brain. It was shown that density of both 3H-muscimol and 3H-diazepam-binding sites increases in animals with hypothyroidism and decreases in hyperthyroidism. This difference may account for the predominance of general inhibitory reaction in animals with hypothyroidism and general excitation in hyperthyroid rats.

About the Authors

F K Inoyatova

Tashkent Medical Academy


Uzbekistan


A K Tonkikh

M.Ulugbek National University


Uzbekistan


G T Yakubova

Tashkent Medical Academy


Uzbekistan


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Review

For citations:


Inoyatova F.K., Tonkikh A.K., Yakubova G.T. Brain GABA-receptor systems in functional thyroid disorders. Problems of Endocrinology. 2009;55(5):28-30. (In Russ.) https://doi.org/10.14341/probl200955528-30

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)