Morphometric analysis of the thyroid after its resection

Abstract

Experimental studies of the regenerative processes in the resected thyroid were carried out 30 days after the operation in 30 albino rats with different volumes of tissue left. Qualitative methods were used: organometry and histometry. After moderate (40-65%) resection the regenerate was characterized by the development of quantitative signs of increased functional activity and by sufficiently high compensatory potential. More radical resection was associated with the development of structural signs of functional overstrain of the regenerating portion of the thyroid, manifesting by an increase in the content of thyrocytes, disappearance of colloid, and development of perivascular edema and dystrophy of an appreciable portion of epitheliocytes.