The change in the content of certain hormones in the blood of rats under the central action of proteolysis inhibitors and protein synthesis
https://doi.org/10.14341/probl199743446-47
Abstract
Changes in the blood serum progesterone, estradiol, thyrotropic and thyroid hormone levels after intracerebroventricular injection of protease inhibitor contrycal in a dose of 100 ng and protein synthesis inhibitor anisomycin in a dose of 50 pg were studied in male rats. Central administration of contrycal significantly decreased the levels of thyrotropic hormone (p<0.05) and estradiol (p<0.001) and increased the level of T4 (p<0.05). Central administration of anisomycin decreased the levels of thyrotropic hormone (p<0.001) and estradiol. The latency of alteration of thyrotropic hormone and T4 levels is within 1 to 3 h, that of estradiol less than 1 h.
About the Authors
D. B. SandakovInstitute of Physiology, Academy of Sciences of the Republic of Belarus
Belarus
I. N. Semenenya
Institute of Physiology, Academy of Sciences of the Republic of Belarus
Belarus
A. V. Gurin
Institute of Physiology, Academy of Sciences of the Republic of Belarus
Belarus
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Review
For citations:
Sandakov D.B., Semenenya I.N., Gurin A.V. The change in the content of certain hormones in the blood of rats under the central action of proteolysis inhibitors and protein synthesis. Problems of Endocrinology. 1997;43(4):46-47. (In Russ.) https://doi.org/10.14341/probl199743446-47
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