The triad of adenohypophyseal and pituitary pedicle hypoplasia and neurohypophyseal ectopy. MR tomographic diagnosis
https://doi.org/10.14341/probl11604
Abstract
The patterns and prevalence of hypothalamo-pituitary abnormalities in children with somatotropic insufficiency were studied using magnetic resonance tomography (MRT). The findings of clinical hormonal analyses and MRT are analyzed in 71 children with various forms of somatotropic insufficiency. High incidence of sellar abnormalities (87.3%) was detected among children with hypopituitarism. Combined triad of abnormalities (neurohypophyseal ectopy, pituitary pedicle aplasia/hypoplasia, and adenohypophysis hypoplasia) ranks first (33.8%) in the structure of detected diseases. This triad was detected in children with isolated somatotropin deficiency and with multiple deficiency of adenohypophyseal hormones. It is associated with de Morsier syndrome (hypopituitarism combined with septooptic dysplasia) and other congenital abnormalities of brain structures).
About the Authors
I. I. DedovEndocrinology Research Center, RAMS
Russian Federation
О. V. Fofanova
Endocrinology Research Center, RAMS
Russian Federation
A. V. Vorontsov
Endocrinology Research Center, RAMS
Russian Federation
V. P. Vladimirova
Endocrinology Research Center, RAMS
Russian Federation
V. A. Peterkova
Endocrinology Research Center, RAMS
Russian Federation
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Review
For citations:
Dedov I.I., Fofanova О.V., Vorontsov A.V., Vladimirova V.P., Peterkova V.A. The triad of adenohypophyseal and pituitary pedicle hypoplasia and neurohypophyseal ectopy. MR tomographic diagnosis. Problems of Endocrinology. 2001;47(5):13-17. (In Russ.) https://doi.org/10.14341/probl11604
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