Use of dexamethasone for the differential diagnosis of dwarfism
https://doi.org/10.14341/probl11330
Abstract
The capacity of somatotrophs to respond with secretion of growth hormones to dexamethasone administration was studied in children with different forms of dwarfism. In cases of growth delay caused by deficiency of growth hormone the content of STH during dexamethasone test was at the basal level. In the rest cases blood plasma (serum) STH levels increased at the 180th min after dexamethasone administration. A 6 to 50-fold increase of blood STH level was observed in the presence of intact somatotropic function of the hypophysis. Dexamethasone is recommended for the assessment, of the function of somatotrophic state in practical medicine.
About the Authors
S. S. PankovaEndocrinological research center RAMS
Russian Federation
Т I. Buraya
Endocrinological research center RAMS
Russian Federation
N. Р. Goncharov
Endocrinological research center RAMS
Russian Federation
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Review
For citations:
Pankova S.S., Buraya Т.I., Goncharov N.Р. Use of dexamethasone for the differential diagnosis of dwarfism. Problems of Endocrinology. 1995;41(1):12-13. (In Russ.) https://doi.org/10.14341/probl11330
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