Growth in the pubertal period in patients with genetic disorders of sex hormone effects and secretion
https://doi.org/10.14341/probl11811
Abstract
Classical methods in experimental endocrinology include the removal of endocrine organs in animals, after which they are replaced with presumably active elements in order to demonstrate specific effects. Such experimentation is not considered ethical when examining a person; instead, in order to broaden our understanding of growth and developmental abnormalities, detailed studies of rare genetic disorders that cause an increase in specific defects in hormonal action or secretion can be used. This knowledge can be used in finding the right treatment for disorders that can be much more frequent than the rare conditions discussed below. Some “nature experiments” that can provide similar information about the effect of sex hormones on growth in the puberty period will be described.
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Review
For citations:
Ritzen E. Growth in the pubertal period in patients with genetic disorders of sex hormone effects and secretion. Problems of Endocrinology. 1994;40(2):65-68. (In Russ.) https://doi.org/10.14341/probl11811
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