Reactions of the paraventricular hypothalamic nucleus and dorsal motor nucleus of vagus of rats to changes of the gravitational environment
https://doi.org/10.14341/probl11492
Abstract
Morphologic study of the paraventricular hypothalamic nucleus (PVN) and of the dorsal nucleus of the vagus (DNV) in the brain of Wistar-SPF rats exposed to weightlessness during a 14-day mission on Cosmos-2044 biosatellite and to Earth gravitation during 811 h after landing showed a reliable reduction of the cross-sectional area of the nucleolus in the neurons of the median parvicellular subnucleus, an increase of this parameter in the neurons of the lateral magnocellular subnucleus, and a trend to its decrease in the neurons of the posterior parvicellular subnucleus. As for the DNV, a reliable decrease in the cross-sectional area of the nucleolus in the neurons and an increased number of neurons with high and moderate acetylcholinesterase (ACE) and butyrylcholinesterase activities of its rostral portion were revealed, as well as a reduction of the number of neurons with high and moderate ACE activity in the median portion of DNV. In the caudal portion of DNV no reliable changes in the studied parameters were detected.
About the Authors
О. I. FidelinaInstitute of experimental endocrinology of Endocrinology research centre of Russian Academy of medical Sciences; Institute of biomedical problems, state scientific center of the Russian Federation
Russian Federation
O. S. Gorbatyuk
Institute of experimental endocrinology of Endocrinology research centre of Russian Academy of medical Sciences; Institute of biomedical problems, state scientific center of the Russian Federation
Russian Federation
I. B. Krasnov
Institute of experimental endocrinology of Endocrinology research centre of Russian Academy of medical Sciences; Institute of biomedical problems, state scientific center of the Russian Federation
Russian Federation
I. G. Akmayev
Institute of experimental endocrinology of Endocrinology research centre of Russian Academy of medical Sciences; Institute of biomedical problems, state scientific center of the Russian Federation
Russian Federation
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Review
For citations:
Fidelina О.I., Gorbatyuk O.S., Krasnov I.B., Akmayev I.G. Reactions of the paraventricular hypothalamic nucleus and dorsal motor nucleus of vagus of rats to changes of the gravitational environment. Problems of Endocrinology. 1995;41(6):35-38. (In Russ.) https://doi.org/10.14341/probl11492
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