Adrenocortical and testicular hormones during emotional stress in rats genetically predisposed to cataleptic reaction
https://doi.org/10.14341/probl199743138-39
Abstract
GC rats bred from Wistar stock for genetic predisposition to cataleptic reaction are characterized by a slightly lower blood testosterone level than the control Wistar rats. This difference becomes significant after immobilization stress when the level of testosterone increases by 14% in GC and by 61% in Wistar rats (p<0.05). Stress brought about a 68% increase in DOC production by the adrenal tissue in Wistar but caused no changes in GS animals. Stress-induced decrease in aldosterone production was greater in GC and resulted in a significant difference between the two strains (0.77 ± 0.09 and 0.46 ± 0.06 mg/100 mg tissue, p<0.05). The detected endocrine characteristics of GC rats resemble the picture of chronic stress and are similar to those known about male schizophrenics.
About the Authors
K. A. ShulgaInstitute of Cytology and Genetics SB RAS
Russian Federation
T. A. Alekhina
Institute of Cytology and Genetics SB RAS
Russian Federation
V. G. Kolpakov
Institute of Cytology and Genetics SB RAS
Russian Federation
References
1. Колпаков В. Г. Кататония у животных. — Новосибирск, 1990.
2. Минскер Э. 77. // Журн. невропатол. и психиатр. — 1963. - № 9. - С. 1388-1392.
3. Панков Ю. А., Усватова И. Я. // Методы исследования некоторых гормонов и медиаторов. — М., 1965. — С. 137-145.
4. Тавадян Д. С., Гончаров Н. П. // Бюл. экспер. биол. — 1980- № 12. - С. 663-665.
5. Трут Л. Н. Очерки по генетике поведения. — Новосибирск, 1978.
6. Шульга В. А. // Пробл. эндокринол. — 1981. — № 2. — С. 52-57.
7. Bambino Т. Н., Hsueh A. J. W. // Endocrinology. — 1981. — Vol. 108. - Р. 2142-2148.
8. Brambilla F., Penati G. // Influence of Hormones on the Nervous System. — Basel. — 1970. — P. 482—493.
9. Gallup G. G., Maser J. D. // Psychopathology: Experimental Models. — San Francisco. — 1977. — P. 334—357.
10. Glaz E., Vecsei P. Aldosterone. — Budapest, 1971.
11. Gray G. D., Smith E. A., Damassa B. A. et al. // Neuroendocrinology. - 1978. - Vol. 25. - P. 247-256.
12. O'Brien M. J., Levell M. J., Hullen R. P. // J. Endocrinol. — 1979. - Vol. 80. - P. 41-50.
13. Tache Y., DuRuisseau P., Tache Y. et al. // Neuroendocrinology. _ 1976. - Vol. 22. - P. 325-336.
14. Tourney G., Hatfield L. M. // Biol. Psychiatr. — 1973. — Vol. 6. - P. 23-36.
Review
For citations:
Shulga K.A., Alekhina T.A., Kolpakov V.G. Adrenocortical and testicular hormones during emotional stress in rats genetically predisposed to cataleptic reaction. Problems of Endocrinology. 1997;43(1):38-39. (In Russ.) https://doi.org/10.14341/probl199743138-39
Views:
1465
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).
Email this article 
.jpg){kind=logo}
