Incidence of craniopharyngioma relapses in children treated with growth hormone
https://doi.org/10.14341/probl11816
Abstract
By January 15, 1992, the KIGS database included 258 children (the ratio of boys to girls 1.5: 1) with growth hormone deficiency, which developed against the background of craniopharyngioma. The duration of growth hormone (GH) treatment ranged from 0.2 to 15.4 years (average 3.9 years). Over 1338 years of GH treatment (total for all patients), 17 children had a relapse of CF after 0.25-4.8 years (on average 2.3 years) from the start of GH treatment. The age at the time the tumor was detected, the age and SDS for growth at the beginning of GH treatment, the dose of GH, as well as the growth rate before and during the first year of GH treatment did not differ in patients with and without relapse. The recurrence rate was also the same in patients who underwent one surgical treatment, and in those in whom the operation was combined with radiotherapy.
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Review
For citations:
Wilton P., Price D.A. Incidence of craniopharyngioma relapses in children treated with growth hormone. Problems of Endocrinology. 1994;40(2):82-85. (In Russ.) https://doi.org/10.14341/probl11816
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