Plasma protein peroxidation in patients with type 1 diabetes mellitus
https://doi.org/10.14341/probl11609
Abstract
Oxidative plasma protein destruction was studied in children with type 1 diabetes mellitus and healthy children. The duration of the disease was 3-5 years. The degree of spontaneous and metal-catalyzed protein oxidation was determined by the interaction of oxidized amino acid residues with 2.4-dinitrophenylhydrazine. The plasma from children with type 1 diabetes mellitus showed a higher level ofperoxidation products than that from healthy children.
About the Authors
M. A. FlerovPavlov Institute of Physiology RAS; Pavlov St. Petersburg Medical University
Russian Federation
N. N. Smirnova
Pavlov Institute of Physiology RAS; Pavlov St. Petersburg Medical University
Russian Federation
Z. V. Svetlova
Pavlov Institute of Physiology RAS; Pavlov St. Petersburg Medical University
Russian Federation
References
1. Арчаков А. И., Мохосеева И. М. // Биохимия. - 1989. - Т. 54, № 2. - С. 179-186.
2. Дубинина Е. Е., Шугалей И. В. // Успехи соврем, биол. - 1993. - Т. 113, вып. I. - С. 71-81.
3. Дубинина Е. Е., Бурмистров С. О., Ходов Д. А. и др. // Вопр. мед. химии. - 1995. - Т. 41, № 1. - С. 24-26.
4. Дубинина Е. Е., Морозова М. Г., Леонова Н. В. и др. // Там же. - 2000. - Т. 46, № 4. - С. 398-409.
5. Ефимов А. С., Науменко В. Г. // Пробл. эндокринол. - 1985. - Т. 31, № 1. - С. 3-9.
6. Кондратьев Я. Ю., Носиков В. В., Дедов И. И. // Там же. - 1998. - Т. 44, № 1. - С. 43-51.
7. Лисицина Т. А., Васильева И. М., Дурнев А. Д. // Докл. АН. - 1999. - Т. 365, № 2. - С. 263-266.
8. Любицкий О. Б., Давыдов Б. В., Елыианский И. В. и др. // Вопр. мед. химии. - 1998. - Т. 44, № 6. - С. 565-570.
9. Татьяненко Л. В, Богданов Г. Н, Варфоломеев В. Н. и др. // Там же. - С. 551-558.
10. Giugiano D., Acompora R., O’Onofrio F. // Diabet. Metab. – 1993. - Vol. 20. - P. 445-453.
11. Levine R. T., Garland D., Oliver C. N. et al. // Meth. Enzymol. - 1990. - Vol. 186. - P. 464-478.
12. Oberley L. W. // Free Rad. Biol. Med. - 1988. - Vol. 5. - P. 113-124.
13. Stadtman E. R. // Ibid. - 1990. - Vol. 9. - P. 315-325.
Review
For citations:
Flerov M.A., Smirnova N.N., Svetlova Z.V. Plasma protein peroxidation in patients with type 1 diabetes mellitus. Problems of Endocrinology. 2003;49(4):3-4. (In Russ.) https://doi.org/10.14341/probl11609

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