Platelet activity in patients with hyper- and hypoparathyroidism
https://doi.org/10.14341/probl11753
Abstract
Platelet aggregatory activity was studied in a patient with hyperparathyroidism before and after parathyroid adenomectomy and in 3 patients with hypoparathyroidism. In these patients, changes in the aggregation activity of platelet were evaluated after their incubation with parathyroid hormone. The patient with hyperparathyroidism was found to have activated platelets, their high readiness for an aggregation response, increased and a highly effective aggregatory activity and insignificantly decreased stability of formed platelet aggregates. After parathyroid adenomectomy there was a partial recovery ofplatelet functional activity. The patients with hypoparathyroidism had a lower platelet functional activity as compared with the controls. Preincubation of platelet-rich plasma from the patients with hypoparathyroidism with parathyroid hormone caused a varying recovery of platelet functional activity.
About the Authors
V. F. KirichukSaratov State Medical University
Russian Federation
F. G. Arefyev
Saratov State Medical University
Russian Federation
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Review
For citations:
Kirichuk V.F., Arefyev F.G. Platelet activity in patients with hyper- and hypoparathyroidism. Problems of Endocrinology. 2003;49(5):32-38. (In Russ.) https://doi.org/10.14341/probl11753
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